A monoclonal antibody that blocks VEGF binding to VEGFR2 (KDR/Flk-1) inhibits vascular expression of Flk-1 and tumor growth in an orthotopic human breast cancer model

Medicine & Life Sciences

• Vascular Endothelial Growth Factor A 100%
• Monoclonal Antibodies 84%
• Breast Neoplasms 74%
• Blood Vessels 68%
• Growth 58%
• Neoplasms 37%
• Adipose Tissue 12%
• Breast 11%
• Microvessels 7%
• Tumor Burden 6%
• Nude Mice 6%
• Therapeutic Uses 5%
• Epithelium 5%
• Immunoglobulin G 5%
• Down-Regulation 5%
• Neoplasm Metastasis 4%
• Control Groups 3%
• Lung 3%
• Therapeutics 1%

Chemical Compounds

• Block Like Crystal 78%
• Fat 57%
• Analeptic Agent 36%
• Growth Factor 34%
• Neutralization 29%