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20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism
Akbulut, T., Regner, K. R., Roman, R. J., Avner, E. D., Falck, J. R. & Park, F., Sep 2009, In: American Journal of Physiology - Renal Physiology. 297, 3, p. F662-F670Research output: Contribution to journal › Article › peer-review
44 Scopus citations -
20-HETE Activates the Transcription of Angiotensin-Converting Enzyme via Nuclear Factor-κB Translocation and Promoter Binding
Garcia, V., Shkolnik, B., Milhau, L., Falck, J. R. & Schwartzman, M. L., Mar 1 2016, In: Journal of Pharmacology and Experimental Therapeutics. 356, 3, p. 525-533 9 p.Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
20-HETE agonists and antagonists in the renal circulation
Alonso-Galicia, M., Falck, J. R., Reddy, K. M. & Roman, R. J., Nov 1999, In: American Journal of Physiology - Renal Physiology. 277, 5 46-5, p. F790-F796Research output: Contribution to journal › Article › peer-review
114 Scopus citations -
20-HETE and F2-isoprostanes in the metabolic syndrome: the effect of weight reduction
Tsai, I. J., Croft, K. D., Mori, T. A., Falck, J. R., Beilin, L. J., Puddey, I. B. & Barden, A. E., Jan 15 2009, In: Free Radical Biology and Medicine. 46, 2, p. 263-270 8 p.Research output: Contribution to journal › Article › peer-review
63 Scopus citations -
20-HETE can act as a nonhypoxic regulator of HIF-1α in human microvascular endothelial cells
Guo, A. M., Scicli, G., Sheng, J., Falck, J. C., Edwards, P. A. & Scicli, A. G., Aug 1 2009, In: American Journal of Physiology - Heart and Circulatory Physiology. 297, 2, p. H602-H613Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
20-HETE contributes to ischemia-induced angiogenesis
Chen, L., Joseph, G., Zhang, F. F., Nguyen, H., Jiang, H., Gotlinger, K. H., Falck, J. R., Yang, J., Schwartzman, M. L. & Guo, A. M., Aug 1 2016, In: Vascular Pharmacology. 83, p. 57-65 9 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
20-HETE contributes to myogenic activation of skeletal muscle resistance arteries in Brown Norway and Sprague-Dawley rats
Frisbee, J. C., Roman, R. J., Falck, J. R., Krishna, M. & Lombard, J. H., 2001, In: Microcirculation. 8, 1, p. 45-55 11 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
20-HETE increases superoxide production and activates NAPDH oxidase in pulmonary artery endothelial cells
Medhora, M., Chen, Y., Gruenloh, S., Harland, D., Bodiga, S., Zielonka, J., Gebremedhin, D., Gao, Y., Falck, J. R., Anjaiah, S. & Jacobs, E. R., May 2008, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 294, 5, p. L902-L911Research output: Contribution to journal › Article › peer-review
60 Scopus citations -
20-HETE increases survival and decreases apoptosis in pulmonary arteries and pulmonary artery endothelial cells
Dhanasekaran, A., Bodiga, S., Gruenloh, S., Gao, Y., Dunn, L., Falck, J. R., Buonaccorsi, J. N., Medhora, M. & Jacobs, E. R., Mar 2009, In: American Journal of Physiology - Heart and Circulatory Physiology. 296, 3, p. H777-H786Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
20-HETE-induced nitric oxide production in pulmonary artery endothelial cells is mediated by NADPH oxidase, H2O2, and PI3-kinase/Akt
Bodiga, S., Gruenloh, S. K., Gao, Y., Manthati, V. L., Dubasi, N., Falck, J. R., Medhora, M. & Jacobs, E. R., Apr 2010, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 298, 4, p. L564-L574Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
20-HETE induces remodeling of renal resistance arteries independent of blood pressure elevation in hypertension
Ding, Y., Wu, C. C., Garcia, V., Dimitrova, I., Weidenhammer, A., Joseph, G., Zhang, F., Manthati, V. L., Falck, J. R., Capdevila, J. H. & Schwartzman, M. L., Sep 1 2013, In: American Journal of Physiology - Renal Physiology. 305, 5, p. F753-F763Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
