3.5 cm artificial urinary sphincter cuff erosion occurs predominantly in irradiated patients

Jay Simhan, Allen Morey, Nirmish Singla, Timothy J. Tausch, J. Francis Scott, Gary E Lemack, Claus Roehrborn

Research output: Contribution to journalArticle

44 Scopus citations


Purpose We analyzed our initial 100-case experience with the 3.5 cm artificial urinary sphincter cuff to identify risk factors for cuff erosion. Materials and Methods We reviewed the records of a single surgeon, consecutive series of patients treated with 3.5 cm artificial urinary sphincter cuff placement from September 2009 to August 2013. Each patient underwent single perineal cuff placement via standardized technique. Preoperative characteristics, technical considerations and postoperative outcomes were analyzed and compared to those in a cohort of patients in whom a larger (4.0 cm or greater) artificial urinary sphincter cuff was placed during the same period. We identified clinical factors associated with an increased risk of 3.5 cm artificial urinary sphincter cuff erosion. Results Of the 176 men who met study inclusion criteria during the 4-year period 100 (57%) received the 3.5 cm artificial urinary sphincter cuff and 76 (43%) received a larger cuff (4.0 cm or greater). The continence rate (83% vs 80%, p = 0.65) and mean followup (32 vs 25 months, p = 0.14) were similar in the 2 groups. Erosion developed in 16 of the 176 patients (9%) during the study period, of whom 13 had the 3.5 cm cuff. Of the 100 patients with the 3.5 cm cuff 52 (52%) had a history of radiation, including 11 (21%) with erosion. Cuff erosion developed only rarely in nonirradiated men (2 of 48 or 4%, p = 0.01). A history of radiation was the only significant risk factor associated with 3.5 cm cuff erosion (OR 6.2, 95% CI 1.3-29.5). Conclusions Men with a history of radiation who underwent placement of a 3.5 cm artificial urinary sphincter cuff experienced an increased (21%) risk of cuff erosion.

Original languageEnglish (US)
Pages (from-to)593-597
Number of pages5
JournalJournal of Urology
Issue number2
Publication statusPublished - Feb 1 2015



  • complications
  • urethra
  • urinary bladder
  • urinary incontinence, stress
  • urinary sphincter, artificial

ASJC Scopus subject areas

  • Urology

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