TY - GEN
T1 - 3D H-scan ultrasound imaging system and method for acoustic scatterer size estimation
T2 - 2019 IEEE International Ultrasonics Symposium, IUS 2019
AU - Tai, Haowei
AU - Khairalseed, Mawia
AU - Hoyt, Kenneth
N1 - Funding Information:
This study was supported by National Institutes of Health (NIH) grants K25EB017222, R01EB025841, and Cancer Prevention Research Institute of Texas (CPRIT) grant RP180670.
Publisher Copyright:
© 2019 IEEE.
PY - 2019/10
Y1 - 2019/10
N2 - H-scan ultrasound (US) is an innovative real-time imaging technology that depicts the relative size of acoustic scattering objects and structures. The purpose of this research was to develop a novel 3-dimensional (3D) H-scan US imaging approach for tissue classification in volume space. Using a programmable research scanner (Vantage 256, Verasonics Inc, Kirkland, WA) equipped with a custom-built volumetric imaging transducer (4DL7, Vermon, Tours, France), radio frequency (RF) data was collected for offline processing. H-scan US images were constructed after applying a set of convolutional filters based on Gaussian-weighted Hermite polynomials. These functions are related to different sized scattering objects. Preliminary studies were conducted using homogeneous gelatin-based tissue-mimicking phantom materials embedded with acoustic scatterers of varying size (15, 30 or 250 μm) and concentrations (0.1, 0.3, 0.5 or 1.0 %). In vitro results indicate that 3D H-scan US imaging can detect acoustic scatterers of varying size (p < 0.01) and independent of scatterer concentration (p > 0.05). Overall, our preliminary in vitro findings reveal that 3D H-scan US imaging allows the visualization of different tissue scatterer patterns.
AB - H-scan ultrasound (US) is an innovative real-time imaging technology that depicts the relative size of acoustic scattering objects and structures. The purpose of this research was to develop a novel 3-dimensional (3D) H-scan US imaging approach for tissue classification in volume space. Using a programmable research scanner (Vantage 256, Verasonics Inc, Kirkland, WA) equipped with a custom-built volumetric imaging transducer (4DL7, Vermon, Tours, France), radio frequency (RF) data was collected for offline processing. H-scan US images were constructed after applying a set of convolutional filters based on Gaussian-weighted Hermite polynomials. These functions are related to different sized scattering objects. Preliminary studies were conducted using homogeneous gelatin-based tissue-mimicking phantom materials embedded with acoustic scatterers of varying size (15, 30 or 250 μm) and concentrations (0.1, 0.3, 0.5 or 1.0 %). In vitro results indicate that 3D H-scan US imaging can detect acoustic scatterers of varying size (p < 0.01) and independent of scatterer concentration (p > 0.05). Overall, our preliminary in vitro findings reveal that 3D H-scan US imaging allows the visualization of different tissue scatterer patterns.
KW - H-scan ultrasound
KW - acoustic scatterers
KW - tissue classification
KW - ultrasound
KW - volumetric imaging
UR - http://www.scopus.com/inward/record.url?scp=85077556770&partnerID=8YFLogxK
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U2 - 10.1109/ULTSYM.2019.8926174
DO - 10.1109/ULTSYM.2019.8926174
M3 - Conference contribution
AN - SCOPUS:85077556770
T3 - IEEE International Ultrasonics Symposium, IUS
SP - 1515
EP - 1518
BT - 2019 IEEE International Ultrasonics Symposium, IUS 2019
PB - IEEE Computer Society
Y2 - 6 October 2019 through 9 October 2019
ER -