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• 20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism

  Akbulut, T., Regner, K. R., Roman, R. J., Avner, E. D., Falck, J. R. & Park, F., Sep 2009, In: American Journal of Physiology - Renal Physiology. 297, 3, p. F662-F670

  Research output: Contribution to journal › Article › peer-review
  44 Scopus citations

• 20-HETE Activates the Transcription of Angiotensin-Converting Enzyme via Nuclear Factor-κB Translocation and Promoter Binding

  Garcia, V., Shkolnik, B., Milhau, L., Falck, J. R. & Schwartzman, M. L., Mar 1 2016, In: Journal of Pharmacology and Experimental Therapeutics. 356, 3, p. 525-533 9 p.

  Research output: Contribution to journal › Article › peer-review
  28 Scopus citations

• 20-HETE agonists and antagonists in the renal circulation

  Alonso-Galicia, M., Falck, J. R., Reddy, K. M. & Roman, R. J., Nov 1999, In: American Journal of Physiology - Renal Physiology. 277, 5 46-5, p. F790-F796

  Research output: Contribution to journal › Article › peer-review
  114 Scopus citations

• 20-HETE and F₂-isoprostanes in the metabolic syndrome: the effect of weight reduction

  Tsai, I. J., Croft, K. D., Mori, T. A., Falck, J. R., Beilin, L. J., Puddey, I. B. & Barden, A. E., Jan 15 2009, In: Free Radical Biology and Medicine. 46, 2, p. 263-270 8 p.

  Research output: Contribution to journal › Article › peer-review
  63 Scopus citations

• 20-HETE can act as a nonhypoxic regulator of HIF-1α in human microvascular endothelial cells

  Guo, A. M., Scicli, G., Sheng, J., Falck, J. C., Edwards, P. A. & Scicli, A. G., Aug 1 2009, In: American Journal of Physiology - Heart and Circulatory Physiology. 297, 2, p. H602-H613

  Research output: Contribution to journal › Article › peer-review
  32 Scopus citations

• 20-HETE contributes to ischemia-induced angiogenesis

  Chen, L., Joseph, G., Zhang, F. F., Nguyen, H., Jiang, H., Gotlinger, K. H., Falck, J. R., Yang, J., Schwartzman, M. L. & Guo, A. M., Aug 1 2016, In: Vascular Pharmacology. 83, p. 57-65 9 p.

  Research output: Contribution to journal › Article › peer-review
  16 Scopus citations

• 20-HETE contributes to myogenic activation of skeletal muscle resistance arteries in Brown Norway and Sprague-Dawley rats

  Frisbee, J. C., Roman, R. J., Falck, J. R., Krishna, M. & Lombard, J. H., 2001, In: Microcirculation. 8, 1, p. 45-55 11 p.

  Research output: Contribution to journal › Article › peer-review
  31 Scopus citations

• 20-HETE increases superoxide production and activates NAPDH oxidase in pulmonary artery endothelial cells

  Medhora, M., Chen, Y., Gruenloh, S., Harland, D., Bodiga, S., Zielonka, J., Gebremedhin, D., Gao, Y., Falck, J. R., Anjaiah, S. & Jacobs, E. R., May 2008, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 294, 5, p. L902-L911

  Research output: Contribution to journal › Article › peer-review
  60 Scopus citations

• 20-HETE increases survival and decreases apoptosis in pulmonary arteries and pulmonary artery endothelial cells

  Dhanasekaran, A., Bodiga, S., Gruenloh, S., Gao, Y., Dunn, L., Falck, J. R., Buonaccorsi, J. N., Medhora, M. & Jacobs, E. R., Mar 2009, In: American Journal of Physiology - Heart and Circulatory Physiology. 296, 3, p. H777-H786

  Research output: Contribution to journal › Article › peer-review
  38 Scopus citations

• 20-HETE-induced nitric oxide production in pulmonary artery endothelial cells is mediated by NADPH oxidase, H₂O₂, and PI3-kinase/Akt

  Bodiga, S., Gruenloh, S. K., Gao, Y., Manthati, V. L., Dubasi, N., Falck, J. R., Medhora, M. & Jacobs, E. R., Apr 2010, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 298, 4, p. L564-L574

  Research output: Contribution to journal › Article › peer-review
  27 Scopus citations

• 20-HETE induces remodeling of renal resistance arteries independent of blood pressure elevation in hypertension

  Ding, Y., Wu, C. C., Garcia, V., Dimitrova, I., Weidenhammer, A., Joseph, G., Zhang, F., Manthati, V. L., Falck, J. R., Capdevila, J. H. & Schwartzman, M. L., Sep 1 2013, In: American Journal of Physiology - Renal Physiology. 305, 5, p. F753-F763

  Research output: Contribution to journal › Article › peer-review
  24 Scopus citations

• 20-HETE interferes with insulin signaling and contributes to obesity-driven insulin resistance

  Gilani, A., Agostinucci, K., Hossain, S., Pascale, J. V., Garcia, V., Adebesin, A. M., Falck, J. R. & Schwartzman, M. L., Feb 2021, In: Prostaglandins and Other Lipid Mediators. 152, 106485.

