A cycloaddition strategy for the synthesis of thiirane-containing glycomimetics

Martín Avalos, Reyes Babiano, Pedro Cintas, Fernando R. Clemente, Ruth Gordillo, Michael B. Hursthouse, José L. Jiménez, Mark E. Light, Juan C. Palacios

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


This manuscript describes a one-pot, selective synthesis of optically active thiiranes by [3+2] cycloaddition of mesoionic dipoles with sugar aldehydes. Overall, the result is the formation of monosaccharide mimetics that display numerous functional groups for molecular recognition.

Original languageEnglish (US)
Pages (from-to)2265-2268
Number of pages4
JournalTetrahedron Asymmetry
Issue number16
StatePublished - Sep 13 2001

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry


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