A brain magnetic resonance imaging study of pituitary gland morphology in anorexia nervosa and bulimia

P. Murali Doraiswamy, K. Ranga Rama Krishnan, Gary S. Figiel, Mustafa M. Husain, Orest B. Boyko, W. J. Kenneth Rockwell, Everett H. Ellinwood

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Magnetic resonance imaging (MRI) of the brain was used to examine the morphology and dimensions of the pituitary gland in 18 patients with eating disorders (8 anorectics and 10 bulimics), in comparison with 13 healthy volunteers. None of the 18 patients with anorexia or bulimia had any radiological evidence suggestive of pituitary macroadenoma. cyst, or empty sella. Measurements revealed that the anorectics and bulimics had smaller pituitary gland cross-sectional areas (p < 0.05) and smaller pituitary gland heights, compared with healthy controls. These preliminary findings in anorectics and bulimics are suggestive of pituitary atrophy secondary to nutritional or endocrine alterations, rather than a primary pituitary pathology.

Original languageEnglish (US)
Pages (from-to)110-116
Number of pages7
JournalBiological Psychiatry
Volume28
Issue number2
DOIs
StatePublished - Jul 15 1990

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Appetite Depressants
Bulimia
Anorexia Nervosa
Pituitary Gland
Magnetic Resonance Imaging
Brain
Anorexia
Atrophy
Cysts
Healthy Volunteers
Pathology

ASJC Scopus subject areas

  • Biological Psychiatry

Cite this

Murali Doraiswamy, P., Ranga Rama Krishnan, K., Figiel, G. S., Husain, M. M., Boyko, O. B., Kenneth Rockwell, W. J., & Ellinwood, E. H. (1990). A brain magnetic resonance imaging study of pituitary gland morphology in anorexia nervosa and bulimia. Biological Psychiatry, 28(2), 110-116. https://doi.org/10.1016/0006-3223(90)90628-F

A brain magnetic resonance imaging study of pituitary gland morphology in anorexia nervosa and bulimia. / Murali Doraiswamy, P.; Ranga Rama Krishnan, K.; Figiel, Gary S.; Husain, Mustafa M.; Boyko, Orest B.; Kenneth Rockwell, W. J.; Ellinwood, Everett H.

In: Biological Psychiatry, Vol. 28, No. 2, 15.07.1990, p. 110-116.

Research output: Contribution to journalArticle

Murali Doraiswamy, P, Ranga Rama Krishnan, K, Figiel, GS, Husain, MM, Boyko, OB, Kenneth Rockwell, WJ & Ellinwood, EH 1990, 'A brain magnetic resonance imaging study of pituitary gland morphology in anorexia nervosa and bulimia', Biological Psychiatry, vol. 28, no. 2, pp. 110-116. https://doi.org/10.1016/0006-3223(90)90628-F
Murali Doraiswamy P, Ranga Rama Krishnan K, Figiel GS, Husain MM, Boyko OB, Kenneth Rockwell WJ et al. A brain magnetic resonance imaging study of pituitary gland morphology in anorexia nervosa and bulimia. Biological Psychiatry. 1990 Jul 15;28(2):110-116. https://doi.org/10.1016/0006-3223(90)90628-F
Murali Doraiswamy, P. ; Ranga Rama Krishnan, K. ; Figiel, Gary S. ; Husain, Mustafa M. ; Boyko, Orest B. ; Kenneth Rockwell, W. J. ; Ellinwood, Everett H. / A brain magnetic resonance imaging study of pituitary gland morphology in anorexia nervosa and bulimia. In: Biological Psychiatry. 1990 ; Vol. 28, No. 2. pp. 110-116.
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