A “KU” new sensor for cytosolic DNA in T cells

Jianjun Wu, Nan Yan

Research output: Contribution to journalArticlepeer-review

Abstract

Adaptive immune cells are usually not equipped with pattern recognition receptors. In this issue of Immunity, Wang et al. revealed an “innate-like” cytosolic DNA-sensing mechanism by the KU complex in aged CD4+ T cells, which exacerbates aging-related autoimmunity.

Original languageEnglish (US)
Pages (from-to)603-605
Number of pages3
JournalImmunity
Volume54
Issue number4
DOIs
StatePublished - Apr 13 2021
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

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