A Descent into the Nuage: The Maelstrom of Transposon Control

Kathryn A O'Donnell-Mendell, Kathleen H. Burns, Jef D. Boeke

Research output: Contribution to journalShort survey

14 Scopus citations

Abstract

In this issue of Developmental Cell, Soper et al. (2008) report that the mammalian MAELSTROM (MAEL) protein is critical for transposon silencing in the male germline. Loss of MAEL is associated with meiotic failure and DNA damage, suggesting that efficient transposable element restraining mechanisms must be in place for the preservation of germline integrity.

Original languageEnglish (US)
Pages (from-to)179-181
Number of pages3
JournalDevelopmental cell
Volume15
Issue number2
DOIs
StatePublished - Aug 12 2008

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

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