A cross-sectional survey of urinary iodine status in Latvia

Ilze Konrade, Lolita Neimane, Marina Makrecka, Ieva Strele, Edgars Liepinsh, Aivars Lejnieks, Parsla Vevere, Ugis Gruntmanis, Valdis Pirags, Maija Dambrova

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Background and objective: A nationwide survey of schoolchildren was conducted to detect regional differences in urinary iodine excretion in Latvia and to compare the results with data from the newborn thyroid-stimulating hormone (TSH) screening database as well with the results of a similar study performed in Latvia 10 years ago. Materials and methods: We conducted a cross-sectional school-based cluster survey of 915 children aged 9-12 years in 46 randomly selected schools in all regions of Latvia. Urine samples, questionnaires on the consumption of iodized salt and information on socioeconomic status were collected. TSH levels in newborns were also measured. Results: The median creatinine-standardized urinary iodine concentration (UIC) in our study was 107.3 mg/g Cr. UIC measurements indicative of mild iodine deficiency were present in 31.6%, moderate deficiency in 11.9% and severe deficiency in 2.8% of the participants. The prevalence of iodine deficiency was the highest in the southeastern region of Latgale and the northeastern region of Vidzeme. The prevalence of TSH values >5 mIU/L followed a similar pattern. The self-reported prevalence of regular iodized salt consumption was 10.2%. Children from urban schools had a significantly lower UIC than children from rural schools. Conclusions: Our findings suggest that although the overall median UIC in Latvian schoolchildren falls within the lower normal range, almost 50% of the schoolchildren are iodine.

Original languageEnglish (US)
Pages (from-to)124-129
Number of pages6
JournalMedicina (Lithuania)
Volume50
Issue number2
DOIs
StatePublished - Jan 1 2014

Fingerprint

Latvia
Iodine
Cross-Sectional Studies
Thyrotropin
Newborn Infant
Social Class
Creatinine
Reference Values
Urine
Databases

Keywords

  • Deficiency
  • Iodine
  • Iodized salt
  • Thyroid stimulating hormone

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Konrade, I., Neimane, L., Makrecka, M., Strele, I., Liepinsh, E., Lejnieks, A., ... Dambrova, M. (2014). A cross-sectional survey of urinary iodine status in Latvia. Medicina (Lithuania), 50(2), 124-129. https://doi.org/10.1016/j.medici.2014.06.003

A cross-sectional survey of urinary iodine status in Latvia. / Konrade, Ilze; Neimane, Lolita; Makrecka, Marina; Strele, Ieva; Liepinsh, Edgars; Lejnieks, Aivars; Vevere, Parsla; Gruntmanis, Ugis; Pirags, Valdis; Dambrova, Maija.

In: Medicina (Lithuania), Vol. 50, No. 2, 01.01.2014, p. 124-129.

Research output: Contribution to journalArticle

Konrade, I, Neimane, L, Makrecka, M, Strele, I, Liepinsh, E, Lejnieks, A, Vevere, P, Gruntmanis, U, Pirags, V & Dambrova, M 2014, 'A cross-sectional survey of urinary iodine status in Latvia', Medicina (Lithuania), vol. 50, no. 2, pp. 124-129. https://doi.org/10.1016/j.medici.2014.06.003
Konrade I, Neimane L, Makrecka M, Strele I, Liepinsh E, Lejnieks A et al. A cross-sectional survey of urinary iodine status in Latvia. Medicina (Lithuania). 2014 Jan 1;50(2):124-129. https://doi.org/10.1016/j.medici.2014.06.003
Konrade, Ilze ; Neimane, Lolita ; Makrecka, Marina ; Strele, Ieva ; Liepinsh, Edgars ; Lejnieks, Aivars ; Vevere, Parsla ; Gruntmanis, Ugis ; Pirags, Valdis ; Dambrova, Maija. / A cross-sectional survey of urinary iodine status in Latvia. In: Medicina (Lithuania). 2014 ; Vol. 50, No. 2. pp. 124-129.
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