A history of the DNA repair and mutagenesis field. The discovery of base excision repair.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

This article reviews the early history of the discovery of an DNA repair path way designated as base excision repair(BER),since in contrast to the enzyme-catalyzed removal of damaged bases from DNA as nucleotides [called nucleotide excision repair(NER)],BER involves the removal of damage dor in appropriate bases,such as the presence of uracil instead of thymine ,from DNA as free bases.

Original languageEnglish (US)
Pages (from-to)A35-A39
JournalDNA Repair
Volume37
DOIs
StatePublished - Jan 1 2016

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Mutagenesis
DNA Repair
Repair
DNA
Nucleotides
Thymine
Uracil
History
Enzymes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

Cite this

A history of the DNA repair and mutagenesis field. The discovery of base excision repair. / Friedberg, Errol C.

In: DNA Repair, Vol. 37, 01.01.2016, p. A35-A39.

Research output: Contribution to journalArticle

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