A motor driving PTEN

Jing Zhou, Luis F. Parada

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

To fulfil its lipid phosphatase function, PTEN must be in close proximity to the plasma membrane where its substrates reside. PTEN translocation to the plasma membrane is an active process that is mediated by the myosin-based transport machinery. MyosinV controls PTEN membrane association and thus, PTEN-mediated cell growth in neurons.

Original languageEnglish (US)
Pages (from-to)1177-1179
Number of pages3
JournalNature Cell Biology
Volume11
Issue number10
DOIs
StatePublished - 2009

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Cell Membrane
PTEN Phosphohydrolase
Myosins
Lipids
Neurons
Membranes
Growth

ASJC Scopus subject areas

  • Cell Biology

Cite this

Zhou, J., & Parada, L. F. (2009). A motor driving PTEN. Nature Cell Biology, 11(10), 1177-1179. https://doi.org/10.1038/ncb1009-1177

A motor driving PTEN. / Zhou, Jing; Parada, Luis F.

In: Nature Cell Biology, Vol. 11, No. 10, 2009, p. 1177-1179.

Research output: Contribution to journalArticle

Zhou, J & Parada, LF 2009, 'A motor driving PTEN', Nature Cell Biology, vol. 11, no. 10, pp. 1177-1179. https://doi.org/10.1038/ncb1009-1177
Zhou, Jing ; Parada, Luis F. / A motor driving PTEN. In: Nature Cell Biology. 2009 ; Vol. 11, No. 10. pp. 1177-1179.
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