4D computed tomography reconstruction from few-projection data via temporal non-local regularization

Xun Jia, Yifei Lou, Bin Dong, Zhen Tian, Steve Jiang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

43 Scopus citations

Abstract

4D computed tomography (4D-CT) is an important modality in medical imaging due to its ability to resolve patient anatomy motion in each respiratory phase. Conventionally 4D-CT is accomplished by performing the reconstruction for each phase independently as in a CT reconstruction problem. We propose a new 4D-CT reconstruction algorithm that explicitly takes into account the temporal regularization in a non-local fashion. By imposing a regularization of a temporal non-local means (TNLM) form, 4D-CT images at all phases can be reconstructed simultaneously based on extremely under-sampled x-ray projections. Our algorithm is validated in one digital NCAT thorax phantom and two real patient cases. It is found that our TNLM algorithm is capable of reconstructing the 4D-CT images with great accuracy. The experiments also show that our approach outperforms standard 4D-CT reconstruction methods with spatial regularization of total variation or tight frames.

Original languageEnglish (US)
Title of host publicationMedical Image Computing and Computer-Assisted Intervention, MICCAI2010 - 13th International Conference, Proceedings
Pages143-150
Number of pages8
EditionPART 1
DOIs
StatePublished - 2010
Event13th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2010 - Beijing, China
Duration: Sep 20 2010Sep 24 2010

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
NumberPART 1
Volume6361 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Other

Other13th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2010
Country/TerritoryChina
CityBeijing
Period9/20/109/24/10

ASJC Scopus subject areas

  • Theoretical Computer Science
  • General Computer Science

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