  Research output: Contribution to journal › Article › peer-review
  8 Scopus citations

• 20-HETE is an endogenous inhibitor of the large-conductance Ca²⁺-activated K⁺ channel in renal arterioles

  Zou, A. P., Fleming, J. T., Falck, J. R., Jacobs, E. R., Gebremedhin, D., Harder, D. R. & Roman, R. J., 1996, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 270, 1 39-1, p. R228-R237

  Research output: Contribution to journal › Article › peer-review
  277 Scopus citations

• 20-HETE mediates the effect of parathyroid hormone and protein kinase C on renal phosphate transport

  Silverstein, D. M., Barac-Nieto, M., Falck, J. R. & Spitzer, A., Mar 1998, In: Prostaglandins Leukotrienes and Essential Fatty Acids. 58, 3, p. 209-213 5 p.

  Research output: Contribution to journal › Article › peer-review
  17 Scopus citations

• 20-HETE modulates myogenic response of skeletal muscle resistance arteries from hypertensive Dahl-SS rats

  Frisbee, J. C., Roman, R. J., Krishna, U. M., Falck, J. R. & Lombard, J. H., 2001, In: American Journal of Physiology - Heart and Circulatory Physiology. 280, 3 49-3, p. H1066-H1074

  Research output: Contribution to journal › Article › peer-review
  39 Scopus citations

• 20-HETE Participates in Intracerebral Hemorrhage-Induced Acute Injury by Promoting Cell Ferroptosis

  Han, R., Wan, J., Han, X., Ren, H., Falck, J. R., Munnuri, S., Yang, Z. J. & Koehler, R. C., Nov 12 2021, In: Frontiers in Neurology. 12, 763419.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• 20-HETE pathway antagonists inhibit rat small mesenteric artery tone

  Looft-Wilson, R. C., Falck, J. R., Krishna, U. M. & Gisolfi, C. V., 2002, In: Microvascular Research. 64, 2, p. 349-352 4 p.

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations

• 20-HETE regulates the angiogenic functions of human endothelial progenitor cells and contributes to angiogenesis in vivo

  Chen, L., Ackerman, R., Saleh, M., Gotlinger, K. H., Kessler, M., Mendelowitz, L. G., Falck, J. R., Arbab, A. S., Scicli, A. G., Schwartzman, M. L., Yang, J. & Guo, A. M., Mar 2014, In: Journal of Pharmacology and Experimental Therapeutics. 348, 3, p. 442-451 10 p.

  Research output: Contribution to journal › Article › peer-review
  49 Scopus citations

• 20-HETE Relaxes Bovine Coronary Arteries Through the Release of Prostacyclin

  Pratt, P. F., Falck, J. R., Reddy, K. M., Kurian, J. B. & Campbell, W. B., Jan 1998, In: Hypertension. 31, 1, p. 237-241 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  38 Scopus citations

• 20-HETE Signals Through G-Protein-Coupled Receptor GPR75 (G_q) to Affect Vascular Function and Trigger Hypertension

  Garcia, V., Gilani, A., Shkolnik, B., Pandey, V., Zhang, F. F., Dakarapu, R., Gandham, S. K., Reddy, R. R., Graves, J. P., Gruzdev, A., Zeldin, D. C., Capdevila, J. H., Falck, J. R. & Schwartzman, M. L., May 26 2017, In: Circulation research. 120, 11, p. 1776-1788 13 p.

  Research output: Contribution to journal › Article › peer-review
  67 Scopus citations

• 20-HETE synthesis inhibition promotes cerebral protection after intracerebral hemorrhage without inhibiting angiogenesis

  Han, X., Zhao, X., Lan, X., Li, Q., Gao, Y., Liu, X., Wan, J., Yang, Z., Chen, X., Zang, W., Guo, A. M., Falck, J. R., Koehler, R. C. & Wang, J., Aug 1 2019, In: Journal of Cerebral Blood Flow and Metabolism. 39, 8, p. 1531-1543 13 p.

