Find Research Outputs

2019

CASP13 target classification into tertiary structure prediction categories

Kinch, L. N., Kryshtafovych, A., Monastyrskyy, B. & Grishin, N. V., Jan 1 2019, In : Proteins: Structure, Function and Bioinformatics.

Research output: Contribution to journalArticle

Servers
Protein Databases
Cluster Analysis
Proteins
Topology
Nanoshells
Microbubbles
Silicon Dioxide
Catalase
Hydrogen Peroxide

Catalysis-dependent inactivation of human telomerase and its reactivation by intracellular telomerase-activating factors (iTAFs)

Sayed, M. E., Cheng, A., Yadav, G. P., Ludlow, A. T., Shay, J. W., Wright, W. E. & Jiang, Q. X., Jan 1 2019, In : Journal of Biological Chemistry. 294, 30, p. 11579-11596 18 p.

Research output: Contribution to journalArticle

Open Access
Telomerase
Catalysis
Catalytic Domain
Holoenzymes
Enzymes

Caution: Increased acute kidney injury in enhanced recovery after surgery (ERAS) protocols

Koerner, C. P., Lopez-Aguiar, A. G., Zaidi, M., Speegle, S., Balch, G. C., Shaffer, V. O., Staley, C. A., Srinivasan, J., Maithel, S. K. & Sullivan, P. S., Jan 1 2019, In : American Surgeon. 85, 2, p. 156-161 6 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Length of Stay
Colorectal Surgery
Morbidity
Mortality

Caveolin-1 as a pathophysiological factor and target in psoriasis

Kruglikov, I. L. & Scherer, P. E., Dec 1 2019, In : npj Aging and Mechanisms of Disease. 5, 1, 4.

Research output: Contribution to journalReview article

Open Access
Caveolin 1
Psoriasis
White Adipose Tissue
Mechanical Stress
Pharmacology

Cbl-PI3K interaction regulates Cathepsin K secretion in osteoclasts

Yu, J., Adapala, N. S., Doherty, L. & Sanjay, A., Oct 1 2019, In : Bone. 127, p. 376-385 10 p.

Research output: Contribution to journalArticle

Cathepsin K
Osteoclasts
Phosphatidylinositol 3-Kinases
Bone Resorption
Conditioned Culture Medium
3 Citations (Scopus)

CDK9: a signaling hub for transcriptional control

Bacon, C. W. & D'orso, I., Mar 15 2019, In : Transcription. 10, 2, p. 57-75 19 p.

Research output: Contribution to journalReview article

Cyclin-Dependent Kinase 9
Transcription
Elongation
Small Nucleolar RNA
Dichlororibofuranosylbenzimidazole

Celastrol reduces obesity in MC4R deficiency and stimulates sympathetic nerve activity affecting metabolic and cardiovascular functions

Berglund, E. D., Grobe, J. L., Rahmouni, K., Cui, H., Saito, K., Davis, K. C., Morgan, D. A., Toth, B. A., Jiang, J. & Singh, U., Jun 1 2019, In : Diabetes. 68, 6, p. 1210-1220 11 p.

Research output: Contribution to journalArticle

Receptor, Melanocortin, Type 4
Obesity
Endoplasmic Reticulum Stress
Body Weight
Leptin

Cell Cycle and Beyond: Exploiting New RB1 Controlled Mechanisms for Cancer Therapy

Knudsen, E. S., Pruitt, S. C., Hershberger, P. A., Witkiewicz, A. & Goodrich, D. W., Jan 1 2019, In : Trends in Cancer.

Research output: Contribution to journalReview article

Cell Cycle
Neoplasms
Therapeutics
Cyclin-Dependent Kinase 6
Cyclin-Dependent Kinase 4

Cell cycle plasticity driven by MTOR signaling: integral resistance to CDK4/6 inhibition in patient-derived models of pancreatic cancer

Knudsen, E. S., Kumarasamy, V., Ruiz, A., Sivinski, J., Chung, S., Grant, A., Vail, P., Chauhan, S. S., Jie, T., Riall, T. S. & Witkiewicz, A., Jan 1 2019, In : Oncogene.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Transcriptome
Cell Cycle
Adenocarcinoma
Cyclins
4 Citations (Scopus)

Cell-of-origin susceptibility to glioblastoma formation declines with neural lineage restriction

Alcantara Llaguno, S., Sun, D., Pedraza, A. M., Vera, E., Wang, Z., Burns, D. K. & Parada, L. F., Apr 1 2019, In : Nature neuroscience. 22, 4, p. 545-555 11 p.

