A comparison of functional MR activation patterns during silent and audible language tasks

F. Z. Yetkin, T. A. Hammeke, S. J. Swanson, G. L. Morris, W. M. Mueller, T. L. McAuliffe, V. M. Haughton

Research output: Contribution to journalArticle

134 Citations (Scopus)

Abstract

PURPOSE: To compare word generation tasks performed silently and aloud as paradigms for functional MR. METHODS: Images were obtained at 1.5 T, with echoplanar acquisition in nine subjects performing word generation aloud or silently. Functional images created from the echoplanar images by means of cross-correlation techniques were superimposed on anatomic reference images. The location of activation from the two tasks was tabulated; the number of activated pixels in each region from the two tasks was compared. RESULTS: Both silent and aloud word generation produced activation in the inferior frontal lobes, sensorimotor cortex regions, supplementary motor areas, and anterior cingulate gyri, predominantly in the dominant hemisphere. Significantly more activated pixels and fewer artifacts were detected with silent word generation than with word generation aloud. CONCLUSION: Word generation silently or aloud produce activation in the brain. Greater activation can be detected in the left frontal lobe with silent word generation, although the subject's performance of the task cannot be monitored independently during silent word generation.

Original languageEnglish (US)
Pages (from-to)1087-1092
Number of pages6
JournalAmerican Journal of Neuroradiology
Volume16
Issue number5
StatePublished - 1995

Fingerprint

Frontal Lobe
Language
Gyrus Cinguli
Motor Cortex
Task Performance and Analysis
Artifacts
Brain
Sensorimotor Cortex

Keywords

  • Brain, magnetic resonance
  • Magnetic resonance, functional
  • Speech

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Yetkin, F. Z., Hammeke, T. A., Swanson, S. J., Morris, G. L., Mueller, W. M., McAuliffe, T. L., & Haughton, V. M. (1995). A comparison of functional MR activation patterns during silent and audible language tasks. American Journal of Neuroradiology, 16(5), 1087-1092.

A comparison of functional MR activation patterns during silent and audible language tasks. / Yetkin, F. Z.; Hammeke, T. A.; Swanson, S. J.; Morris, G. L.; Mueller, W. M.; McAuliffe, T. L.; Haughton, V. M.

In: American Journal of Neuroradiology, Vol. 16, No. 5, 1995, p. 1087-1092.

Research output: Contribution to journalArticle

Yetkin, FZ, Hammeke, TA, Swanson, SJ, Morris, GL, Mueller, WM, McAuliffe, TL & Haughton, VM 1995, 'A comparison of functional MR activation patterns during silent and audible language tasks', American Journal of Neuroradiology, vol. 16, no. 5, pp. 1087-1092.
Yetkin FZ, Hammeke TA, Swanson SJ, Morris GL, Mueller WM, McAuliffe TL et al. A comparison of functional MR activation patterns during silent and audible language tasks. American Journal of Neuroradiology. 1995;16(5):1087-1092.
Yetkin, F. Z. ; Hammeke, T. A. ; Swanson, S. J. ; Morris, G. L. ; Mueller, W. M. ; McAuliffe, T. L. ; Haughton, V. M. / A comparison of functional MR activation patterns during silent and audible language tasks. In: American Journal of Neuroradiology. 1995 ; Vol. 16, No. 5. pp. 1087-1092.
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