A direct radioimmunoassay of cortico-sterone is described requiring as little as 1–2 μl of rat serum. After methanol inactivation of CBG, serum was assayed with a relatively specific antibody raised against corticosterone-21-hemisuccinate. While this antibody has a significant cross-reaction with cortisol, prior purification is not necessary since cortisol is not produced in the rat.
|Original language||English (US)|
|Number of pages||3|
|State||Published - Mar 1975|
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