A novel family of biodegradable poly(ester amide) elastomers

Hao Cheng, Paulina S. Hill, Daniel J. Siegwart, Nathaniel Vacanti, Abigail K R Lytton-Jean, Seung Woo Cho, Anne Ye, Robert Langer, Daniel G. Anderson

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

Biodegradable elastomeric materials have particular utility in tissue engineering applications because their compliance under force closely resembles the elastic nature of many human tissues. A family of biodegradable poly(ester amide) elastomers were developed, with excellent elasticity under hydrated conditions, good in vivo biocompatibility and a slow degradation rate. This study sheds light on the structure-property relationship behind designing biodegradable elastomeric materials.

Original languageEnglish (US)
Pages (from-to)H95-H100
JournalAdvanced Materials
Volume23
Issue number12
DOIs
StatePublished - Mar 25 2011

Keywords

  • nerve regeneration
  • regenerative medicine
  • scaffolds
  • tissue engineering
  • young's modulus

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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