A controlled trial of steroid therapy in massive hepatic necrosis

A. J. Ware, R. E. Jones, J. W. Shorey, B. Combes

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

An abbreviated, prospective, controlled trial of corticosteroid therapy in massive hepatic necrosis associated with acute viral hepatits is reported. A high rate of recovery (7 of 11) was found among those patients receiving placebo therapy. The four patients treated with corticosteroids all died. Although the study group is small, these findings indicate that, with supportive care alone, a substantial number of such patients will recover from this serious illness. Since the condition is relatively rare, definitive evaluation of the efficacy of steroid therapy in improving this survival rate will require evaluation by a number of centers in cooperation.

Original languageEnglish (US)
Pages (from-to)130-133
Number of pages4
JournalAmerican Journal of Gastroenterology
Volume62
Issue number2
StatePublished - 1974

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Massive Hepatic Necrosis
Steroids
Adrenal Cortex Hormones
Therapeutics
Survival Rate
Placebos

ASJC Scopus subject areas

  • Gastroenterology

Cite this

A controlled trial of steroid therapy in massive hepatic necrosis. / Ware, A. J.; Jones, R. E.; Shorey, J. W.; Combes, B.

In: American Journal of Gastroenterology, Vol. 62, No. 2, 1974, p. 130-133.

Research output: Contribution to journalArticle

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