Abstract
To fulfil its lipid phosphatase function, PTEN must be in close proximity to the plasma membrane where its substrates reside. PTEN translocation to the plasma membrane is an active process that is mediated by the myosin-based transport machinery. MyosinV controls PTEN membrane association and thus, PTEN-mediated cell growth in neurons.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1177-1179 |
| Number of pages | 3 |
| Journal | Nature cell biology |
| Volume | 11 |
| Issue number | 10 |
| DOIs | |
| State | Published - 2009 |
ASJC Scopus subject areas
- Cell Biology