A naphthalimide fluorescent sensor for Zn2+ based on photo-induced electron transfer

Jiangli Fan, Yunkou Wu, Xiaojun Peng

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


A new Zn2+ fluorescent sensor NIDPA (1) which takes 1,8-naphthalimide as a reporting group and di-2-picolylamine (DPA) as a recognizing group has been synthesized via simple steps. Based on photo-induced electron transfer (PET) mechanism, NIDPA has a nearly 5-fold fluorescent enhancement under simulated physiological conditions corresponding to the binding of Zn2+. Apparent dissociation constant for Zn2+ (Kd) is in the sub-nM range, and Ca2+, Mg2+, Fe3+, Ni2+, and Cr3+ have little influence on fluorescence enhancement.

Original languageEnglish (US)
Article numberCL-040809
Pages (from-to)1392-1393
Number of pages2
JournalChemistry Letters
Issue number10
StatePublished - Oct 5 2004

ASJC Scopus subject areas

  • Chemistry(all)


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