  Research output: Contribution to journal › Article › peer-review
  31 Scopus citations

• 20-Hydroxy-5,8,11,14-eicosatetraenoic acid mediates endothelial dysfunction via IκB kinase-dependent endothelial nitric-oxide synthase uncoupling

  Cheng, J., Wu, C. C., Gotlinger, K. H., Zhang, F., Falck, J. R., Narsimhaswamy, D. & Laniado-Schwartzman, M., Jan 2010, In: Journal of Pharmacology and Experimental Therapeutics. 332, 1, p. 57-65 9 p.

  Research output: Contribution to journal › Article › peer-review
  73 Scopus citations

• 20-Hydroxyeicosatetraenoic acid (20-HETE): Structural determinants for renal vasoconstriction

  Yu, M., Alonso-Galicia, M., Sun, C. W., Roman, R. J., Ono, N., Hirano, H., Ishimoto, T., Reddy, Y. K., Katipally, K. R., Reddy, K. M., Gopal, V. R., Yu, J., Takhi, M. & Falck, J. R., Jul 3 2003, In: Bioorganic and Medicinal Chemistry. 11, 13, p. 2803-2821 19 p.

  Research output: Contribution to journal › Article › peer-review
  28 Scopus citations

• 20-Hydroxyeicosatetraenoic Acid (20-HETE) Metabolism in Coronary Endothelial Cells

  Kaduce, T. L., Fang, X., Harmon, S. D., Oltman, C. L., Dellsperger, K. C., Teesch, L. M., Gopal, V. R., Falck, J. R., Campbell, W. B., Weintraub, N. L. & Spector, A. A., Jan 23 2004, In: Journal of Biological Chemistry. 279, 4, p. 2648-2656 9 p.

  Research output: Contribution to journal › Article › peer-review
  47 Scopus citations

• 20-Hydroxyeicosatetraenoic acid (HETE)-dependent hypertension in human cytochrome P450 (CYP) 4A11 transgenic mice: Normalization of blood pressure by sodium restriction, hydrochlorothiazide, or blockade of the type 1 angiotensin II receptor

  Savas, Ü., Wei, S., Hsu, M. H., Falck, J. R., Guengerich, F. P., Capdevila, J. H. & Johnson, E. F., Aug 5 2016, In: Journal of Biological Chemistry. 291, 32, p. 16904-16919 16 p.

  Research output: Contribution to journal › Article › peer-review
  25 Scopus citations

• 20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: A study in Cyp1a1-Ren-2 transgenic rats

  Sedláková, L., Kikerlová, S., Husková, Z., Červenková, L., Chábová, V. Č., Zicha, J., Falck, J. R., Imig, J. D., Kompanowska-Jezierska, E., Sadowski, J., Krátký, V., Červenka, L. & Kopkan, L., Sep 12 2018, In: Bioscience reports. 38, 5, BSR20171496.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  7 Scopus citations

• 20-Hydroxyeicosatetraenoic acid causes endothelial dysfunction via eNOS uncoupling

  Cheng, J., Ou, J. S., Singh, H., Falck, J. R., Narsimhaswamy, D., Pritchard, K. A. & Schwartzman, M. L., Feb 2008, In: American Journal of Physiology - Heart and Circulatory Physiology. 294, 2, p. H1018-H1026

  Research output: Contribution to journal › Article › peer-review
  122 Scopus citations

• 20-Hydroxyeicosatetraenoic acid contributes to the inhibition of K+ channel activity and vasoconstrictor response to angiotensin II in rat renal microvessels

  Fan, F., Sun, C. W., Maier, K. G., Williams, J. M., Pabbidi, M. R., Didion, S. P., Falck, J. R., Zhuo, J. & Roman, R. J., Dec 4 2013, In: PloS one. 8, 12, e82482.

  Research output: Contribution to journal › Article › peer-review
  42 Scopus citations

• 20-Hydroxyeicosatetraenoic acid is an endogenous vasoconstrictor of canine renal arcuate arteries

  Ma, Y. H., Gebremedhin, D., Schwartzman, M. L., Falck, J. R., Clark, J. E., Masters, B. S., Harder, D. R. & Roman, R. J., 1993, In: Circulation research. 72, 1, p. 126-136 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  245 Scopus citations

• 20-Hydroxyeicosatetraenoic acid is an endothelium-dependent vasoconstrictor in rabbit arteries

  Escalante, B., Omata, K., Sessa, W., Lee, S. G., Falck, J. R. & Schwartzman, M. L., Apr 22 1993, In: European Journal of Pharmacology. 235, 1, p. 1-7 7 p.

