TY - JOUR
T1 - A brain magnetic resonance imaging study of pituitary gland morphology in anorexia nervosa and bulimia
AU - Murali Doraiswamy, P.
AU - Ranga Rama Krishnan, K.
AU - Figiel, Gary S.
AU - Husain, Mustafa M.
AU - Boyko, Orest B.
AU - Kenneth Rockwell, W. J.
AU - Ellinwood, Everett H.
N1 - Funding Information:
This work was supported in part by NIMH-MH 42210. We are indebted to Mr. Robert A. Bums mid all the MRI staff for their expert technical assistance. We are grateful to Lou T. Mallard, RN for helping with the
PY - 1990/7/15
Y1 - 1990/7/15
N2 - Magnetic resonance imaging (MRI) of the brain was used to examine the morphology and dimensions of the pituitary gland in 18 patients with eating disorders (8 anorectics and 10 bulimics), in comparison with 13 healthy volunteers. None of the 18 patients with anorexia or bulimia had any radiological evidence suggestive of pituitary macroadenoma. cyst, or empty sella. Measurements revealed that the anorectics and bulimics had smaller pituitary gland cross-sectional areas (p < 0.05) and smaller pituitary gland heights, compared with healthy controls. These preliminary findings in anorectics and bulimics are suggestive of pituitary atrophy secondary to nutritional or endocrine alterations, rather than a primary pituitary pathology.
AB - Magnetic resonance imaging (MRI) of the brain was used to examine the morphology and dimensions of the pituitary gland in 18 patients with eating disorders (8 anorectics and 10 bulimics), in comparison with 13 healthy volunteers. None of the 18 patients with anorexia or bulimia had any radiological evidence suggestive of pituitary macroadenoma. cyst, or empty sella. Measurements revealed that the anorectics and bulimics had smaller pituitary gland cross-sectional areas (p < 0.05) and smaller pituitary gland heights, compared with healthy controls. These preliminary findings in anorectics and bulimics are suggestive of pituitary atrophy secondary to nutritional or endocrine alterations, rather than a primary pituitary pathology.
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U2 - 10.1016/0006-3223(90)90628-F
DO - 10.1016/0006-3223(90)90628-F
M3 - Article
C2 - 2378917
AN - SCOPUS:0025279605
SN - 0006-3223
VL - 28
SP - 110
EP - 116
JO - Biological Psychiatry
JF - Biological Psychiatry
IS - 2
ER -