Abstract
A global survey of RNA from 14 fetal and 12 adult human organs by RT-PCR determined the expression patterns of 790 genes encoding DNA-binding transcription factors. The data can be sorted to identify sets of transcription factors with expression relatively restricted to a given organ or to particular organ groups. These data are a resource to help define the spectrum of transcription factor control, contribute to the elucidation of transcription factor cascades responsible for the development and maintenance of each organ, and provide a baseline to study the effects of disease or developmental defects.
Original language | English (US) |
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Pages (from-to) | 678-686 |
Number of pages | 9 |
Journal | Gene Expression Patterns |
Volume | 6 |
Issue number | 7 |
DOIs | |
State | Published - Oct 1 2006 |
Keywords
- Expression survey
- RT-PCR
- Transcription factor
ASJC Scopus subject areas
- Molecular Biology
- Genetics
- Developmental Biology