  Research output: Contribution to journal › Article › peer-review
  65 Scopus citations

• 20-Hydroxyeicosatetraenoic acid is a potent dilator of mouse basilar artery: Role of cyclooxygenase

  Fang, X., Faraci, F. M., Kaduce, T. L., Harmon, S., Modrick, M. L., Hu, S., Moore, S. A., Falck, J. R., Weintraub, N. L. & Spector, A. A., 2006, In: American Journal of Physiology - Heart and Circulatory Physiology. 291, 5, p. H2301-H2307

  Research output: Contribution to journal › Article › peer-review
  37 Scopus citations

• 20-Hydroxyeicosatetraenoic acid is excreted as a glucuronide conjugate in human urine

  Prakash, C., Zhang, J. Y., Falck, J. R., Chauhan, K. & Blair, I. A., Jun 15 1992, In: Biochemical and Biophysical Research Communications. 185, 2, p. 728-733 6 p.

  Research output: Contribution to journal › Article › peer-review
  58 Scopus citations

• 20-hydroxyeicosatetraenoic acid is formed in response to EGF and is a mitogen in rat proximal tubule

  Lin, F., Rios, A., Falck, J. R., Belosludtsev, Y. & Schwartzman, M. L., 1995, In: American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 269, 6 38-6, p. F806-F816

  Research output: Contribution to journal › Article › peer-review
  68 Scopus citations

• 20-Hydroxyeicosatetraenoic acid is formed in response to EGF and is a mitogen in rat proximal tubule

  Lin, F., Rios, A., Falck, J. R., Belosludtsev, Y. & Schwartzman, M. L., Dec 1 1995, In: American Journal of Physiology - Renal Physiology. 269, 6, p. F805-F816

  Research output: Contribution to journal › Article › peer-review
  7 Scopus citations

• 20-Hydroxyeicosatetraenoic acid stimulates nuclear factor-κB activation and the production of inflammatory cytokines in human endothelial cells

  Ishizuka, T., Cheng, J., Singh, H., Vitto, M. D., Manthati, V. L., Falck, J. R. & Laniado-Schwartzman, M., Jan 2008, In: Journal of Pharmacology and Experimental Therapeutics. 324, 1, p. 103-110 8 p.

  Research output: Contribution to journal › Article › peer-review
  130 Scopus citations

• 20-Iodo-14,15-epoxyeicosa-8(Z)-enoyl-3-azidophenylsulfonamide: Photoaffinity labeling of a 14,15-epoxyeicosatrienoic acid receptor

  Chen, Y., Falck, J. R., Manthati, V. L., Jat, J. L. & Campbell, W. B., May 10 2011, In: Biochemistry. 50, 18, p. 3840-3848 9 p.

  Research output: Contribution to journal › Article › peer-review
  42 Scopus citations

• 20 of the most influential people in EMS. Part 2. Interview by Mike Taigman.

  Eisenberg, M., Jones, D., Cason, D., Stults, K., Birnbaum, M., White, R. D., Safar, P., Boyd, D., Overton, J. & Mantooth, R., Aug 2000, In: JEMS : a journal of emergency medical services. 25, 8, p. 53-62 10 p.

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations

• 20-year experience with intraoperative high-dose-rate brachytherapy for pediatric sarcoma: Outcomes, toxicity, and practice recommendations

  Folkert, M. R., Tong, W. Y., Laquaglia, M. P., Wexler, L. H., Chou, A. J., Magnan, H., Zelefsky, M. J. & Wolden, S. L., Oct 1 2014, In: International Journal of Radiation Oncology Biology Physics. 90, 2, p. 362-368 7 p.

  Research output: Contribution to journal › Article › peer-review
  28 Scopus citations

• 20 years of Developmental Cell: Looking back

  Chory, J., Olson, E. N., Solnica-Krezel, L., Munro, S., Fuchs, E., St. Johnston, D., Lefebvre, V., Coupland, G., Millar, S. E. & Lin, H., Dec 6 2021, In: Developmental cell. 56, 23, p. 3181-3184 4 p.

