A foregut carcinoid tumor causing Zollinger-Ellison syndrome

G. B. Werbel, S. P. Nelson, P. G. Robinson, J. Anastasi, R. J. Joehl, Robert V Rege

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A patient had severe peptic ulcer disease complicated by gastric outlet obstruction and choledochoduodenal fistula. Serum gastrin levels were elevated preoperatively to 340 ng/L. A 1.5-cm histologically benign carcinoid tumor of the antrum of the stomach was found at surgery, and surgical resection of the tumor resulted in normalization of serum gastrin levels and amelioration of the peptic acid diathesis. The patient remains asymptomatic at one year. Immunohistochemical staining demonstrated that the carcinoid indeed contained gastrin along with chromogranin, cholecystokinin, and neuron-specific enolase. This is a case of Zollinger-Ellison syndrome caused by a benign foregut carcinoid (gastric carcinoid-gastrinoma).

Original languageEnglish (US)
Pages (from-to)381-384
Number of pages4
JournalArchives of Surgery
Volume124
Issue number3
StatePublished - 1989

Fingerprint

Zollinger-Ellison Syndrome
Carcinoid Tumor
Gastrins
Stomach
Gastric Outlet Obstruction
Gastrinoma
Chromogranins
Phosphopyruvate Hydratase
Cholecystokinin
Disease Susceptibility
Serum
Peptic Ulcer
Fistula
Digestion
Staining and Labeling
Acids
Neoplasms

ASJC Scopus subject areas

  • Surgery

Cite this

Werbel, G. B., Nelson, S. P., Robinson, P. G., Anastasi, J., Joehl, R. J., & Rege, R. V. (1989). A foregut carcinoid tumor causing Zollinger-Ellison syndrome. Archives of Surgery, 124(3), 381-384.

A foregut carcinoid tumor causing Zollinger-Ellison syndrome. / Werbel, G. B.; Nelson, S. P.; Robinson, P. G.; Anastasi, J.; Joehl, R. J.; Rege, Robert V.

In: Archives of Surgery, Vol. 124, No. 3, 1989, p. 381-384.

Research output: Contribution to journalArticle

Werbel, GB, Nelson, SP, Robinson, PG, Anastasi, J, Joehl, RJ & Rege, RV 1989, 'A foregut carcinoid tumor causing Zollinger-Ellison syndrome', Archives of Surgery, vol. 124, no. 3, pp. 381-384.
Werbel GB, Nelson SP, Robinson PG, Anastasi J, Joehl RJ, Rege RV. A foregut carcinoid tumor causing Zollinger-Ellison syndrome. Archives of Surgery. 1989;124(3):381-384.
Werbel, G. B. ; Nelson, S. P. ; Robinson, P. G. ; Anastasi, J. ; Joehl, R. J. ; Rege, Robert V. / A foregut carcinoid tumor causing Zollinger-Ellison syndrome. In: Archives of Surgery. 1989 ; Vol. 124, No. 3. pp. 381-384.
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