20-HETE interferes with insulin signaling and contributes to obesity-driven insulin resistance
Gilani, A., Agostinucci, K., Hossain, S., Pascale, J. V., Garcia, V., Adebesin, A. M., Falck, J. R. & Schwartzman, M. L., Feb 2021, In: Prostaglandins and Other Lipid Mediators. 152, 106485.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
20-HETE is an endogenous inhibitor of the large-conductance Ca2+-activated K+ channel in renal arterioles
Zou, A. P., Fleming, J. T., Falck, J. R., Jacobs, E. R., Gebremedhin, D., Harder, D. R. & Roman, R. J., 1996, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 270, 1 39-1, p. R228-R237Research output: Contribution to journal › Article › peer-review
277 Scopus citations -
20-HETE mediates the effect of parathyroid hormone and protein kinase C on renal phosphate transport
Silverstein, D. M., Barac-Nieto, M., Falck, J. R. & Spitzer, A., Mar 1998, In: Prostaglandins Leukotrienes and Essential Fatty Acids. 58, 3, p. 209-213 5 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
20-HETE modulates myogenic response of skeletal muscle resistance arteries from hypertensive Dahl-SS rats
Frisbee, J. C., Roman, R. J., Krishna, U. M., Falck, J. R. & Lombard, J. H., 2001, In: American Journal of Physiology - Heart and Circulatory Physiology. 280, 3 49-3, p. H1066-H1074Research output: Contribution to journal › Article › peer-review
39 Scopus citations -
20-HETE Participates in Intracerebral Hemorrhage-Induced Acute Injury by Promoting Cell Ferroptosis
Han, R., Wan, J., Han, X., Ren, H., Falck, J. R., Munnuri, S., Yang, Z. J. & Koehler, R. C., Nov 12 2021, In: Frontiers in Neurology. 12, 763419.Research output: Contribution to journal › Article › peer-review
Open Access -
20-HETE pathway antagonists inhibit rat small mesenteric artery tone
Looft-Wilson, R. C., Falck, J. R., Krishna, U. M. & Gisolfi, C. V., 2002, In: Microvascular Research. 64, 2, p. 349-352 4 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
20-HETE regulates the angiogenic functions of human endothelial progenitor cells and contributes to angiogenesis in vivo
Chen, L., Ackerman, R., Saleh, M., Gotlinger, K. H., Kessler, M., Mendelowitz, L. G., Falck, J. R., Arbab, A. S., Scicli, A. G., Schwartzman, M. L., Yang, J. & Guo, A. M., Mar 2014, In: Journal of Pharmacology and Experimental Therapeutics. 348, 3, p. 442-451 10 p.Research output: Contribution to journal › Article › peer-review
49 Scopus citations -
20-HETE Relaxes Bovine Coronary Arteries Through the Release of Prostacyclin
Pratt, P. F., Falck, J. R., Reddy, K. M., Kurian, J. B. & Campbell, W. B., Jan 1998, In: Hypertension. 31, 1, p. 237-241 5 p.Research output: Contribution to journal › Article › peer-review
Open Access38 Scopus citations -
20-HETE Signals Through G-Protein-Coupled Receptor GPR75 (Gq) to Affect Vascular Function and Trigger Hypertension
Garcia, V., Gilani, A., Shkolnik, B., Pandey, V., Zhang, F. F., Dakarapu, R., Gandham, S. K., Reddy, R. R., Graves, J. P., Gruzdev, A., Zeldin, D. C., Capdevila, J. H., Falck, J. R. & Schwartzman, M. L., May 26 2017, In: Circulation research. 120, 11, p. 1776-1788 13 p.Research output: Contribution to journal › Article › peer-review
67 Scopus citations -
20-HETE synthesis inhibition promotes cerebral protection after intracerebral hemorrhage without inhibiting angiogenesis
Han, X., Zhao, X., Lan, X., Li, Q., Gao, Y., Liu, X., Wan, J., Yang, Z., Chen, X., Zang, W., Guo, A. M., Falck, J. R., Koehler, R. C. & Wang, J., Aug 1 2019, In: Journal of Cerebral Blood Flow and Metabolism. 39, 8, p. 1531-1543 13 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
20-Hydroxy-5,8,11,14-eicosatetraenoic acid mediates endothelial dysfunction via IκB kinase-dependent endothelial nitric-oxide synthase uncoupling
Cheng, J., Wu, C. C., Gotlinger, K. H., Zhang, F., Falck, J. R., Narsimhaswamy, D. & Laniado-Schwartzman, M., Jan 2010, In: Journal of Pharmacology and Experimental Therapeutics. 332, 1, p. 57-65 9 p.Research output: Contribution to journal › Article › peer-review
73 Scopus citations -
20-Hydroxyeicosatetraenoic acid (20-HETE): Structural determinants for renal vasoconstriction
Yu, M., Alonso-Galicia, M., Sun, C. W., Roman, R. J., Ono, N., Hirano, H., Ishimoto, T., Reddy, Y. K., Katipally, K. R., Reddy, K. M., Gopal, V. R., Yu, J., Takhi, M. & Falck, J. R., Jul 3 2003, In: Bioorganic and Medicinal Chemistry. 11, 13, p. 2803-2821 19 p.Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
20-Hydroxyeicosatetraenoic Acid (20-HETE) Metabolism in Coronary Endothelial Cells
Kaduce, T. L., Fang, X., Harmon, S. D., Oltman, C. L., Dellsperger, K. C., Teesch, L. M., Gopal, V. R., Falck, J. R., Campbell, W. B., Weintraub, N. L. & Spector, A. A., Jan 23 2004, In: Journal of Biological Chemistry. 279, 4, p. 2648-2656 9 p.Research output: Contribution to journal › Article › peer-review
47 Scopus citations -
20-Hydroxyeicosatetraenoic acid (HETE)-dependent hypertension in human cytochrome P450 (CYP) 4A11 transgenic mice: Normalization of blood pressure by sodium restriction, hydrochlorothiazide, or blockade of the type 1 angiotensin II receptor
Savas, Ü., Wei, S., Hsu, M. H., Falck, J. R., Guengerich, F. P., Capdevila, J. H. & Johnson, E. F., Aug 5 2016, In: Journal of Biological Chemistry. 291, 32, p. 16904-16919 16 p.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: A study in Cyp1a1-Ren-2 transgenic rats
Sedláková, L., Kikerlová, S., Husková, Z., Červenková, L., Chábová, V. Č., Zicha, J., Falck, J. R., Imig, J. D., Kompanowska-Jezierska, E., Sadowski, J., Krátký, V., Červenka, L. & Kopkan, L., Sep 12 2018, In: Bioscience reports. 38, 5, BSR20171496.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
20-Hydroxyeicosatetraenoic acid causes endothelial dysfunction via eNOS uncoupling
Cheng, J., Ou, J. S., Singh, H., Falck, J. R., Narsimhaswamy, D., Pritchard, K. A. & Schwartzman, M. L., Feb 2008, In: American Journal of Physiology - Heart and Circulatory Physiology. 294, 2, p. H1018-H1026Research output: Contribution to journal › Article › peer-review
122 Scopus citations -
20-Hydroxyeicosatetraenoic acid contributes to the inhibition of K+ channel activity and vasoconstrictor response to angiotensin II in rat renal microvessels
Fan, F., Sun, C. W., Maier, K. G., Williams, J. M., Pabbidi, M. R., Didion, S. P., Falck, J. R., Zhuo, J. & Roman, R. J., Dec 4 2013, In: PloS one. 8, 12, e82482.Research output: Contribution to journal › Article › peer-review
42 Scopus citations -
20-Hydroxyeicosatetraenoic acid is an endogenous vasoconstrictor of canine renal arcuate arteries
Ma, Y. H., Gebremedhin, D., Schwartzman, M. L., Falck, J. R., Clark, J. E., Masters, B. S., Harder, D. R. & Roman, R. J., 1993, In: Circulation research. 72, 1, p. 126-136 11 p.Research output: Contribution to journal › Article › peer-review
Open Access245 Scopus citations -
20-Hydroxyeicosatetraenoic acid is an endothelium-dependent vasoconstrictor in rabbit arteries
Escalante, B., Omata, K., Sessa, W., Lee, S. G., Falck, J. R. & Schwartzman, M. L., Apr 22 1993, In: European Journal of Pharmacology. 235, 1, p. 1-7 7 p.Research output: Contribution to journal › Article › peer-review
65 Scopus citations -
20-Hydroxyeicosatetraenoic acid is a potent dilator of mouse basilar artery: Role of cyclooxygenase
Fang, X., Faraci, F. M., Kaduce, T. L., Harmon, S., Modrick, M. L., Hu, S., Moore, S. A., Falck, J. R., Weintraub, N. L. & Spector, A. A., 2006, In: American Journal of Physiology - Heart and Circulatory Physiology. 291, 5, p. H2301-H2307Research output: Contribution to journal › Article › peer-review
37 Scopus citations -
20-Hydroxyeicosatetraenoic acid is excreted as a glucuronide conjugate in human urine
Prakash, C., Zhang, J. Y., Falck, J. R., Chauhan, K. & Blair, I. A., Jun 15 1992, In: Biochemical and Biophysical Research Communications. 185, 2, p. 728-733 6 p.Research output: Contribution to journal › Article › peer-review
58 Scopus citations -
20-hydroxyeicosatetraenoic acid is formed in response to EGF and is a mitogen in rat proximal tubule
Lin, F., Rios, A., Falck, J. R., Belosludtsev, Y. & Schwartzman, M. L., 1995, In: American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 269, 6 38-6, p. F806-F816Research output: Contribution to journal › Article › peer-review
68 Scopus citations -
20-Hydroxyeicosatetraenoic acid is formed in response to EGF and is a mitogen in rat proximal tubule
Lin, F., Rios, A., Falck, J. R., Belosludtsev, Y. & Schwartzman, M. L., Dec 1 1995, In: American Journal of Physiology - Renal Physiology. 269, 6, p. F805-F816Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
20-Hydroxyeicosatetraenoic acid stimulates nuclear factor-κB activation and the production of inflammatory cytokines in human endothelial cells
Ishizuka, T., Cheng, J., Singh, H., Vitto, M. D., Manthati, V. L., Falck, J. R. & Laniado-Schwartzman, M., Jan 2008, In: Journal of Pharmacology and Experimental Therapeutics. 324, 1, p. 103-110 8 p.Research output: Contribution to journal › Article › peer-review
130 Scopus citations -
20-Iodo-14,15-epoxyeicosa-8(Z)-enoyl-3-azidophenylsulfonamide: Photoaffinity labeling of a 14,15-epoxyeicosatrienoic acid receptor
Chen, Y., Falck, J. R., Manthati, V. L., Jat, J. L. & Campbell, W. B., May 10 2011, In: Biochemistry. 50, 18, p. 3840-3848 9 p.Research output: Contribution to journal › Article › peer-review
42 Scopus citations -
20 of the most influential people in EMS. Part 2. Interview by Mike Taigman.
Eisenberg, M., Jones, D., Cason, D., Stults, K., Birnbaum, M., White, R. D., Safar, P., Boyd, D., Overton, J. & Mantooth, R., Aug 2000, In: JEMS : a journal of emergency medical services. 25, 8, p. 53-62 10 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
20-year experience with intraoperative high-dose-rate brachytherapy for pediatric sarcoma: Outcomes, toxicity, and practice recommendations
Folkert, M. R., Tong, W. Y., Laquaglia, M. P., Wexler, L. H., Chou, A. J., Magnan, H., Zelefsky, M. J. & Wolden, S. L., Oct 1 2014, In: International Journal of Radiation Oncology Biology Physics. 90, 2, p. 362-368 7 p.Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
20 years of Developmental Cell: Looking back
Chory, J., Olson, E. N., Solnica-Krezel, L., Munro, S., Fuchs, E., St. Johnston, D., Lefebvre, V., Coupland, G., Millar, S. E. & Lin, H., Dec 6 2021, In: Developmental cell. 56, 23, p. 3181-3184 4 p.Research output: Contribution to journal › Article › peer-review
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211th ENMC International Workshop:: Development of diagnostic criteria and management strategies for McArdle Disease and related rare glycogenolytic disorders to improve standards of care. 17–19 April 2015, Naarden, The Netherlands
Workshop Participants, Dec 2017, In: Neuromuscular Disorders. 27, 12, p. 1143-1151 9 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
218th ENMC International Workshop:: Revisiting the consensus on standards of care in SMA Naarden, The Netherlands, 19–21 February 2016
ENMC SMA Workshop Study Group, Jun 2017, In: Neuromuscular Disorders. 27, 6, p. 596-605 10 p.Research output: Contribution to journal › Article › peer-review
34 Scopus citations -
21st Century Advances in Multimodality Imaging of Obesity for Care of the Cardiovascular Patient
Neeland, I. J., Yokoo, T., Leinhard, O. D. & Lavie, C. J., Feb 2021, In: JACC: Cardiovascular Imaging. 14, 2, p. 482-494 13 p.Research output: Contribution to journal › Review article › peer-review
Open Access11 Scopus citations -
21st Century Cures Act: Implementation Without Understanding Implication?
