A mad partner for Shugoshin in meiosis

Research output: Contribution to journalArticle


The centromeric cohesin protector Shugoshin (Sgo) and the spindle checkpoint protein Mad2 are known to act in distinct pathways for ensuring accurate chromosome segregation during eukaryotic cell division. In this issue of The EMBO Journal, Orth et al (2011) describe an unexpected physical interaction between vertebrate Sgo and Mad2, as well as indications of their potential mutual regulation in meiosis.

Original languageEnglish (US)
Pages (from-to)2759-2761
Number of pages3
JournalEMBO Journal
Issue number14
Publication statusPublished - Jul 20 2011


ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Neuroscience(all)

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