Research output: Contribution to journalArticle

Glioblastoma
Neoplasms
Stem Cells
Neurons
Tamoxifen
3 Citations (Scopus)

Cell-Specific Loss of SNAP25 from Cortical Projection Neurons Allows Normal Development but Causes Subsequent Neurodegeneration

Hoerder-Suabedissen, A., Korrell, K. V., Hayashi, S., Jeans, A., Ramirez, D. M. O., Grant, E., Christian, H. C., Kavalali, E. T., Wilson, M. C. & Molnár, Z., May 1 2019, In : Cerebral cortex (New York, N.Y. : 1991). 29, 5, p. 2148-2159 12 p.

Research output: Contribution to journalArticle

Synaptosomal-Associated Protein 25
Synaptic Vesicles
Neurons
SNARE Proteins
Lipofuscin

Cells to Surgery Quiz: June 2019

Matsumoto, A. & Nijhawan, R. I., Jun 1 2019, In : Journal of Investigative Dermatology. 139, 6, p. e65-e70

Research output: Contribution to journalShort survey

Open Access
Surgery

Cells to Surgery Quiz: February 2019

Vatanchi, M. & Nijhawan, R. I., Feb 1 2019, In : Journal of Investigative Dermatology. 139, 2, p. e17-e21

Research output: Contribution to journalShort survey

Surgery
1 Citation (Scopus)

Cell type and receptor identity regulate cholera toxin subunit B (CTB) internalization

Sethi, A., Wands, A. M., Mettlen, M., Krishnamurthy, S., Wu, H. & Kohler, J. J., Apr 6 2019, In : Interface Focus. 9, 2, 20180076.

Research output: Contribution to journalArticle

Cholera Toxin
Cells
Glycoconjugates
Ports and harbors
G(M1) Ganglioside

Cell type-specific epigenetic links to schizophrenia risk in the brain

Mendizabal, I., Berto, S., Usui, N., Toriumi, K., Chatterjee, P., Douglas, C., Huh, I., Jeong, H., Layman, T., Tamminga, C. A., Preuss, T. M., Konopka, G. & Yi, S. V., Jul 9 2019, In : Genome Biology. 20, 1, 135.

Research output: Contribution to journalArticle

Open Access
Epigenomics
epigenetics
brain
Schizophrenia
methylation
2 Citations (Scopus)

Cellular signalling by primary cilia in development, organ function and disease

Anvarian, Z., Mykytyn, K., Mukhopadhyay, S., Pedersen, L. B. & Christensen, S. T., Apr 1 2019, In : Nature Reviews Nephrology. 15, 4, p. 199-219 21 p.

Research output: Contribution to journalReview article

Cilia
Cues
Signal Transduction
Homeostasis
Hedgehog Proteins

Central nervous system signatures of affect in asthma: Associations with emotion-induced bronchoconstriction, airway inflammation, and asthma control

Ritz, T., Kroll, J. L., Patel, S. V., Chen, J. R., Yezhuvath, U. S., Aslan, S., Khan, D. A., Pinkham, A. E., Rosenfield, D. & Brown, E. S., Jan 1 2019, In : Journal of applied physiology. 126, 6, p. 1725-1736 12 p.

Research output: Contribution to journalArticle

Bronchoconstriction
Emotions
Asthma
Central Nervous System
Inflammation

Cephalic Rotation of the Nasal Tip

Afrooz, P. N., Carboy, J. A., Mendez, B. M. & Rohrich, R. J., Apr 1 2019, In : Plastic and reconstructive surgery. 143, 4, p. 734e-743e

Research output: Contribution to journalArticle

Nose
Head
Cartilage
Rhinoplasty
Esthetics
1 Citation (Scopus)

Cephalosporin Allergy: Current Understanding and Future Challenges

Khan, D. A., Banerji, A., Bernstein, J. A., Bilgicer, B., Blumenthal, K., Castells, M., Ein, D., Lang, D. M. & Phillips, E., Jan 1 2019, In : Journal of Allergy and Clinical Immunology: In Practice.

Research output: Contribution to journalArticle

Cephalosporins
Hypersensitivity
Skin
Basophils
beta-Lactams
Open Access
Ventilator-Induced Lung Injury
Ceramides
Autophagy
Apoptosis
Therapeutics
8 Citations (Scopus)

Cerebellar ataxia disease-associated Snx14 promotes lipid droplet growth at ER-droplet contacts

Datta, S., Liu, Y., Hariri, H., Bowerman, J. & Henne, W. M., Apr 1 2019, In : The Journal of cell biology. 218, 4, p. 1335-1351 17 p.

