A comprehensive survey of DNA-binding transcription factor gene expression in human fetal and adult organs

Y. Megan Kong, Raymond J. MacDonald, Xiaofei Wen, Peng Yang, Victor M. Barbera, Galvin H. Swift

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A global survey of RNA from 14 fetal and 12 adult human organs by RT-PCR determined the expression patterns of 790 genes encoding DNA-binding transcription factors. The data can be sorted to identify sets of transcription factors with expression relatively restricted to a given organ or to particular organ groups. These data are a resource to help define the spectrum of transcription factor control, contribute to the elucidation of transcription factor cascades responsible for the development and maintenance of each organ, and provide a baseline to study the effects of disease or developmental defects.

Original languageEnglish (US)
Pages (from-to)678-686
Number of pages9
JournalGene Expression Patterns
Volume6
Issue number7
DOIs
StatePublished - Oct 2006

Fingerprint

Transcription Factors
Gene Expression
DNA
Maintenance
RNA
Polymerase Chain Reaction
Surveys and Questionnaires
Genes

Keywords

  • Expression survey
  • RT-PCR
  • Transcription factor

ASJC Scopus subject areas

  • Genetics
  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Developmental Neuroscience

Cite this

A comprehensive survey of DNA-binding transcription factor gene expression in human fetal and adult organs. / Kong, Y. Megan; MacDonald, Raymond J.; Wen, Xiaofei; Yang, Peng; Barbera, Victor M.; Swift, Galvin H.

In: Gene Expression Patterns, Vol. 6, No. 7, 10.2006, p. 678-686.

Research output: Contribution to journalArticle

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