A comprehensive survey of DNA-binding transcription factor gene expression in human fetal and adult organs

Y. Megan Kong; Raymond J. MacDonald; Xiaofei Wen; Peng Yang; Victor M. Barbera; Galvin H. Swift

doi:10.1016/j.modgep.2006.01.002

A comprehensive survey of DNA-binding transcription factor gene expression in human fetal and adult organs

Y. Megan Kong, Raymond J. MacDonald, Xiaofei Wen, Peng Yang, Victor M. Barbera, Galvin H. Swift

Research output: Contribution to journal › Article

11 Scopus citations

Abstract

A global survey of RNA from 14 fetal and 12 adult human organs by RT-PCR determined the expression patterns of 790 genes encoding DNA-binding transcription factors. The data can be sorted to identify sets of transcription factors with expression relatively restricted to a given organ or to particular organ groups. These data are a resource to help define the spectrum of transcription factor control, contribute to the elucidation of transcription factor cascades responsible for the development and maintenance of each organ, and provide a baseline to study the effects of disease or developmental defects.

Original language	English (US)
Pages (from-to)	678-686
Number of pages	9
Journal	Gene Expression Patterns
Volume	6
Issue number	7
DOIs	https://doi.org/10.1016/j.modgep.2006.01.002
State	Published - Oct 1 2006

Keywords

Expression survey
RT-PCR
Transcription factor

ASJC Scopus subject areas

Molecular Biology
Genetics
Developmental Biology

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Kong, Y. M., MacDonald, R. J., Wen, X., Yang, P., Barbera, V. M., & Swift, G. H. (2006). A comprehensive survey of DNA-binding transcription factor gene expression in human fetal and adult organs. Gene Expression Patterns, 6(7), 678-686. https://doi.org/10.1016/j.modgep.2006.01.002

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