  Research output: Contribution to journal › Article › peer-review

• 211th ENMC International Workshop:: Development of diagnostic criteria and management strategies for McArdle Disease and related rare glycogenolytic disorders to improve standards of care. 17–19 April 2015, Naarden, The Netherlands

  Workshop Participants, Dec 2017, In: Neuromuscular Disorders. 27, 12, p. 1143-1151 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Scopus citations

• 218th ENMC International Workshop:: Revisiting the consensus on standards of care in SMA Naarden, The Netherlands, 19–21 February 2016

  ENMC SMA Workshop Study Group, Jun 2017, In: Neuromuscular Disorders. 27, 6, p. 596-605 10 p.

  Research output: Contribution to journal › Article › peer-review
  34 Scopus citations

• 21st Century Advances in Multimodality Imaging of Obesity for Care of the Cardiovascular Patient

  Neeland, I. J., Yokoo, T., Leinhard, O. D. & Lavie, C. J., Feb 2021, In: JACC: Cardiovascular Imaging. 14, 2, p. 482-494 13 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  11 Scopus citations

• 21st Century Cures Act: Implementation Without Understanding Implication?

  Gerber, D. E., Feb 1 2022, In: JCO Oncology Practice. 18, 2, p. 85-87 3 p.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

• 225Ac-Prostate-Specific Membrane Antigen Therapy for Castration-Resistant Prostate Cancer: A Single-Center Experience

  Sanli, Y., Kuyumcu, S., Simsek, D. H., Büyükkaya, F., Civan, C., Isik, E. G., Ozkan, Z. G., Basaran, M. & Sanli, O., Dec 1 2021, In: Clinical nuclear medicine. 46, 12, p. 943-951 9 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• 22-Alkyl-20-epi-1α,25-dihydroxyvitamin D₃ compounds of superagonistic activity: Syntheses, biological activities and interaction with the receptor

  Yamamoto, K., Inaba, Y., Yoshimoto, N., Choi, M., DeLuca, H. F. & Yamada, S., Mar 8 2007, In: Journal of Medicinal Chemistry. 50, 5, p. 932-939 8 p.

  Research output: Contribution to journal › Article › peer-review
  18 Scopus citations

• 22nd Annual Carrell-Krusen Symposium. Dallas, Texas, USA. February 24-25, 2000. Abstracts

  Iannaccone, S. T., Mar 2000, In: Journal of child neurology. 15, 3, p. 192-201 10 p.

  Research output: Contribution to journal › Article › peer-review

• 22^nd Marabou Symposium: The changing faces of vitamin D

  James, P., Rosenberg, I., Mangelsdorf, D., DeLuca, H., Mathieu, C., Prentice, A., Meyer, H., Heaney, R., Holick, M., Garza, C., Moan, J., Angelin, B., Pedersen, J., Moskilde, L., Cross, H., Tuohimaa, P., Abrams, S., Campbell, M., Takasu, H., Haussler, M. & 4 others, Sitrin, M., Cantorna, M., Hernell, O. & Lamberg-Allardt, C., Oct 2008, In: Nutrition Reviews. 66, SUPPL.2, p. S195-S212

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• 22q13.3 Deletion syndrome: Clinical and molecular analysis using array CGH

  Dhar, S. U., Del Gaudio, D., German, J. R., Peters, S. U., Ou, Z., Bader, P. I., Berg, J. S., Blazo, M., Brown, C. W., Graham, B. H., Grebe, T. A., Lalani, S., Irons, M., Sparagana, S., Williams, M., Phillips, J. A., Beaudet, A. L., Stankiewicz, P., Patel, A., Cheung, S. W. & 1 others, Sahoo, T., Mar 2010, In: American Journal of Medical Genetics, Part A. 152, 3, p. 573-581 9 p.

  Research output: Contribution to journal › Article › peer-review
  99 Scopus citations

• 22- S -Hydroxycholesterol protects against ethanol-induced liver injury by blocking the auto/paracrine activation of MCP-1 mediated by LXR α

  Na, T. Y., Han, Y. H., Ka, N. L., Park, H. S., Kang, Y. P., Kwon, S. W., Lee, B. H. & Lee, M. O., Apr 1 2015, In: Journal of Pathology. 235, 5, p. 710-720 11 p.

  Research output: Contribution to journal › Article › peer-review
  22 Scopus citations

• 22-year-old girl with status epilepticus and progressive neurological symptoms

  Striano, P., Ackerley, C. A., Cervasio, M., Girard, J. M., Turnbull, J., Del Basso-De Caro, M. L., Striano, S., Zara, F. & Minassian, B. A., Oct 2009, In: Brain Pathology. 19, 4, p. 727-730 4 p.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations