5α-reduced androgens in the human fetal testis

F. W. George, B. R. Carr, J. F. Noble, J. D. Wilson

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

The androgen content was measured in testes from 34 male and in ovaries from 30 female embryos that varied in age from less than 12 to approximately 20 weeks. The 5α-reduced androgens dihydrotestosterone and 3α-androstanediol were found in testes at a level of about a 30th of that of testosterone at all ages examined, whereas very little or no testosterone, androstenedione, or either of the 5α-reduced andfogens were detected in the ovaries. Whether dihydrotestosterone plays a role in the development of the testes is unknown.

Original languageEnglish (US)
Pages (from-to)628-630
Number of pages3
JournalJournal of Clinical Endocrinology and Metabolism
Volume64
Issue number3
DOIs
StatePublished - Mar 1987

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

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