3D in vivo imaging of rat hearts by high frequency ultrasound and its application in myofiber orientation wrapping

Xulei Qin, Silun Wang, Ming Shen, Xiaodong Zhang, Stamatios Lerakis, Mary B. Wagner, Baowei Fei

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Abstract

Cardiac ultrasound plays an important role in the imaging of hearts in basic cardiovascular research and clinical examinations. 3D ultrasound imaging can provide the geometry or motion information of the heart. Especially, the wrapping of cardiac fiber orientations to the ultrasound volume could supply useful information on the stress distributions and electric action spreading. However, how to acquire 3D ultrasound volumes of the heart of small animals in vivo for cardiac fiber wrapping is still a challenging problem. In this study, we provide an approach to acquire 3D ultrasound volumes of the rat hearts in vivo. The comparison between both in vivo and ex vivo geometries indicated 90.1% Dice similarity. In this preliminary study, the evaluations of the cardiac fiber orientation wrapping errors were 24.7° for the acute angle error and were 22.4° for the inclination angle error. This 3D ultrasound imaging and fiber orientation estimation technique have potential applications in cardiac imaging.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2015
Subtitle of host publicationUltrasonic Imaging and Tomography
EditorsNeb Duric, Johan G. Bosch
PublisherSPIE
ISBN (Electronic)9781628415094
DOIs
Publication statusPublished - Jan 1 2015
Externally publishedYes
EventMedical Imaging 2015: Ultrasonic Imaging and Tomography - Orlando, United States
Duration: Feb 22 2015Feb 23 2015

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9419
ISSN (Print)1605-7422

Other

OtherMedical Imaging 2015: Ultrasonic Imaging and Tomography
CountryUnited States
CityOrlando
Period2/22/152/23/15

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Keywords

  • cardiac fiber orientations
  • cardiac imaging
  • echocardiography
  • In vivo 3D ultrasound imaging
  • magnetic resonance diffusion tensor imaging (MR-DTI)
  • small animal imaging

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

Cite this

Qin, X., Wang, S., Shen, M., Zhang, X., Lerakis, S., Wagner, M. B., & Fei, B. (2015). 3D in vivo imaging of rat hearts by high frequency ultrasound and its application in myofiber orientation wrapping. In N. Duric, & J. G. Bosch (Eds.), Medical Imaging 2015: Ultrasonic Imaging and Tomography [941906] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9419). SPIE. https://doi.org/10.1117/12.2082326