A cross-national relationship between sugar consumption and major depression?

Arthur N. Westover, Lauren B. Marangell

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

We bave preliminarily investigated the hypothesis that sugar consumption may impact the prevalence of major depression by correlating per capita consumption of sugar with the prevalence of major depression. Major depression prevalence data (annual rate/100) was obtained from the Cross-National Epidemiology of Major Depression and Bipolar Disorder study [Weissman et al., 1996]. Sugar consumption data from 1991 was obtained from the Food and Agricultural Organization of the United Nations. For the primary analysis, sugar consumption rates (cal/cap/day) were correlated with the annual rate of major depression, using the Pearson correlation coefficient. For the six countries with available data for the primary analysis, there was a highly significant correlation between sugar consumption and the annual rate of depression (Pearson correlation 0.948, P=0.004). Naturally, a correlation does not necessarily imply etiology. Caveats such as the limited number of countries with available data must be considered. Although speculative, there are some mechanistic reasons to consider that sugar consumption may directly impact the prevalence of major depression. Possible relationships between sugar consumption, β-endorphins, and oxidative stress are discussed.

Original languageEnglish (US)
Pages (from-to)118-120
Number of pages3
JournalDepression and Anxiety
Volume16
Issue number3
DOIs
StatePublished - 2002

Fingerprint

Depression
Endorphins
United Nations
Bipolar Disorder
Epidemiology
Oxidative Stress

Keywords

  • Cytokines
  • Depression
  • Diet
  • Endorphins
  • Oxidative stress
  • Sucrose
  • Sweetening agents
  • Taste

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Psychology(all)
  • Clinical Psychology

Cite this

A cross-national relationship between sugar consumption and major depression? / Westover, Arthur N.; Marangell, Lauren B.

In: Depression and Anxiety, Vol. 16, No. 3, 2002, p. 118-120.

Research output: Contribution to journalArticle

@article{0ef0a0dcd4d94bccb405e60af6ed8d9b,
title = "A cross-national relationship between sugar consumption and major depression?",
abstract = "We bave preliminarily investigated the hypothesis that sugar consumption may impact the prevalence of major depression by correlating per capita consumption of sugar with the prevalence of major depression. Major depression prevalence data (annual rate/100) was obtained from the Cross-National Epidemiology of Major Depression and Bipolar Disorder study [Weissman et al., 1996]. Sugar consumption data from 1991 was obtained from the Food and Agricultural Organization of the United Nations. For the primary analysis, sugar consumption rates (cal/cap/day) were correlated with the annual rate of major depression, using the Pearson correlation coefficient. For the six countries with available data for the primary analysis, there was a highly significant correlation between sugar consumption and the annual rate of depression (Pearson correlation 0.948, P=0.004). Naturally, a correlation does not necessarily imply etiology. Caveats such as the limited number of countries with available data must be considered. Although speculative, there are some mechanistic reasons to consider that sugar consumption may directly impact the prevalence of major depression. Possible relationships between sugar consumption, β-endorphins, and oxidative stress are discussed.",
keywords = "Cytokines, Depression, Diet, Endorphins, Oxidative stress, Sucrose, Sweetening agents, Taste",
author = "Westover, {Arthur N.} and Marangell, {Lauren B.}",
year = "2002",
doi = "10.1002/da.10054",
language = "English (US)",
volume = "16",
pages = "118--120",
journal = "Depression and Anxiety",
issn = "1091-4269",
publisher = "Wiley-Blackwell",
number = "3",

}

TY - JOUR

T1 - A cross-national relationship between sugar consumption and major depression?

AU - Westover, Arthur N.

AU - Marangell, Lauren B.

PY - 2002

Y1 - 2002

N2 - We bave preliminarily investigated the hypothesis that sugar consumption may impact the prevalence of major depression by correlating per capita consumption of sugar with the prevalence of major depression. Major depression prevalence data (annual rate/100) was obtained from the Cross-National Epidemiology of Major Depression and Bipolar Disorder study [Weissman et al., 1996]. Sugar consumption data from 1991 was obtained from the Food and Agricultural Organization of the United Nations. For the primary analysis, sugar consumption rates (cal/cap/day) were correlated with the annual rate of major depression, using the Pearson correlation coefficient. For the six countries with available data for the primary analysis, there was a highly significant correlation between sugar consumption and the annual rate of depression (Pearson correlation 0.948, P=0.004). Naturally, a correlation does not necessarily imply etiology. Caveats such as the limited number of countries with available data must be considered. Although speculative, there are some mechanistic reasons to consider that sugar consumption may directly impact the prevalence of major depression. Possible relationships between sugar consumption, β-endorphins, and oxidative stress are discussed.

AB - We bave preliminarily investigated the hypothesis that sugar consumption may impact the prevalence of major depression by correlating per capita consumption of sugar with the prevalence of major depression. Major depression prevalence data (annual rate/100) was obtained from the Cross-National Epidemiology of Major Depression and Bipolar Disorder study [Weissman et al., 1996]. Sugar consumption data from 1991 was obtained from the Food and Agricultural Organization of the United Nations. For the primary analysis, sugar consumption rates (cal/cap/day) were correlated with the annual rate of major depression, using the Pearson correlation coefficient. For the six countries with available data for the primary analysis, there was a highly significant correlation between sugar consumption and the annual rate of depression (Pearson correlation 0.948, P=0.004). Naturally, a correlation does not necessarily imply etiology. Caveats such as the limited number of countries with available data must be considered. Although speculative, there are some mechanistic reasons to consider that sugar consumption may directly impact the prevalence of major depression. Possible relationships between sugar consumption, β-endorphins, and oxidative stress are discussed.

KW - Cytokines

KW - Depression

KW - Diet

KW - Endorphins

KW - Oxidative stress

KW - Sucrose

KW - Sweetening agents

KW - Taste

UR - http://www.scopus.com/inward/record.url?scp=0036431349&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036431349&partnerID=8YFLogxK

U2 - 10.1002/da.10054

DO - 10.1002/da.10054

M3 - Article

C2 - 12415536

AN - SCOPUS:0036431349

VL - 16

SP - 118

EP - 120

JO - Depression and Anxiety

JF - Depression and Anxiety

SN - 1091-4269

IS - 3

ER -