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20-HETE Signals Through G-Protein-Coupled Receptor GPR75 (Gq) to Affect Vascular Function and Trigger Hypertension

Garcia, V., Gilani, A., Shkolnik, B., Pandey, V., Zhang, F. F., Dakarapu, R., Gandham, S. K., Reddy, R. R., Graves, J. P., Gruzdev, A., Zeldin, D. C., Capdevila, J. H., Falck, J. R. & Schwartzman, M. L., May 26 2017, In : Circulation research. 120, 11, p. 1776-1788 13 p.

Research output: Contribution to journalArticle

38 Scopus citations

20-HETE synthesis inhibition promotes cerebral protection after intracerebral hemorrhage without inhibiting angiogenesis

Han, X., Zhao, X., Lan, X., Li, Q., Gao, Y., Liu, X., Wan, J., Yang, Z., Chen, X., Zang, W., Guo, A. M., Falck, J. R., Koehler, R. C. & Wang, J., Aug 1 2019, In : Journal of Cerebral Blood Flow and Metabolism. 39, 8, p. 1531-1543 13 p.

Research output: Contribution to journalArticle

16 Scopus citations

20-Hydroxy-5,8,11,14-eicosatetraenoic acid mediates endothelial dysfunction via IκB kinase-dependent endothelial nitric-oxide synthase uncoupling

Cheng, J., Wu, C. C., Gotlinger, K. H., Zhang, F., Falck, J. R., Narsimhaswamy, D. & Laniado-Schwartzman, M., Jan 1 2010, In : Journal of Pharmacology and Experimental Therapeutics. 332, 1, p. 57-65 9 p.

Research output: Contribution to journalArticle

65 Scopus citations

20-Hydroxyeicosatetraenoic acid (20-HETE): Structural determinants for renal vasoconstriction

Yu, M., Alonso-Galicia, M., Sun, C. W., Roman, R. J., Ono, N., Hirano, H., Ishimoto, T., Reddy, Y. K., Katipally, K. R., Reddy, K. M., Gopal, V. R., Yu, J., Takhi, M. & Falck, J. R., Jul 3 2003, In : Bioorganic and Medicinal Chemistry. 11, 13, p. 2803-2821 19 p.

Research output: Contribution to journalArticle

26 Scopus citations

20-Hydroxyeicosatetraenoic Acid (20-HETE) Metabolism in Coronary Endothelial Cells

Kaduce, T. L., Fang, X., Harmon, S. D., Oltman, C. L., Dellsperger, K. C., Teesch, L. M., Gopal, V. R., Falck, J. R., Campbell, W. B., Weintraub, N. L. & Spector, A. A., Jan 23 2004, In : Journal of Biological Chemistry. 279, 4, p. 2648-2656 9 p.

Research output: Contribution to journalArticle

45 Scopus citations
19 Scopus citations

20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: A study in Cyp1a1-Ren-2 transgenic rats

Sedláková, L., Kikerlová, S., Husková, Z., Červenková, L., Chábová, V. Č., Zicha, J., Falck, J. R., Imig, J. D., Kompanowska-Jezierska, E., Sadowski, J., Krátký, V., Červenka, L. & Kopkan, L., Sep 12 2018, In : Bioscience reports. 38, 5, BSR20171496.

Research output: Contribution to journalArticle

1 Scopus citations

20-Hydroxyeicosatetraenoic acid causes endothelial dysfunction via eNOS uncoupling

Cheng, J., Ou, J. S., Singh, H., Falck, J. R., Narsimhaswamy, D., Pritchard, K. A. & Schwartzman, M. L., Feb 2008, In : American Journal of Physiology - Heart and Circulatory Physiology. 294, 2, p. H1018-H1026

Research output: Contribution to journalArticle

113 Scopus citations

20-Hydroxyeicosatetraenoic acid contributes to the inhibition of K+ channel activity and vasoconstrictor response to angiotensin II in rat renal microvessels

Fan, F., Sun, C. W., Maier, K. G., Williams, J. M., Pabbidi, M. R., Didion, S. P., Falck, J. R., Zhuo, J. & Roman, R. J., Dec 4 2013, In : PloS one. 8, 12, e82482.

Research output: Contribution to journalArticle

31 Scopus citations

20-Hydroxyeicosatetraenoic acid is an endogenous vasoconstrictor of canine renal arcuate arteries

Ma, Y. H., Gebremedhin, D., Schwartzman, M. L., Falck, J. R., Clark, J. E., Masters, B. S., Harder, D. R. & Roman, R. J., 1993, In : Circulation research. 72, 1, p. 126-136 11 p.

