A comprehensive catalogue of somatic mutations in cancer genomes

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

This Hot Topics contribution considers two recently published papers that demonstrate the utility of advanced DNA sequencing technologies for identifying classes of mutations other than base substitutions. Data are presented from genome analyses of immortalized cell lines derived from a malignant melanoma and a small cell carcinoma of the lung. Among other observations the studies suggest the operation of novel DNA repair mechanisms or modes.

Original languageEnglish (US)
Pages (from-to)468-469
Number of pages2
JournalDNA repair
Volume9
Issue number4
DOIs
StatePublished - Apr 4 2010

Keywords

  • Cancer genomes
  • Somatic mutations

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

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