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2-Amino-2,3-dihydro-1 H-indene-5-carboxamide-Based Discoidin Domain Receptor 1 (DDR1) Inhibitors: Design, Synthesis, and in Vivo Antipancreatic Cancer Efficacy

Zhu, D., Huang, H., Pinkas, D. M., Luo, J., Ganguly, D., Fox, A. E., Arner, E., Xiang, Q., Tu, Z. C., Bullock, A. N., Brekken, R. A., Ding, K. & Lu, X., Aug 22 2019, In : Journal of Medicinal Chemistry. 62, 16, p. 7431-7444 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

2-Aminoadipic acid is a biomarker for diabetes risk

Wang, T. J., Ngo, D., Psychogios, N., Dejam, A., Larson, M. G., Vasan, R. S., Ghorbani, A., O'Sullivan, J., Cheng, S., Rhee, E. P., Sinha, S., McCabe, E., Fox, C. S., O'Donnell, C. J., Ho, J. E., Florez, J. C., Magnusson, M., Pierce, K. A., Souza, A. L., Yu, Y. & 5 others, Carter, C., Light, P. E., Melander, O., Clish, C. B. & Gerszten, R. E., Oct 1 2013, In : Journal of Clinical Investigation. 123, 10, p. 4309-4317 9 p.

Research output: Contribution to journalArticle

Open Access
194 Scopus citations

2-Arachidonoylglycerol: A novel inhibitor of androgen-independent prostate cancer cell invasion

Nithipatikom, K., Endsley, M. P., Isbell, M. A., Falck, J. R., Iwamoto, Y., Hillard, C. J. & Campbell, W. B., Dec 15 2004, In : Cancer research. 64, 24, p. 8826-8830 5 p.

Research output: Contribution to journalArticle

100 Scopus citations

2B4, a new member of the immunoglobulin gene superfamily, is expressed on murine dendritic epidermal T cells and plays a functional role in their killing of skin tumors

Schuhmachers, G., Ariizumi, K., Mathew, P. A., Bennett, M., Kumar, V. & Takashima, A., Jan 1 1995, In : Journal of Investigative Dermatology. 105, 4, p. 592-596 5 p.

Research output: Contribution to journalArticle

Open Access
55 Scopus citations

2-Benzazolyl-4-Piperazin-1- Ylsulfonylbenzenecarbohydroxamic acids as novel selective histone deacetylase-6 inhibitors with antiproliferative activity

Wang, L., Kofler, M., Brosch, G., Melesina, J., Sippl, W., Martinez, E. D. & Easmon, J., Dec 1 2015, In : PloS one. 10, 12, e0134556.

Research output: Contribution to journalArticle

5 Scopus citations

2-Bromopalmitate Reduces Protein Deacylation by Inhibition of Acyl-Protein Thioesterase Enzymatic Activities

Pedro, M. P., Vilcaes, A. A., Tomatis, V. M., Oliveira, R. G., Gomez, G. A. & Daniotti, J. L., Oct 2 2013, In : PloS one. 8, 10, e75232.

Research output: Contribution to journalArticle

26 Scopus citations

2-Chloropyridazin-3(2H)-ones as electrophilic chlorinating agents: Effective α-chlorination of active methylene/methine compounds

Park, Y. D., Kim, J. J., Cho, S. D., Lee, S. G., Falck, J. R. & Yoon, Y. J., May 2 2005, In : Synthesis. 7, p. 1136-1140 5 p.

Research output: Contribution to journalArticle

22 Scopus citations

2-Cyanopyridazin-3(2H)-ones: Effective and chemoselective electrophilic cyanating agents

Kim, J. J., Kweon, D. H., Cho, S. D., Kim, H. K., Jung, E. Y., Lee, S. G., Falck, J. R. & Yoon, Y. J., Jun 13 2005, In : Tetrahedron. 61, 24, p. 5889-5894 6 p.

Research output: Contribution to journalArticle

40 Scopus citations

2-Deoxy derivative is a partial agonist of the intracellular messenger inositol 3,4,5,6-tetrakisphosphate in the epithelial cell line T84

Rudolf, M. T., Li, W. H., Wolfson, N., Traynor-Kaplan, A. E. & Schultz, C., Sep 10 1998, In : Journal of Medicinal Chemistry. 41, 19, p. 3635-3644 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

2D gel electrophoresis reveals dynamics of t-loop formation during the cell cycle and t-loop in maintenance regulated by heterochromatin state

Zhang, Z., Zhang, T., Ge, Y., Tang, M., Ma, W., Zhang, Q., Gong, S., Wright, W. E., Shay, J., Liu, H. & Zhao, Y., Apr 19 2019, In : Journal of Biological Chemistry. 294, 16, p. 6645-6656 12 p.

