A magnetic resonance image study of age-related changes in human putamen nuclei

W. M. McDonald, M. Husain, P. M. Doraiswamy, G. Figiel, O. Boyko, K. R R Krishnan

Research output: Contribution to journalArticle

39 Scopus citations

Abstract

Putamen nuclei were assessed in 36 normal volunteers using magnetic resonance imaging and a systematic sampling method. There was a significant decrease in the volume of the putamen nuclei with advancing age (r = —0.74, p < 0.0001), and an associated decline in the volume of the caudate nuclei (r = 0.60, p < 0.0001). The implications of these findings in age-associated motor abnormalities are discussed.

Original languageEnglish (US)
Pages (from-to)57-60
Number of pages4
JournalNeuroReport
Volume2
Issue number1
DOIs
StatePublished - Jan 1991

Keywords

  • Age-related changes
  • Magnetic resonance image
  • Putamen nuclei
  • Stereology

ASJC Scopus subject areas

  • Neuroscience(all)

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  • Cite this

    McDonald, W. M., Husain, M., Doraiswamy, P. M., Figiel, G., Boyko, O., & Krishnan, K. R. R. (1991). A magnetic resonance image study of age-related changes in human putamen nuclei. NeuroReport, 2(1), 57-60. https://doi.org/10.1097/00001756-199101000-00014