5-thiomannosides block the biosynthesis of dolichol-linked oligosaccharides and mimic class I congenital disorders of glycosylation

Chemical Compounds

• Dolichol-Linked Oligosaccharide 100%
• Glycosylation 50%
• Disorder 43%
• Biosynthesis 42%
• Block Like Crystal 34%
• Glycoside 32%
• Prohormone 25%
• Nucleotide-Sugar 24%
• N-Glycan 21%
• Mannose 18%
• Glycoprotein 15%
• Electrophoresis 15%
• Nitrogen Atom 14%
• Carbohydrate 13%
• Donor 11%
• Protein 6%

Medicine & Life Sciences

• Dolichols 80%
• Congenital Disorders of Glycosylation 78%
• Oligosaccharides 56%
• Sterol Regulatory Element Binding Protein 2 40%
• Glycosylation 25%
• Glycosides 20%
• Cricetulus 17%
• Ovary 14%
• Subtilisin 12%
• Enzyme Precursors 10%
• Sterols 9%
• Mannose 9%
• Isoenzymes 8%
• Nitrogen 8%
• Sugars 8%
• Endoplasmic Reticulum 8%
• Electrophoresis 8%
• Polysaccharides 7%
• Carbohydrates 7%
• Glycoproteins 7%
• Peptide Hydrolases 7%
• Nucleotides 6%
• Transcription Factors 6%
• Proteins 3%