Lesions such as ischemia, which result in myocardial cell death, are accompanied by cellular influx of calcium ions which localize within the mitochondria in the crystalline structure hydroxyapatite. Using 99Tc(m) stannous pyrophosphate, an agent which labels hydroxyapatite for bone scanning, the authors have produced scintillation camera images of experimental myocardial infarcts in dogs. Tracer localization disappears with time, suggesting application of this method to fresh infarcts.
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging