A Descent into the Nuage: The Maelstrom of Transposon Control

Kathryn A O'Donnell-Mendell; Kathleen H. Burns; Jef D. Boeke

doi:10.1016/j.devcel.2008.07.016

A Descent into the Nuage: The Maelstrom of Transposon Control

Kathryn A O'Donnell-Mendell, Kathleen H. Burns, Jef D. Boeke

Research output: Contribution to journal › Short survey › peer-review

14 Scopus citations

Abstract

In this issue of Developmental Cell, Soper et al. (2008) report that the mammalian MAELSTROM (MAEL) protein is critical for transposon silencing in the male germline. Loss of MAEL is associated with meiotic failure and DNA damage, suggesting that efficient transposable element restraining mechanisms must be in place for the preservation of germline integrity.

Original language	English (US)
Pages (from-to)	179-181
Number of pages	3
Journal	Developmental cell
Volume	15
Issue number	2
DOIs	https://doi.org/10.1016/j.devcel.2008.07.016
State	Published - Aug 12 2008

ASJC Scopus subject areas

Molecular Biology
General Biochemistry, Genetics and Molecular Biology
Developmental Biology
Cell Biology

Access to Document

10.1016/j.devcel.2008.07.016

Cite this

@article{87d725ac1bfc42ffadedd09604f68e7c,

title = "A Descent into the Nuage: The Maelstrom of Transposon Control",

abstract = "In this issue of Developmental Cell, Soper et al. (2008) report that the mammalian MAELSTROM (MAEL) protein is critical for transposon silencing in the male germline. Loss of MAEL is associated with meiotic failure and DNA damage, suggesting that efficient transposable element restraining mechanisms must be in place for the preservation of germline integrity.",

author = "O'Donnell-Mendell, {Kathryn A} and Burns, {Kathleen H.} and Boeke, {Jef D.}",

year = "2008",

month = aug,

day = "12",

doi = "10.1016/j.devcel.2008.07.016",

language = "English (US)",

volume = "15",

pages = "179--181",

journal = "Developmental cell",

issn = "1534-5807",

publisher = "Cell Press",

number = "2",

}

TY - JOUR

T1 - A Descent into the Nuage

T2 - The Maelstrom of Transposon Control

AU - O'Donnell-Mendell, Kathryn A

AU - Burns, Kathleen H.

AU - Boeke, Jef D.

PY - 2008/8/12

Y1 - 2008/8/12

N2 - In this issue of Developmental Cell, Soper et al. (2008) report that the mammalian MAELSTROM (MAEL) protein is critical for transposon silencing in the male germline. Loss of MAEL is associated with meiotic failure and DNA damage, suggesting that efficient transposable element restraining mechanisms must be in place for the preservation of germline integrity.

AB - In this issue of Developmental Cell, Soper et al. (2008) report that the mammalian MAELSTROM (MAEL) protein is critical for transposon silencing in the male germline. Loss of MAEL is associated with meiotic failure and DNA damage, suggesting that efficient transposable element restraining mechanisms must be in place for the preservation of germline integrity.

UR - http://www.scopus.com/inward/record.url?scp=48549099827&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=48549099827&partnerID=8YFLogxK

U2 - 10.1016/j.devcel.2008.07.016

DO - 10.1016/j.devcel.2008.07.016

M3 - Short survey

C2 - 18694557

AN - SCOPUS:48549099827

SN - 1534-5807

VL - 15

SP - 179

EP - 181

JO - Developmental cell

JF - Developmental cell

IS - 2

ER -

A Descent into the Nuage: The Maelstrom of Transposon Control

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this