Abstract
A global survey of RNA from 14 fetal and 12 adult human organs by RT-PCR determined the expression patterns of 790 genes encoding DNA-binding transcription factors. The data can be sorted to identify sets of transcription factors with expression relatively restricted to a given organ or to particular organ groups. These data are a resource to help define the spectrum of transcription factor control, contribute to the elucidation of transcription factor cascades responsible for the development and maintenance of each organ, and provide a baseline to study the effects of disease or developmental defects.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 678-686 |
| Number of pages | 9 |
| Journal | Gene Expression Patterns |
| Volume | 6 |
| Issue number | 7 |
| DOIs | |
| State | Published - Oct 2006 |
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Keywords
- Expression survey
- RT-PCR
- Transcription factor
ASJC Scopus subject areas
- Genetics
- Molecular Biology
- Cellular and Molecular Neuroscience
- Developmental Neuroscience
Cite this
A comprehensive survey of DNA-binding transcription factor gene expression in human fetal and adult organs. / Kong, Y. Megan; MacDonald, Raymond J.; Wen, Xiaofei; Yang, Peng; Barbera, Victor M.; Swift, Galvin H.
In: Gene Expression Patterns, Vol. 6, No. 7, 10.2006, p. 678-686.Research output: Contribution to journal › Article
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TY - JOUR
T1 - A comprehensive survey of DNA-binding transcription factor gene expression in human fetal and adult organs
AU - Kong, Y. Megan
AU - MacDonald, Raymond J.
AU - Wen, Xiaofei
AU - Yang, Peng
AU - Barbera, Victor M.
AU - Swift, Galvin H.
PY - 2006/10
Y1 - 2006/10
N2 - A global survey of RNA from 14 fetal and 12 adult human organs by RT-PCR determined the expression patterns of 790 genes encoding DNA-binding transcription factors. The data can be sorted to identify sets of transcription factors with expression relatively restricted to a given organ or to particular organ groups. These data are a resource to help define the spectrum of transcription factor control, contribute to the elucidation of transcription factor cascades responsible for the development and maintenance of each organ, and provide a baseline to study the effects of disease or developmental defects.
AB - A global survey of RNA from 14 fetal and 12 adult human organs by RT-PCR determined the expression patterns of 790 genes encoding DNA-binding transcription factors. The data can be sorted to identify sets of transcription factors with expression relatively restricted to a given organ or to particular organ groups. These data are a resource to help define the spectrum of transcription factor control, contribute to the elucidation of transcription factor cascades responsible for the development and maintenance of each organ, and provide a baseline to study the effects of disease or developmental defects.
KW - Expression survey
KW - RT-PCR
KW - Transcription factor
UR - http://www.scopus.com/inward/record.url?scp=33746297174&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33746297174&partnerID=8YFLogxK
U2 - 10.1016/j.modgep.2006.01.002
DO - 10.1016/j.modgep.2006.01.002
M3 - Article
C2 - 16487753
AN - SCOPUS:33746297174
VL - 6
SP - 678
EP - 686
JO - Brain research. Gene expression patterns
JF - Brain research. Gene expression patterns
SN - 1567-133X
IS - 7
ER -