Research output: Contribution to journalArticle

2D phase contrast blood flow velocity measurements of the thoracic vasculature: comparison of the effect of gadofosveset trisodium and gadopentetate dimeglumine

Makowski, M. R., Wiethoff, A. J., Ebersberger, H. U., Botnar, R. M., Razavi, R., Schaeffter, T. & Greil, G. F., Feb 27 2015, In : International Journal of Cardiovascular Imaging. 31, 2, p. 409-416 8 p.

Research output: Contribution to journalArticle

3 Scopus citations
444 Scopus citations

2-hydroxyglutarate inhibits ATP synthase and mTOR Signaling

Fu, X., Chin, R. M., Vergnes, L., Hwang, H., Deng, G., Xing, Y., Pai, M. Y., Li, S., Ta, L., Fazlollahi, F., Chen, C., Prins, R. M., Teitell, M. A., Nathanson, D. A., Lai, A., Faull, K. F., Jiang, M., Clarke, S. G., Cloughesy, T. F., Graeber, T. G. & 5 others, Braas, D., Christofk, H. R., Jung, M. E., Reue, K. & Huang, J., Sep 1 2015, In : Cell Metabolism. 22, 3, p. 508-515 8 p.

Research output: Contribution to journalArticle

82 Scopus citations

2-methoxyestradiol prevents LNCaP tumor development in nude mice: Potential role of G2/M regulatory proteins

Horny, C., Sri Balasubashini, M., Komanduri, K., Ganapathy, M., Yeh, I. T., Ghosh, R. & Kumar, A. P., Jan 1 2009, In : Journal of Cell Death. 2009, p. 1-8 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

2-NBDG fluorescence imaging of hypermetabolic circulating tumor cells in mouse xenograft model of breast cancer

Cai, H. & Peng, F., Jan 1 2013, In : Journal of Fluorescence. 23, 1, p. 213-220 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

2-Pyrrolidinone and succinimide as clinical screening biomarkers for gaba-transaminase deficiency: Anti-seizure medications impact accurate diagnosis

Kennedy, A. D., Pappan, K. L., Donti, T., Delgado, M. R., Shinawi, M., Pearson, T. S., Lalani, S. R., Craigen, W. E., Sutton, V. R., Evans, A. M., Sun, Q., Emrick, L. T. & Elsea, S. H., 2019, In : Frontiers in Neuroscience. 13, MAY, 394.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

2-Tier in-plane motion correction and out-of-plane motion filtering for contrast-enhanced ultrasound

Ta, C. N., Eghtedari, M., Mattrey, R. F., Kono, Y. & Kummel, A. C., Nov 1 2014, In : Investigative Radiology. 49, 11, p. 707-719 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

2-Year Outcomes After Stenting of Lipid-Rich and Nonrich Coronary Plaques

Yamamoto, M. H., Maehara, A., Stone, G. W., Kini, A. S., Brilakis, E. S., Rizik, D. G., Shunk, K., Powers, E. R., Tobis, J. M., Maini, B. S., Dixon, S. R., Goldstein, J. A., Petersen, J. L., Généreux, P., Shah, P. R., Crowley, A., Nicholls, S. J., Mintz, G. S., Muller, J. E. & Weisz, G., Mar 31 2020, In : Journal of the American College of Cardiology. 75, 12, p. 1371-1382 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

2′-5′-Oligoadenylate synthetase is activated by a specific RNA sequence motif

Kodym, R., Kodym, E. & Story, M. D., Oct 16 2009, In : Biochemical and Biophysical Research Communications. 388, 2, p. 317-322 6 p.

Research output: Contribution to journalArticle

30 Scopus citations

2′-Hydroxyflavanone inhibits prostate tumor growth through inactivation of AKT/STAT3 signaling and induction of cell apoptosis

Wu, K., Ning, Z., Zhou, J., Wang, B., Fan, J., Zhu, J., Gao, Y., Wang, X., Hsieh, J. T. & He, D., Jul 2014, In : Oncology reports. 32, 1, p. 131-138 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

3,4-Didehydropyridine plus cyclopentadiene: [2+2] or [4+2]-cycloaddition ?

Reinecke, M. G., Sherwood Brown, E., Capehart, B. P., Minter, D. E. & Freeman, R. K., 1988, In : Tetrahedron. 44, 18, p. 5675-5680 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

3,4-Epoxy-1-butene, a reactive metabolite of 1,3-butadiene, induces somatic mutations in Xpc-null mice

Wickliffe, J. K., Galbert, L. A., Ammenheuser, M. M., Herring, S. M., Xie, J., Masters, O. E., Friedberg, E. C., Lloyd, R. S. & Ward, J. B., Jan 1 2006, In : Environmental and Molecular Mutagenesis. 47, 1, p. 67-70 4 p.

Research output: Contribution to journalArticle

8 Scopus citations
34 Scopus citations

3.5 cm artificial urinary sphincter cuff erosion occurs predominantly in irradiated patients

Simhan, J., Morey, A., Singla, N., Tausch, T. J., Scott, J. F., Lemack, G. E. & Roehrborn, C., Feb 1 2015, In : Journal of Urology. 193, 2, p. 593-597 5 p.

Research output: Contribution to journalArticle

47 Scopus citations

3(S)-hydroxy-leukotriene B4 is a potent granulocyte chemotaxin in the guinea pig dermis

Fretland, D., Anglin, C., Baron, D., Widomski, D., Chauhan, K., Bhatt, R. & Falck, J., Aug 1 1995, In : Inflammation Research. 44, 2 Supplement, p. S137-S138

Research output: Contribution to journalArticle

303 Aneurysmal Subarachnoid Hemorrhage Patients' Risk Assessment for Shunting (aSAH-PARAS): An International Collaborative Study and Initiation of a Consortium

Adams, H., Ban, V. S., Leinonen, V., Aoun, S. G., Huttunen, J., Saavalainen, T., Lindgren, A., Frosen, J., Fraunberg, M., Koivisto, T. S., Hernesniemi, J. A., Welch, B. G. & Jaaskelaine, J., Aug 1 2016, In : Neurosurgery. 63, p. 186-187 2 p.

Research output: Contribution to journalArticle

2 Scopus citations

30-Day Readmission after Spine Surgery

Adogwa, O., Elsamadicy, A. A., Han, J. L., Karikari, I. O., Cheng, J. & Bagley, C. A., Apr 1 2017, In : Spine. 42, 7, p. 520-524 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

315 Race as a Predictor of Postoperative Hospital Readmission After Spine Surgery

Martin, J., Wang, T. Y., Loriaux, D. B., Desai, R., Adogwa, O., Kuchibhatla, M., Karikari, I. O., Bagley, C. A. & Gottfried, O. N., Aug 1 2016, In : Neurosurgery. 63, 1 p.

Research output: Contribution to journalArticle

5 Scopus citations

31P and 1H MRS of DB-1 melanoma xenografts: Lonidamine selectively decreases tumor intracellular pH and energy status and sensitizes tumors to melphalan

Nath, K., Nelson, D. S., Ho, A. M., Lee, S. C., Darpolor, M. M., Pickup, S., Zhou, R., Heitjan, D. F., Leeper, D. B. & Glickson, J. D., Jan 2013, In : NMR in biomedicine. 26, 1, p. 98-105 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

31P and 23Na NMR lanthanide induced shifts in axially symmetric macrocyclic phosphonate complexes

Dean Sherry, A., Geraldes, C. F. G. C. & Cacheris, W. P., Dec 1 1987, In : Inorganica Chimica Acta. 139, 1-2, p. 137-139 3 p.

Research output: Contribution to journalArticle

38 Scopus citations

31P localized magnetic resonance spectroscopy of head and neck tumors - preliminary findings

Hendrix, R. A., Lenkinski, R. E., Vogele, K., Bloch, P. & McKenna, W. G., Jan 1 1990, In : Otolaryngology - Head and Neck Surgery. 103, 5 I, p. 775-783 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

31P magnetic resonance spectroscopy to measure in vivo cardiac energetics in normal myocardium and hypertrophic cardiomyopathy: Experiences at 3 T

Shivu, G. N., Abozguia, K., Phan, T. T., Ahmed, I., Henning, A. & Frenneaux, M., Feb 1 2010, In : European Journal of Radiology. 73, 2, p. 255-259 5 p.

Research output: Contribution to journalArticle

33 Scopus citations
36 Scopus citations

31P NMR spectroscopy of perinatal hypoxic‐ischemic brain damage: A model to evaluate neuroprotective drugs in immature rats

William, G. D., Palmer, C., Roberts, R. L., Heitjan, D. F. & Smith, M. B., Jan 1 1992, In : NMR in biomedicine. 5, 3, p. 145-153 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

335'Base deletion in the mRNA coding for a dibasic aniino acid transporteivlike protein (SLC3A1) isolated from a patient with cystinuria

Gitomer, W. L., Reed, B. Y., Ruml, L. A. & Pack, C. Y. C., 1998, In : Human mutation. 11, SUPPL 1, p. S69-S71

Research output: Contribution to journalArticle

12 Scopus citations

337 Expansion of Dendritic Cells Using FLT3 Ligand to Treat Glioblastoma: A Preclinical Study

Garzon-Muvdi, T., Mangraviti, A., Theodros, D., Kim, E., Yellin, M. J., Marsh, H. & Lim, M., Aug 1 2016, In : Neurosurgery. 63, p. 198-199 2 p.