Research output: Contribution to journalArticle

Open Access
Cerebellar Diseases
Cerebellar Ataxia
Endoplasmic Reticulum
Growth
Fatty Acids

Cerebellar syndrome in a man treated with natalizumab: From the National Multiple Sclerosis Society Case Conference Proceedings

Lapides, D. A., Batchala, P. P., Donahue, J. H., Lisak, R. P., Meltzer, E. I., Narayan, R. N., Nath, A., Frohman, T. C., Costello, K., Goldman, M. D., Zamvil, S. S. & Frohman, E., May 1 2019, In : Neurology: Neuroimmunology and NeuroInflammation. 6, 3, e546.

Research output: Contribution to journalArticle

Open Access
Cerebellar Diseases
Multiple Sclerosis
Natalizumab
1 Citation (Scopus)

Cerebral Blood Perfusion Predicts Response to Sertraline versus Placebo for Major Depressive Disorder in the EMBARC Trial

Cooper Cortes, C., Chin Fatt, C. R., Jha, M. K., Fonzo, G. A., Grannemann, B. D., Carmody, T. J., Ali, A., Aslan, S., Almeida, J. R. C., Deckersbach, T., Fava, M., Kurian, B. T., McGrath, P. J., McInnis, M., Parsey, R. V., Weissman, M., Phillips, M. L., Lu, H., Etkin, A. & Trivedi, M. H., Jan 1 2019, In : EClinicalMedicine.

Research output: Contribution to journalArticle

Open Access
Sertraline
Major Depressive Disorder
Perfusion
Placebos
Brain
1 Citation (Scopus)

Cerebral vasomotor reactivity during hypo- and hypercapnia across the adult lifespan

Tomoto, T., Riley, J., Turner, M., Zhang, R. & Tarumi Ph.D., T., Jan 1 2019, In : Journal of Cerebral Blood Flow and Metabolism.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Hypocapnia
Blood Flow Velocity
Hypercapnia
Carbon Monoxide
1 Citation (Scopus)

cGAS activation causes lupus-like autoimmune disorders in a TREX1 mutant mouse model

Xiao, N., Wei, J., Xu, S., Du, H., Huang, M., Zhang, S., Ye, W., Sun, L. & Chen, Q., Jun 1 2019, In : Journal of Autoimmunity. 100, p. 84-94 11 p.

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
Genes
Autoimmune Diseases
Exodeoxyribonucleases
Inflammation
10 Citations (Scopus)

cGAS in action: Expanding roles in immunity and inflammation

Ablasser, A. & Chen, Z., Mar 8 2019, In : Science (New York, N.Y.). 363, 6431

Research output: Contribution to journalReview article

Immunity
Inflammation
DNA
Infection
Therapeutics

Challenges associated with treatment of left internal mammary artery graft thrombosis

Xenogiannis, I., Vemmou, E., Nikolakopoulos, I. & Brilakis, E. S., Jan 1 2019, In : Catheterization and Cardiovascular Interventions.

Research output: Contribution to journalArticle

Mammary Arteries
Coronary Artery Bypass
Thrombectomy
Thrombosis
Transplants

Challenges encountered using Fassier-Duval rods in osteogenesis imperfect

Landrum, M., Birch, C. & Richards, B. S., Jul 1 2019, In : Current Orthopaedic Practice. 30, 4, p. 318-322 5 p.

Research output: Contribution to journalArticle

Telescopes
Osteogenesis Imperfecta
Osteogenesis
Bone and Bones
Equipment and Supplies
2 Citations (Scopus)

Challenges for the Clinical Development of PI3K Inhibitors: Strategies to Improve Their Impact in Solid Tumors

Hanker, A. B., Kaklamani, V. & Arteaga, C. L., Apr 1 2019, In : Cancer discovery. 9, 4, p. 482-491 10 p.

Research output: Contribution to journalReview article

Phosphatidylinositol 3-Kinases
Neoplasms
Drug-Related Side Effects and Adverse Reactions
Patient Selection
Cell Survival

Challenges in Implementing Optimal Echocardiographic Screening in Cardio-Oncology

McDonald, J. P., MacNamara, J. P. & Zaha, V., Aug 1 2019, In : Current Treatment Options in Cardiovascular Medicine. 21, 8, 39.

