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  • William M Lee
2020

Acute liver failure – Authors' reply

Stravitz, R. T. & Lee, W. M., Jun 13 2020, In : The Lancet. 395, 10240, p. 1833-1834 2 p.

Research output: Contribution to journalLetter

Open Access

Admission Factor V Predicts Transplant-Free Survival in Acute Liver Failure

Patidar, K. R., Davis, B. C., Slaven, J. E., Ghabril, M. S., Kubal, C. A., Lee, W. M. & Stravitz, R. T., Jan 1 2020, (Accepted/In press) In : Digestive Diseases and Sciences.

Research output: Contribution to journalArticle

Advances in biomarker development in acetaminophen toxicity

James, L. P., McGill, M. R., Roberts, D. W., Hinson, J. A. & Lee, W. M., 2020, (Accepted/In press) Advances in Clinical Chemistry. Academic Press Inc., (Advances in Clinical Chemistry).

Research output: Chapter in Book/Report/Conference proceedingChapter

Alcohol consumption is associated with the severity and outcome of acute liver injury/failure

the Acute Liver Failure Study Group, Feb 1 2020, In : Liver International. 40, 2, p. 360-367 8 p.

Research output: Contribution to journalArticle

Elevated Serum Liver-Type Fatty Acid Binding Protein Levels in Non-acetaminophen Acute Liver Failure Patients with Organ Dysfunction

For the US Acute Liver Failure Study Group, Jan 1 2020, (Accepted/In press) In : Digestive Diseases and Sciences.

Research output: Contribution to journalArticle

1 Scopus citations

In-depth serum virome analysis in patients with acute liver failure with indeterminate etiology

Ren, Y., Xu, Y., Lee, W. M., Di Bisceglie, A. M. & Fan, X., Jan 1 2020, In : Archives of Virology. 165, 1, p. 127-135 9 p.

Research output: Contribution to journalArticle

Liver Transplantation for Acetaminophen-Induced Acute Liver Failure: Role of Psychiatric Comorbidity in Listing Decisions and Outcomes

for the Acute Liver Failure Study Group, Jun 1 2020, In : Digestive Diseases and Sciences. 65, 6, p. 1861-1868 8 p.

Research output: Contribution to journalArticle

Outcomes of Acute Liver Injury in Adults Due to Wilson’s Disease: Is Survival Without Transplant Possible?

Camarata, M. A., Gottfried, M., Rule, J. A., Ala, A., Lee, W. M., Todd Stravitz, R. & Schilsky, M. L., Mar 1 2020, In : Liver Transplantation. 26, 3, p. 330-336 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Prevalence and clinical features of patients with concurrent HBsAg and anti-HBs: Evaluation of the hepatitis B research network cohort

Lee, W. M., King, W. C., Schwarz, K. B., Rule, J. & Lok, A. S. F., 2020, (Accepted/In press) In : Journal of Viral Hepatitis.

Research output: Contribution to journalArticle

Open Access

Reply

Leventhal, T. M. & Lee, W. M., Apr 2020, In : Clinical Gastroenterology and Hepatology. 18, 4, 1 p.

Research output: Contribution to journalLetter

Significant lung injury and its prognostic significance in acute liver failure: A cohort analysis

Dong, V., Sun, K., Gottfried, M., Cardoso, F. S., McPhail, M. J., Stravitz, R. T., Lee, W. M. & Karvellas, C. J., Mar 1 2020, In : Liver International. 40, 3, p. 654-663 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

The macrophage activation marker soluble CD163 is elevated and associated with liver disease phenotype in patients with Wilson's disease

Glavind, E., Gotthardt, D. N., Pfeiffenberger, J., Sandahl, T. D., Bashlekova, T., Willemoe, G. L., Hasselby, J. P., Weiss, K. H., Møller, H. J., Vilstrup, H., Lee, W. M., Schilsky, M. L., Ott, P. & Grønbæk, H., Jul 2 2020, In : Orphanet Journal of Rare Diseases. 15, 1, 173.

Research output: Contribution to journalArticle

Open Access

Transaldolase haploinsufficiency in subjects with acetaminophen-induced liver failure

Oaks, Z., Jimah, J., Grossman, C. C., Beckford, M., Kelly, R., Banerjee, S., Niland, B., Miklossy, G., Kuloglu, Z., Kansu, A., Lee, W., Szonyi, L., Banki, K. & Perl, A., May 1 2020, In : Journal of Inherited Metabolic Disease. 43, 3, p. 496-506 11 p.

Research output: Contribution to journalArticle

Open Access

Variability and Lability of Ammonia Levels in Healthy Volunteers and Patients With Cirrhosis: Implications for Trial Design and Clinical Practice

Bajaj, J. S., Bloom, P. P., Chung, R. T., Hassanein, T. I., Padilla-Martinez, M., Kayali, Z., Rockey, D. C., Sasso, R., Muthukumar, A. R., Lee, W. M., Denney, W. S., Gavis, E. A., Anderson, C., Blankstein, L., Brennan, A. M., Puurunen, M. K. & Lawitz, E., May 1 2020, In : The American Journal of Gastroenterology. 115, 5, p. 783-785 3 p.

Research output: Contribution to journalArticle

Open Access
2019

Acetaminophen is Undetectable in Plasma From More Than Half of Patients Believed to Have Acute Liver Failure Due to Overdose

Acute Liver Failure Study Group, Sep 1 2019, In : Clinical Gastroenterology and Hepatology. 17, 10, p. 2110-2116 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Acute liver failure

Stravitz, R. T. & Lee, W. M., Sep 7 2019, In : The Lancet. 394, 10201, p. 869-881 13 p.

Research output: Contribution to journalReview article

25 Scopus citations

Age, race and viral genotype are associated with the prevalence of hepatitis B e antigen in children and adults with chronic hepatitis B

the Hepatitis B Research Network (HBRN), Jul 2019, In : Journal of Viral Hepatitis. 26, 7, p. 856-865 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Changes in alpha-foetoprotein and Gc-globulin in relation to outcomes in non-acetaminophen acute liver failure

Singh, S., Hynan, L. S., Rule, J. A. & Lee, W. M., Jan 1 2019, (Accepted/In press) In : Liver International.

Research output: Contribution to journalArticle

Correction: Cytokine profiles in acute liver injury-Results from the US Drug-Induced Liver Injury Network (DILIN) and the Acute Liver Failure Study Group (PLoS ONE (2018) 13:10 (e0206389) DOI: 10.1371/journal.pone.0206389)

US Drug-Induced Liver Injury Network and the Acute Liver Failure Study Group, Feb 2019, In : PloS one. 14, 2, e0212394.

Research output: Contribution to journalComment/debate

Open Access

Distinct phenotype and function of circulating Vδ1+ and Vδ2+ γδT-cells in acute and chronic hepatitis B

Chang, K. M., Traum, D., Park, J. J., Ho, S., Ojiro, K., Wong, D. K., Wahed, A. S., Terrault, N. A., Khalili, M., Sterling, R. K., Janssen, H. L. A., Shuhart, M. C., Lau, D. T., Roberts, L. R., Johnson, G. S., Kaplan, D. E., Betts, M. R., Lee, W. M. & Lok, A. S. F., 2019, In : PLoS pathogens. 15, 4, e1007715.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
Open Access

Herpes Simplex Virus–Associated Acute Liver Failure Often Goes Unrecognized

the Acute Liver Failure Study Group, Jan 1 2019, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

4 Scopus citations

Host Genetic Variant in CXCL16 May Be Associated With Hepatitis B Virus–Related Acute Liver Failure

Ajmera, V., Huang, H., Dao, D., Feld, J. J., Lau, D. T., Patel, K., Rule, J. A., Daly, M., Lee, W. M. & Chung, R. T., Jan 1 2019, (Accepted/In press) In : CMGH.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Leukocyte cell derived chemotaxin-2 (Lect2) as a predictor of survival in adult acute liver failure

Slowik, V., Borude, P., Jaeschke, H., Woolbright, B. L., Lee, W. M. & Apte, U., Mar 1 2019, In : Translational Gastroenterology and Hepatology. 4, March, 17.

Research output: Contribution to journalArticle

1 Scopus citations

Low Serum Hepcidin Is Associated With Reduced Short-Term Survival in Adults With Acute Liver Failure

for the Acute Liver Failure Study Group (ALFSG), May 2019, In : Hepatology. 69, 5, p. 2136-2149 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

Phase Transition Is Infrequent Among North American Adults With e-Antigen-Negative Chronic Hepatitis B and Low-Level Viremia

Zhou, K., Wahed, A. S., Cooper, S., Di Bisceglie, A. M., Fontana, R. J., Ghany, M. G., Khalili, M., Lok, A. S., Perrillo, R., Lee, W. M., Lau, D. T. Y., Sterling, R., Janssen, H. L. A. & Terrault, N. A., Nov 1 2019, In : The American Journal of Gastroenterology. 114, 11, p. 1753-1763 11 p.

Research output: Contribution to journalArticle

The Revolution in Treatment of Hepatitis C

Mayberry, J. & Lee, W. M., Jan 1 2019, In : Medical Clinics of North America. 103, 1, p. 43-55 13 p.

Research output: Contribution to journalReview article

3 Scopus citations

Whole Exome Sequencing Among 26 Patients With Indeterminate Acute Liver Failure: A Pilot Study

Acute Liver Failure Study Group, Oct 1 2019, In : Clinical and translational gastroenterology. 10, 10, p. e00087

Research output: Contribution to journalArticle

Open Access
2018

Acetaminophen-induced Acute Liver Failure Is More Common and More Severe in Women

Acute Liver Failure Study Group, Jan 1 2018, (Accepted/In press) In : Clinical Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

9 Scopus citations

Acute Liver Failure from Tumor Necrosis Factor-α Antagonists: Report of Four Cases and Literature Review

for the United States Acute Liver Failure Study Group, Jun 1 2018, In : Digestive Diseases and Sciences. 63, 6, p. 1654-1666 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Acute liver failure induced by idiosyncratic reaction to drugs: Challenges in diagnosis and therapy

Tujios, S. R. & Lee, W. M., Jan 1 2018, In : Liver International. 38, 1, p. 6-14 9 p.

Research output: Contribution to journalReview article

22 Scopus citations

Acute Liver Failure of Indeterminate Etiology: A Comprehensive Systematic Approach by An Expert Committee to Establish Causality

for the Acute Liver Failure Study Group, Sep 1 2018, In : American Journal of Gastroenterology. 113, 9, p. 1319-1328 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

Bleeding complications in acute liver failure

Stravitz, R. T., Ellerbe, C., Durkalski, V., Schilsky, M., Fontana, R. J., Peterseim, C. & Lee, W. M., May 2018, In : Hepatology. 67, 5, p. 1931-1942 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

Comment on: MARS system effectively replaces hepatic function in severe acute liver failure

US Acute Liver Failure Study Group, Jan 1 2018, In : Annals of surgery. 268, 6, p. e63-e64

Research output: Contribution to journalLetter

Cytokine profiles in acute liver injury—Results from the US Drug-Induced Liver Injury Network (DILIN) and the Acute Liver Failure Study Group

Bonkovsky, H. L., Barnhart, H. X., Foureau, D. M., Steuerwald, N., Lee, W. M., Gu, J., Fontana, R. J., Hayashi, P. J., Chalasani, N., Navarro, V. M., Odin, J., Stolz, A., Watkins, P. B. & Serrano, J., Oct 2018, In : PloS one. 13, 10, e0206389.

Research output: Contribution to journalArticle

8 Scopus citations

Multiple admissions for acetaminophen overdose: Acetaminophen frequent fliers, a new entity?

Yang, E., Peng, L. & Lee, W. M., Jan 1 2018, (Accepted/In press) In : Hepatology.

Research output: Contribution to journalArticle

1 Scopus citations

Safety, tolerability, and pharmacokinetics of l-ornithine phenylacetate in patients with acute liver injury/failure and hyperammonemia

Stravitz, R. T., Gottfried, M., Durkalski, V., Fontana, R. J., Hanje, A. J., Koch, D., Hameed, B., Ganger, D., Subramanian, R. M., Bukofzer, S., Ravis, W. R., Clasen, K., Sherker, A., Little, L. & Lee, W. M., Mar 2018, In : Hepatology. 67, 3, p. 1003-1013 11 p.

Research output: Contribution to journalArticle

8 Scopus citations
2017

Acetaminophen (APAP) hepatotoxicity-Isn't it time for APAP to go away?

Lee, W. M., 2017, (Accepted/In press) In : Journal of Hepatology.

Research output: Contribution to journalArticle

62 Scopus citations

Association of Variants of Arginine Vasopressin and Arginine Vasopressin Receptor 1A With Severe Acetaminophen Liver Injury

Randesi, M., Levran, O., Correa da Rosa, J., Hankins, J., Rule, J., Kreek, M. J., Lee, W. M., Reuben, A., Fontana, R. J., Davern, T., McGuire, B., Stravitz, R. T., Durkalski, V., Liou, I., Fix, O., Schilsky, M., Ganger, D., Chung, R. T., Koch, D., Reddy, K. R. & 1 others, Rossaro, L., May 1 2017, In : CMGH. 3, 3, p. 500-505 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Budd-chiari syndrome causing acute liver failure: A multicenter case series

the Acute Liver Failure Study Group, Feb 1 2017, In : Liver Transplantation. 23, 2, p. 135-142 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Determination of hepatitis B phenotype using biochemical and serological markers

the Hepatitis B Research Network (HBRN), Apr 1 2017, In : Journal of Viral Hepatitis. 24, 4, p. 320-329 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Elbasvir/Grazoprevir for Patients With Hepatitis C Virus Infection and Inherited Blood Disorders: A Phase III Study

on behalf of the C-EDGE IBLD Study Investigators, Sep 1 2017, In : Hepatology. 66, 3, p. 736-745 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

Elevated FABP1 serum levels are associated with poorer survival in acetaminophen-induced acute liver failure

For the US Acute Liver Failure Study Group, Mar 1 2017, In : Hepatology. 65, 3, p. 938-949 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

HBV-Associated Acute Liver Failure After Immunosuppression and Risk of Death

Karvellas, C. J., Cardoso, F. S., Gottfried, M., Reddy, K. R., Hanje, A. J., Ganger, D. & Lee, W. M., Jan 1 2017, In : Clinical Gastroenterology and Hepatology. 15, 1, p. 113-122 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Heat stroke leading to acute liver injury & failure: A case series from the Acute Liver Failure Study Group

Davis, B. C., Tillman, H., Chung, R. T., Stravitz, R. T., Reddy, R., Fontana, R. J., Mcguire, B., Davern, T. & Lee, W. M., 2017, (Accepted/In press) In : Liver International.

Research output: Contribution to journalArticle

19 Scopus citations

miRNA-122 Protects Mice and Human Hepatocytes from Acetaminophen Toxicity by Regulating Cytochrome P450 Family 1 Subfamily A Member 2 and Family 2 Subfamily E Member 1 Expression

Chowdhary, V., Teng, K. Y., Thakral, S., Zhang, B., Lin, C. H., Wani, N., Bruschweiler-Li, L., Zhang, X., James, L., Yang, D., Junge, N., Brüschweiler, R., Lee, W. M. & Ghoshal, K., Dec 2017, In : American Journal of Pathology. 187, 12, p. 2758-2774 17 p.

Research output: Contribution to journalArticle

11 Scopus citations

Prevalence of hepatitis B antiviral drug resistance variants in North American patients with chronic hepatitis B not receiving antiviral treatment

Lok, A. S., Ganova-Raeva, L., Cloonan, Y., Punkova, L., Lin, H. H. S., Lee, W. M. & Ghany, M. G., Nov 2017, In : Journal of Viral Hepatitis. 24, 11, p. 1032-1042 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Psychosocial and behavioral factors in acetaminophen-related acute liver failure and liver injury

Pezzia, C., Sanders, C., Welch, S., Bowling, A. & Lee, W. M., Oct 2017, In : Journal of Psychosomatic Research. 101, p. 51-57 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Reply

On behalf of the ALFSG, Jan 1 2017, In : Hepatology. 65, 1, p. 389-390 2 p.

Research output: Contribution to journalLetter