Research output: Contribution to journalArticle

3-52 A Comparison of Letrozole and Tamoxifen in Postmenopausal Women With Early Breast Cancer

Haley, B. B., Oct 1 2006, In : Breast Diseases. 17, 3, p. 284-285 2 p.

Research output: Contribution to journalArticle

39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/α2-macroglobulin receptor

Herz, J., Goldstein, J. L., Strickland, D. K., Ho, Y. K. & Brown, M. S., Jan 1 1991, In : Journal of Biological Chemistry. 266, 31, p. 21232-21238 7 p.

Research output: Contribution to journalArticle

452 Scopus citations
12 Scopus citations

39K NMR measurement of intracellular potassium during ischemia in the perfused guinea pig heart

Radford, N. B., Babcock, E. E., Richman, A., Szczepaniak, L., Malloy, C. R. & Sherry, A. D., Oct 1 1998, In : Magnetic resonance in medicine. 40, 4, p. 544-550 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

3-alpha-androstanediol and prostatic growth: Comparison of 3-alpha-androstanediol formation in prostates from 8 species including man and dog

Jacobi, G. H. & Wilson, J. D., Jan 1 1979, In : Journal of Urology. 121, 5, p. 612-614 3 p.

Research output: Contribution to journalArticle

4 Scopus citations

3Conserved cryptic recombination signals in Vκ gene segments are cleaved in small pre-B cells

Lieberman, A. E., Kuraoka, M., Davila, M., Kelsoe, G. & Cowell, L. G., Jun 25 2009, In : BMC Immunology. 10, 37.

Research output: Contribution to journalArticle

3 Scopus citations

3D-2D Deformable Image Registration Using Feature-Based Nonuniform Meshes

Zhong, Z., Guo, X., Cai, Y., Yang, Y., Wang, J., Jia, X. & Mao, W., 2016, In : BioMed Research International. 2016, 4382854.

Research output: Contribution to journalArticle

2 Scopus citations

3D advanced imaging overlay with rapid registration in CHD to reduce radiation and assist cardiac catheterisation interventions

Arar, Y., Reddy, S. R. V., Kim, H., Vivian Dimas, V., Zellers, T. M., Abou Zahr, R., Vamsee, R., Greer, J. S., Tandon, A., Pontiki, A., Dillenbeck, J., Zabala, L., Greil, G., Nugent, A. W. & Hussain, T., May 1 2020, In : Cardiology in the Young. 30, 5, p. 656-662 7 p.

Research output: Contribution to journalArticle

3D conformal MRI-controlled transurethral ultrasound prostate therapy: Validation of numerical simulations and demonstration in tissue-mimicking gel phantoms

Burtnyk, M., N'Djin, W. A., Kobelevskiy, I., Bronskill, M. & Chopra, R., Nov 21 2010, In : Physics in medicine and biology. 55, 22, p. 6817-6839 23 p.

Research output: Contribution to journalArticle

15 Scopus citations

3D CT-based volumetric dose assessment of 2D plans using GEC-ESTRO guidelines for cervical cancer brachytherapy

Gao, M., Albuquerque, K., Chi, A. & Rusu, I., Jan 1 2010, In : Brachytherapy. 9, 1, p. 55-60 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

3D CT segmentation of CAM type femoroacetabular impingement-reliability and relationship of CAM lesion with anthropomorphic features

Zhang, L., Wells, J., Dessouky, R., Gleason, A., Chopra, R., Inoff, Y. C., Fey, N., Xi, Y. & Chhabra, A., 2018, In : British Journal of Radiology. 91, 1092

Research output: Contribution to journalArticle

1 Scopus citations

3D Culture Supports Long-Term Expansion of Mouse and Human Nephrogenic Progenitors

Li, Z., Araoka, T., Wu, J., Liao, H. K., Li, M., Lazo, M., Zhou, B., Sui, Y., Wu, M. Z., Tamura, I., Xia, Y., Beyret, E., Matsusaka, T., Pastan, I., Rodriguez Esteban, C., Guillen, I., Guillen, P., Campistol, J. M. & Izpisua Belmonte, J. C., Oct 6 2016, In : Cell Stem Cell. 19, 4, p. 516-529 14 p.

Research output: Contribution to journalArticle

Open Access
70 Scopus citations

3'-deoxy-3'-[ 18 F]fluorothymidine PET quantification of bone marrow response to radiation dose

McGuire, S. M., Menda, Y., Boles Ponto, L. L., Gross, B., Buatti, J. & Bayouth, J. E., Nov 1 2011, In : International Journal of Radiation Oncology Biology Physics. 81, 3, p. 888-893 6 p.

Research output: Contribution to journalArticle

24 Scopus citations