Research output: Contribution to journalReview article

Costs and Cost Analysis
Cardiology
Echocardiography
Cardiotoxins
Point-of-Care Systems
Adenocarcinoma
Papanicolaou Test
Cell Biology
Adenocarcinoma in Situ
13 Citations (Scopus)

Change in albuminuria as a surrogate endpoint for progression of kidney disease: a meta-analysis of treatment effects in randomised clinical trials

Chronic Kidney Disease Epidemiology Collaboration, Feb 1 2019, In : The Lancet Diabetes and Endocrinology. 7, 2, p. 128-139 12 p.

Research output: Contribution to journalArticle

Albuminuria
Kidney Diseases
Meta-Analysis
Randomized Controlled Trials
Biomarkers

Changing Times in Liver Transplantation for Alcohol-Associated Liver Disease

Mitchell, M. C. & Maddrey, W. C., Jan 1 2019, (Accepted/In press) In : JAMA Internal Medicine.

Research output: Contribution to journalArticle

Liver Transplantation
Liver Diseases
Alcohols

CHAPTER 2: Mechanisms of Antisense Oligonucleotides

Liu, Z. & Corey, D. R., Jan 1 2019, Therapies for Retinal Degeneration: Targeting Common Processes. Agrawal, S. & Gait, M. J. (eds.). 68 ed. Royal Society of Chemistry, p. 22-31 10 p. (RSC Drug Discovery Series; vol. 2019-January, no. 68).

Research output: Chapter in Book/Report/Conference proceedingChapter

Antisense Oligonucleotides
RNA Cleavage
Ribonuclease H
Alternative Splicing
Protein Biosynthesis

Characteristics and Outcome in Children With Craniectomy Following Acute Ischemic Stroke in the International Pediatric Stroke Study

on behalf of the International Pediatric Stroke Study Investigators, Jan 1 2019, In : Journal of child neurology.

Research output: Contribution to journalArticle

Stroke
Pediatrics
Intracranial Thrombosis
Middle Cerebral Artery Infarction
Decompression
Hospital Emergency Service
Hospitalization
Safety
Health
Neoplasms
1 Citation (Scopus)

Characteristics of graduating US allopathic medical students pursuing a career in neurology

Gutmann, L., Cahill, C., Jordan, J. T., Gamaldo, C. E., Santini, V., Ali, I., Soni, M., Wilson, R. B., Said, R. R., Czeisler, B. M. & Smith, A. G., Apr 23 2019, In : Neurology. 92, 17, p. e2051-e2063

Research output: Contribution to journalArticle

Neurology
Medical Students
Students
Neurosciences
Salaries and Fringe Benefits

Characterization and Trajectory of Coronary Artery Calcium Percentiles: The Dallas Heart Study

Eades, M. T., Paixao, A. R. M., Mehta, A., Ayers, C. R., Joshi, P., Berry, J. D., de Lemos, J. A. & Khera, A., Jul 1 2019, In : JACC: Cardiovascular Imaging. 12, 7, p. 1290-1292 3 p.

Research output: Contribution to journalLetter

Coronary Vessels
Calcium

Characterization of cortical and subcortical abnormalities in drug-naive boys with attention-deficit/hyperactivity disorder

Lu, L., Zhang, L., Tang, S., Bu, X., Chen, Y., Hu, X., Hu, X., Li, H., Guo, L., Sweeney, J. A., Gong, Q. & Huang, X., May 1 2019, In : Journal of Affective Disorders. 250, p. 397-403 7 p.

Research output: Contribution to journalArticle

Attention Deficit Disorder with Hyperactivity
Frontal Lobe
Pharmaceutical Preparations
Putamen
Linear Models

Characterization of Dizziness After Lasmiditan Usage: Findings From the SAMURAI and SPARTAN Acute Migraine Treatment Randomized Trials

Tepper, S. J., Krege, J. H., Lombard, L., Asafu-Adjei, J. K., Dowsett, S. A., Raskin, J., Buchanan, A. S. & Friedman, D. I., Jul 1 2019, In : Headache. 59, 7, p. 1052-1062 11 p.

Research output: Contribution to journalArticle

Dizziness
Migraine Disorders
Placebos
Therapeutics
Pain

Checkpoint Inhibitor Pneumonitis: Too Clinically Serious For Benefit?

Le, T., Minna, J. D. & Gerber, D. E., Mar 1 2019, In : Journal of Thoracic Oncology. 14, 3, p. 332-335 4 p.

