A motor driving PTEN

Jing Zhou, Luis F. Parada

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

To fulfil its lipid phosphatase function, PTEN must be in close proximity to the plasma membrane where its substrates reside. PTEN translocation to the plasma membrane is an active process that is mediated by the myosin-based transport machinery. MyosinV controls PTEN membrane association and thus, PTEN-mediated cell growth in neurons.

Original languageEnglish (US)
Pages (from-to)1177-1179
Number of pages3
JournalNature cell biology
Volume11
Issue number10
DOIs
StatePublished - Oct 9 2009

ASJC Scopus subject areas

  • Cell Biology

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    Zhou, J., & Parada, L. F. (2009). A motor driving PTEN. Nature cell biology, 11(10), 1177-1179. https://doi.org/10.1038/ncb1009-1177