A computer program for displaying two-dimensional gel electrophoresis data

Albert Alexander; Bryan Cullen; Kirsten Emigholz; Michael V. Norgard; John J. Monahan

doi:10.1016/0003-2697(80)90253-5

A computer program for displaying two-dimensional gel electrophoresis data

Albert Alexander, Bryan Cullen, Kirsten Emigholz, Michael V. Norgard, John J. Monahan

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

A computer program is described which facilitates comparison between the pattern of spots seen on different two-dimensional polyacrylamide electrophoresis gels. Essentially, the position of each spot is replotted on a graph by the computer using its molecular weight and isoelectric point as coordinates. An intensity factor is also assigned to each point by the operator which will determine the size and shape of the final plotted spot on the computer drawn figure. The resulting plot makes it more feasible to compare patterns of spots between independently run two-dimensional electrophoresis gels.

Original language	English (US)
Pages (from-to)	176-183
Number of pages	8
Journal	Analytical biochemistry
Volume	103
Issue number	1
DOIs	https://doi.org/10.1016/0003-2697(80)90253-5
State	Published - Mar 15 1980

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology
Cell Biology

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AU - Monahan, John J.

PY - 1980/3/15

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AB - A computer program is described which facilitates comparison between the pattern of spots seen on different two-dimensional polyacrylamide electrophoresis gels. Essentially, the position of each spot is replotted on a graph by the computer using its molecular weight and isoelectric point as coordinates. An intensity factor is also assigned to each point by the operator which will determine the size and shape of the final plotted spot on the computer drawn figure. The resulting plot makes it more feasible to compare patterns of spots between independently run two-dimensional electrophoresis gels.

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A computer program for displaying two-dimensional gel electrophoresis data

Abstract

ASJC Scopus subject areas

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