Research output: Contribution to journalArticle

Open Access
239 Scopus citations

20-Hydroxyeicosatetraenoic acid is an endothelium-dependent vasoconstrictor in rabbit arteries

Escalante, B., Omata, K., Sessa, W., Lee, S. G., Falck, J. R. & Schwartzman, M. L., Apr 22 1993, In : European Journal of Pharmacology. 235, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

63 Scopus citations

20-Hydroxyeicosatetraenoic acid is a potent dilator of mouse basilar artery: Role of cyclooxygenase

Fang, X., Faraci, F. M., Kaduce, T. L., Harmon, S., Modrick, M. L., Hu, S., Moore, S. A., Falck, J. R., Weintraub, N. L. & Spector, A. A., 2006, In : American Journal of Physiology - Heart and Circulatory Physiology. 291, 5, p. H2301-H2307

Research output: Contribution to journalArticle

35 Scopus citations

20-Hydroxyeicosatetraenoic acid is excreted as a glucuronide conjugate in human urine

Prakash, C., Zhang, J. Y., Falck, J. R., Chauhan, K. & Blair, I. A., Jun 15 1992, In : Biochemical and Biophysical Research Communications. 185, 2, p. 728-733 6 p.

Research output: Contribution to journalArticle

57 Scopus citations

20-hydroxyeicosatetraenoic acid is formed in response to EGF and is a mitogen in rat proximal tubule

Lin, F., Rios, A., Falck, J. R., Belosludtsev, Y. & Schwartzman, M. L., 1995, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 269, 6 38-6, p. F806-F816

Research output: Contribution to journalArticle

68 Scopus citations

20-Hydroxyeicosatetraenoic acid is formed in response to EGF and is a mitogen in rat proximal tubule

Lin, F., Rios, A., Falck, J. R., Belosludtsev, Y. & Schwartzman, M. L., Dec 1 1995, In : American Journal of Physiology - Renal Physiology. 269, 6, p. F805-F816

Research output: Contribution to journalArticle

7 Scopus citations

20-Hydroxyeicosatetraenoic acid stimulates nuclear factor-κB activation and the production of inflammatory cytokines in human endothelial cells

Ishizuka, T., Cheng, J., Singh, H., Vitto, M. D., Manthati, V. L., Falck, J. R. & Laniado-Schwartzman, M., Jan 1 2008, In : Journal of Pharmacology and Experimental Therapeutics. 324, 1, p. 103-110 8 p.

Research output: Contribution to journalArticle

109 Scopus citations

20-Iodo-14,15-epoxyeicosa-8(Z)-enoyl-3-azidophenylsulfonamide: Photoaffinity labeling of a 14,15-epoxyeicosatrienoic acid receptor

Chen, Y., Falck, J. R., Manthati, V. L., Jat, J. L. & Campbell, W. B., May 10 2011, In : Biochemistry. 50, 18, p. 3840-3848 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

20 of the most influential people in EMS. Part 2. Interview by Mike Taigman.

Eisenberg, M., Jones, D., Cason, D., Stults, K., Birnbaum, M., White, R. D., Safar, P., Boyd, D., Overton, J. & Mantooth, R., Aug 2000, In : JEMS : a journal of emergency medical services. 25, 8, p. 53-62 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

20-year experience with intraoperative high-dose-rate brachytherapy for pediatric sarcoma: Outcomes, toxicity, and practice recommendations

Folkert, M. R., Tong, W. Y., Laquaglia, M. P., Wexler, L. H., Chou, A. J., Magnan, H., Zelefsky, M. J. & Wolden, S. L., Oct 1 2014, In : International Journal of Radiation Oncology Biology Physics. 90, 2, p. 362-368 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

218th ENMC International Workshop:: Revisiting the consensus on standards of care in SMA Naarden, The Netherlands, 19–21 February 2016

ENMC SMA Workshop Study Group, Jun 1 2017, In : Neuromuscular Disorders. 27, 6, p. 596-605 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

22-Alkyl-20-epi-1α,25-dihydroxyvitamin D3 compounds of superagonistic activity: Syntheses, biological activities and interaction with the receptor

Yamamoto, K., Inaba, Y., Yoshimoto, N., Choi, M., DeLuca, H. F. & Yamada, S., Mar 8 2007, In : Journal of Medicinal Chemistry. 50, 5, p. 932-939 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

22nd Annual Carrell-Krusen Symposium. Dallas, Texas, USA. February 24-25, 2000. Abstracts

Iannaccone, S. T., Mar 2000, In : Journal of child neurology. 15, 3, p. 192-201 10 p.

