A Descent into the Nuage: The Maelstrom of Transposon Control

Kathryn A O'Donnell-Mendell, Kathleen H. Burns, Jef D. Boeke

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

In this issue of Developmental Cell, Soper et al. (2008) report that the mammalian MAELSTROM (MAEL) protein is critical for transposon silencing in the male germline. Loss of MAEL is associated with meiotic failure and DNA damage, suggesting that efficient transposable element restraining mechanisms must be in place for the preservation of germline integrity.

Original languageEnglish (US)
Pages (from-to)179-181
Number of pages3
JournalDevelopmental Cell
Volume15
Issue number2
DOIs
StatePublished - Aug 12 2008

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DNA Transposable Elements
DNA Damage
DNA
Proteins

ASJC Scopus subject areas

  • Developmental Biology

Cite this

A Descent into the Nuage : The Maelstrom of Transposon Control. / O'Donnell-Mendell, Kathryn A; Burns, Kathleen H.; Boeke, Jef D.

In: Developmental Cell, Vol. 15, No. 2, 12.08.2008, p. 179-181.

Research output: Contribution to journalArticle

O'Donnell-Mendell, Kathryn A ; Burns, Kathleen H. ; Boeke, Jef D. / A Descent into the Nuage : The Maelstrom of Transposon Control. In: Developmental Cell. 2008 ; Vol. 15, No. 2. pp. 179-181.
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