Research output: Contribution to journalEditorial

Pneumonia

Chemobrain: A Pilot Study Exploring the Severity and Onset of Chemotherapy-Related Cognitive Impairment

Moore, K., Stutzman, S., Priddy, L. & Olson, D., Aug 1 2019, In : Clinical journal of oncology nursing. 23, 4, p. 411-416 6 p.

Research output: Contribution to journalArticle

Trail Making Test
Drug Therapy
Neurobehavioral Manifestations
Feasibility Studies
General Practitioners
2 Citations (Scopus)

Childhood trauma history is linked to abnormal brain connectivity in major depression

Yu, M., Linn, K. A., Shinohara, R. T., Oathes, D. J., Cook, P. A., Duprat, R., Moore, T. M., Oquendo, M. A., Phillips, M. L., McInnis, M., Fava, M., Trivedi, M. H., McGrath, P., Parsey, R., Weissman, M. M. & Sheline, Y. I., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 17, p. 8582-8590 9 p.

Research output: Contribution to journalArticle

Open Access
Major Depressive Disorder
Depression
Wounds and Injuries
Brain
Biomarkers

Chromatin Decondensation by FOXP2 Promotes Human Neuron Maturation and Expression of Neurodevelopmental Disease Genes

Hickey, S. L., Berto, S. & Konopka, G., May 7 2019, In : Cell Reports. 27, 6, p. 1699-1711.e9

Research output: Contribution to journalArticle

Open Access
Neurons
Chromatin
Genes
Brain
Aptitude
1 Citation (Scopus)

Chronic burn wound treatment by Erbium: YAG fractional ablation: First described report and literature review

Madni, T. D., Lu, K. B., Imran, J. B., Clark, A. T., Hoopman, J. E., Kenkel, J. M. & Phelan, H., Feb 1 2019, In : Burns. 45, 1, p. 256-258 3 p.

Research output: Contribution to journalLetter

Erbium
Wounds and Injuries

Chronic Pancreatitis: Pediatric and Adult Cohorts Show Similarities in Disease Progress Despite Different Risk Factors

Schwarzenberg, S. J., Uc, A., Zimmerman, B., Wilschanski, M., Wilcox, C. M., Whitcomb, D. C., Werlin, S. L., Troendle, D. M., Tang, G., Slivka, A., Singh, V. K., Sherman, S., Shah, U., Sandhu, B. S., Romagnuolo, J., Rhee, S., Pohl, J. F., Perito, E. R., Ooi, C. Y., Nathan, J. D. & 33 others, Muniraj, T., Morinville, V. D., McFerron, B., Mascarenhas, M., Maqbool, A., Liu, Q., Lin, T. K., Lewis, M., Husain, S. Z., Himes, R., Heyman, M. B., Guda, N., Gonska, T., Giefer, M. J., Gelrud, A., Gariepy, C. E., Gardner, T. B., Freedman, S. D., Forsmark, C. E., Fishman, D. S., Cote, G. A., Conwell, D., Brand, R. E., Bellin, M., Barth, B. A., Banks, P. A., Anderson, M. A., Amann, S. T., Alkaade, S., Abu-El-Haija, M., Abberbock, J. N., Lowe, M. E. & Yadav, D., Apr 1 2019, In : Journal of pediatric gastroenterology and nutrition. 68, 4, p. 566-573 8 p.

Research output: Contribution to journalArticle

Chronic Pancreatitis
Pediatrics
Pancreatitis
Alcohols
Demography

Chronic total occlusion percutaneous coronary intervention failure: Learning from failure

Karatasakis, A. & Brilakis, E. S., May 1 2019, In : Catheterization and Cardiovascular Interventions. 93, 6, p. 1039-1040 2 p.

Research output: Contribution to journalEditorial

Percutaneous Coronary Intervention
Learning
1 Citation (Scopus)

Citrate therapy for calcium phosphate stones

Rimer, J. D., Sakhaee, K. & Maalouf, N. M., Mar 1 2019, In : Current opinion in nephrology and hypertension. 28, 2, p. 130-139 10 p.

Research output: Contribution to journalArticle

Citric Acid
Crystallization
Therapeutics
Nephrolithiasis
Alkalies
2 Citations (Scopus)

C-Kit Cells Do Not Significantly Contribute to Cardiomyogenesis During Neonatal Heart Regeneration

Elhelaly, W. M., Cardoso, A. C., Pereira, A. H. M., Elnawasany, A., Ebrahimi, S., Nakada, Y. & Sadek, H. A., Jan 22 2019, In : Circulation. 139, 4, p. 559-561 3 p.

Research output: Contribution to journalLetter

Muscle Cells
Regeneration
afimoxifene