Research output: Contribution to journalArticle

22nd Marabou Symposium: The changing faces of vitamin D

James, P., Rosenberg, I., Mangelsdorf, D., DeLuca, H., Mathieu, C., Prentice, A., Meyer, H., Heaney, R., Holick, M., Garza, C., Moan, J., Angelin, B., Pedersen, J., Moskilde, L., Cross, H., Tuohimaa, P., Abrams, S., Campbell, M., Takasu, H., Haussler, M. & 4 others, Sitrin, M., Cantorna, M., Hernell, O. & Lamberg-Allardt, C., Oct 1 2008, In : Nutrition Reviews. 66, SUPPL.2, p. S195-S212

Research output: Contribution to journalArticle

6 Scopus citations

22q13.3 Deletion syndrome: Clinical and molecular analysis using array CGH

Dhar, S. U., Del Gaudio, D., German, J. R., Peters, S. U., Ou, Z., Bader, P. I., Berg, J. S., Blazo, M., Brown, C. W., Graham, B. H., Grebe, T. A., Lalani, S., Irons, M., Sparagana, S., Williams, M., Phillips, J. A., Beaudet, A. L., Stankiewicz, P., Patel, A., Cheung, S. W. & 1 others, Sahoo, T., Mar 2010, In : American Journal of Medical Genetics, Part A. 152, 3, p. 573-581 9 p.

Research output: Contribution to journalArticle

89 Scopus citations

22- S -Hydroxycholesterol protects against ethanol-induced liver injury by blocking the auto/paracrine activation of MCP-1 mediated by LXR α

Na, T. Y., Han, Y. H., Ka, N. L., Park, H. S., Kang, Y. P., Kwon, S. W., Lee, B. H. & Lee, M. O., Apr 1 2015, In : Journal of Pathology. 235, 5, p. 710-720 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

22-year-old girl with status epilepticus and progressive neurological symptoms

Striano, P., Ackerley, C. A., Cervasio, M., Girard, J. M., Turnbull, J., Del Basso-De Caro, M. L., Striano, S., Zara, F. & Minassian, B. A., Oct 2009, In : Brain Pathology. 19, 4, p. 727-730 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

23-hour observation solely for identification of missed injuries after trauma: is it justified?

Stephan, P. J., McCarley, M. C., O'Keefe, G. E. & Minei, J. P., Nov 2002, In : Journal of Trauma. 53, 5, p. 895-900 6 p.

Research output: Contribution to journalArticle

27 Scopus citations

24-hour and 30-day perioperative mortality in pediatric surgery

Bonasso, P. C., Dassinger, M. S., Ryan, M. L., Gowen, M. S., Burford, J. M. & Smith, S. D., Apr 2019, In : Journal of Pediatric Surgery. 54, 4, p. 628-630 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

24-Hour urine calcium in the evaluation and management of nephrolithiasis

Song, L. & Maalouf, N. M., Aug 1 2017, In : JAMA - Journal of the American Medical Association. 318, 5, p. 474-475 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

250 robotic pancreatic resections safety and feasibility

Zureikat, A. H., Moser, A. J., Boone, B. A., Bartlett, D. L., Zenati, M. & Zeh, H. J., Oct 2013, In : Annals of surgery. 258, 4, p. 554-559 6 p.

Research output: Contribution to journalArticle

198 Scopus citations

2564 resected periampullary adenocarcinomas at a single institution: Trends over three decades

He, J., Ahuja, N., Makary, M. A., Cameron, J. L., Eckhauser, F. E., Choti, M. A., Hruban, R. H., Pawlik, T. M. & Wolfgang, C. L., Jan 2014, In : HPB. 16, 1, p. 83-90 8 p.

Research output: Contribution to journalArticle

121 Scopus citations

25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages

Shibata, N., Carlin, A. F., Spann, N. J., Saijo, K., Morello, C. S., McDonald, J. G., Romanoski, C. E., Maurya, M. R., Kaikkonen, M. U., Lam, M. T., Crotti, A., Reichart, D., Fox, J. N., Quehenberger, O., Raetz, C. R. H., Cameron Sullards, M., Murphy, R. C., Merrill, A. H., Alex Brown, H., Dennis, E. A. & 6 others, Fahy, E., Subramaniam, S., Cavener, D. R., Spector, D. H., Russell, D. W. & Glassa, C. K., Dec 13 2013, In : Journal of Biological Chemistry. 288, 50, p. 35812-35823 12 p.

Research output: Contribution to journalArticle

32 Scopus citations

25-hydroxycholesterol contributes to cerebral inflammation of X-linked adrenoleukodystrophy through activation of the NLRP3 inflammasome

Jang, J., Park, S., Jin Hur, H., Cho, H. J., Hwang, I., Pyo Kang, Y., Im, I., Lee, H., Lee, E., Yang, W., Kang, H. C., Won Kwon, S., Yu, J. W. & Kim, D. W., Oct 25 2016, In : Nature communications. 7, 13129.

Research output: Contribution to journalArticle

57 Scopus citations
190 Scopus citations

25-hydroxycholesterol suppresses interleukin-1-driven inflammation downstream of type I interferon

Reboldi, A., Dang, E. V., McDonald, J. G., Liang, G., Russell, D. W. & Cyster, J. G., Aug 8 2014, In : Science. 345, 6197, p. 679-684 6 p.

