Abstract
CrCl2-induced olefination of aldehydes using methyl dichloroacetate exclusively generates (E)-α,β-unsaturated esters in excellent yields. The intermediate α-chloro-β-hydroxy adducts could also be isolated in good yields under conditions of limited reagent.
Original language | English (US) |
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Pages (from-to) | 5917-5920 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 45 |
Issue number | 30 |
DOIs | |
State | Published - Jul 19 2004 |
Keywords
- Chromium
- Condensations
- Halo esters
- Olefination
- Stereoselective
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry