A Case Report of Breakthrough Infections With 2 SARS-CoV-2 Variants in a Lung Transplant Patient

Research output: Contribution to journalArticlepeer-review

Abstract

A lung transplant (LT) patient developed 2 distinct episodes of COVID-19, confirmed by whole-genome sequencing, which was caused by the Delta, and then followed 6 weeks later, by the Omicron variant. The clinical course with Omicron was more severe, leading us to speculate that Omicron may not be any milder among LT patients. We discuss the potential mechanisms behind the Omicron not being any milder among LT patients and emphasize the need for outcomes data among these patients. Until such data become available, it may be prudent to maintain clinical equipoise as regards the relative virulence of the newer variants among LT patients.

Original languageEnglish (US)
JournalTransplantation proceedings
DOIs
StateAccepted/In press - 2022

ASJC Scopus subject areas

  • Surgery
  • Transplantation

Fingerprint

Dive into the research topics of 'A Case Report of Breakthrough Infections With 2 SARS-CoV-2 Variants in a Lung Transplant Patient'. Together they form a unique fingerprint.

Cite this