Research output: Contribution to journalArticle

203 Scopus citations

25-Hydroxyvitamin D deficiency is a risk factor for symptoms of postoperative hypocalcemia and secondary hyperparathyroidism after minimally invasive parathyroidectomy

Stewart, Z. A., Blackford, A., Somervell, H., Friedman, K., Garrett-Mayer, E., Dackiw, A. P. B., Zeiger, M. A., Inabnet, W. B., Heller, K. S., Gaz, R. D., Pasieka, J. L. & Milas, K., Dec 1 2005, In : Surgery. 138, 6, p. 1018-1026 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

25-hydroxyvitamin D levels in African-American and Caucasian/Hispanic subjects with cutaneous lupus erythematosus

Word, A. P., Perese, F., Tseng, L. C., Adams-Huet, B., Olsen, N. J. & Chong, B. F., 2012, In : British Journal of Dermatology. 166, 2, p. 372-379 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

25-vitamin D levels in chronic hepatitis C infection: Association with cirrhosis and sustained virologic response

Backstedt, D., Pedersen, M., Choi, M. & Seetharam, A., Jan 1 2017, In : Annals of Gastroenterology. 30, 3, p. 344-348 5 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

26. Neural mechanisms of age-related changes in human working memory

Rypma, B., Berger, J. S. & D'Esposito, M., Dec 1 2001, In : Brain and Cognition. 47, 1-2, p. 113-116 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

26 S proteasome-mediated production of an authentic major histocompatibility class I-restricted epitope from an intact protein substrate

Ben-Shahar, S., Komlosh, A., Nadav, E., Shaked, I., Ziv, T., Admon, A., DeMartino, G. N. & Reiss, Y., Jul 30 1999, In : Journal of Biological Chemistry. 274, 31, p. 21963-21972 10 p.

Research output: Contribution to journalArticle

48 Scopus citations
187 Scopus citations

27-Hydroxycholesterol, an Endogenous SERM, and Risk of Fracture in Postmenopausal Women: A Nested Case-Cohort Study in the Women's Health Initiative

Chang, P. Y., Feldman, D., Stefanick, M. L., McDonnell, D. P., Thompson, B. M., McDonald, J. G. & Lee, J. S., Jan 2019, In : Journal of Bone and Mineral Research. 34, 1, p. 59-66 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
11 Scopus citations

27-Hydroxycholesterol is an endogenous selective estrogen receptor modulator

DuSell, C. D., Umetani, M., Shaul, P. W., Mangelsdorf, D. J. & McDonnell, D. P., Jan 2008, In : Molecular Endocrinology. 22, 1, p. 65-77 13 p.

Research output: Contribution to journalArticle

165 Scopus citations

27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen

Umetani, M., Domoto, H., Gormley, A. K., Yuhanna, I. S., Cummins, C. L., Javitt, N. B., Korach, K. S., Shaul, P. W. & Mangelsdorf, D. J., Oct 2007, In : Nature medicine. 13, 10, p. 1185-1192 8 p.

Research output: Contribution to journalArticle

249 Scopus citations

27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology

Nelson, E. R., Wardell, S. E., Jasper, J. S., Park, S., Suchindran, S., Howe, M. K., Carver, N. J., Pillai, R. V., Sullivan, P. M., Sondhi, V., Umetani, M., Geradts, J. & McDonnell, D. P., 2013, In : Science. 342, 6162, p. 1094-1098 5 p.

Research output: Contribution to journalArticle

375 Scopus citations

27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth

Wu, Q., Ishikawa, T., Sirianni, R., Tang, H., McDonald, J. G., Yuhanna, I. S., Thompson, B., Girard, L., Mineo, C., Brekken, R. A., Umetani, M., Euhus, D. M., Xie, Y. & Shaul, P. W., Nov 8 2013, In : Cell Reports. 5, 3, p. 637-645 9 p.

Research output: Contribution to journalArticle

175 Scopus citations

29 Combining gnotobiotic mouse models with functional genomics to define the impact of the microflora on host physiology

Hooper, L. V., Mills, J. C., Roth, K. A., Stappenbeck, T. S., Wong, M. H. & Gordon, J. I., 2002, In : Methods in Microbiology. 31, p. 559-589 31 p.

Research output: Contribution to journalArticle

29 Scopus citations

2A3 and 3F9: Novel lung epithelial antigens with early upregulation in hyperoxic and radiation lung injury models

Girod, C. E., Shin, D. H., Hershenson, M. B., Solway, J., Redlich, C. A., Gilman, L. B. & Miller, Y. E., Dec 1 1996, In : CHEST. 109, 3 SUPPL., p. 33S

Research output: Contribution to journalArticle