Gerber, D. E., Feb 1 2022, In: JCO Oncology Practice. 18, 2, p. 85-87 3 p.Research output: Contribution to journal › Editorial › peer-review
Open Access -
225Ac-Prostate-Specific Membrane Antigen Therapy for Castration-Resistant Prostate Cancer: A Single-Center Experience
Sanli, Y., Kuyumcu, S., Simsek, D. H., Büyükkaya, F., Civan, C., Isik, E. G., Ozkan, Z. G., Basaran, M. & Sanli, O., Dec 1 2021, In: Clinical nuclear medicine. 46, 12, p. 943-951 9 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
22-Alkyl-20-epi-1α,25-dihydroxyvitamin D3 compounds of superagonistic activity: Syntheses, biological activities and interaction with the receptor
Yamamoto, K., Inaba, Y., Yoshimoto, N., Choi, M., DeLuca, H. F. & Yamada, S., Mar 8 2007, In: Journal of Medicinal Chemistry. 50, 5, p. 932-939 8 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
22nd Annual Carrell-Krusen Symposium. Dallas, Texas, USA. February 24-25, 2000. Abstracts
Iannaccone, S. T., Mar 2000, In: Journal of child neurology. 15, 3, p. 192-201 10 p.Research output: Contribution to journal › Article › peer-review
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22nd Marabou Symposium: The changing faces of vitamin D
James, P., Rosenberg, I., Mangelsdorf, D., DeLuca, H., Mathieu, C., Prentice, A., Meyer, H., Heaney, R., Holick, M., Garza, C., Moan, J., Angelin, B., Pedersen, J., Moskilde, L., Cross, H., Tuohimaa, P., Abrams, S., Campbell, M., Takasu, H., Haussler, M. & 4 others, , Oct 2008, In: Nutrition Reviews. 66, SUPPL.2, p. S195-S212Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
22q13.3 Deletion syndrome: Clinical and molecular analysis using array CGH
Dhar, S. U., Del Gaudio, D., German, J. R., Peters, S. U., Ou, Z., Bader, P. I., Berg, J. S., Blazo, M., Brown, C. W., Graham, B. H., Grebe, T. A., Lalani, S., Irons, M., Sparagana, S., Williams, M., Phillips, J. A., Beaudet, A. L., Stankiewicz, P., Patel, A., Cheung, S. W. & 1 others, , Mar 2010, In: American Journal of Medical Genetics, Part A. 152, 3, p. 573-581 9 p.Research output: Contribution to journal › Article › peer-review
99 Scopus citations -
22- S -Hydroxycholesterol protects against ethanol-induced liver injury by blocking the auto/paracrine activation of MCP-1 mediated by LXR α
Na, T. Y., Han, Y. H., Ka, N. L., Park, H. S., Kang, Y. P., Kwon, S. W., Lee, B. H. & Lee, M. O., Apr 1 2015, In: Journal of Pathology. 235, 5, p. 710-720 11 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
22-year-old girl with status epilepticus and progressive neurological symptoms
Striano, P., Ackerley, C. A., Cervasio, M., Girard, J. M., Turnbull, J., Del Basso-De Caro, M. L., Striano, S., Zara, F. & Minassian, B. A., Oct 2009, In: Brain Pathology. 19, 4, p. 727-730 4 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations