A novel family of biodegradable poly(ester amide) elastomers

Hao Cheng, Paulina S. Hill, Daniel J. Siegwart, Nathaniel Vacanti, Abigail K R Lytton-Jean, Seung Woo Cho, Anne Ye, Robert Langer, Daniel G. Anderson

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

Biodegradable elastomeric materials have particular utility in tissue engineering applications because their compliance under force closely resembles the elastic nature of many human tissues. A family of biodegradable poly(ester amide) elastomers were developed, with excellent elasticity under hydrated conditions, good in vivo biocompatibility and a slow degradation rate. This study sheds light on the structure-property relationship behind designing biodegradable elastomeric materials.

Original languageEnglish (US)
Pages (from-to)H95-H100
JournalAdvanced Materials
Volume23
Issue number12
DOIs
StatePublished - Mar 25 2011

Keywords

  • nerve regeneration
  • regenerative medicine
  • scaffolds
  • tissue engineering
  • young's modulus

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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  • Cite this

    Cheng, H., Hill, P. S., Siegwart, D. J., Vacanti, N., Lytton-Jean, A. K. R., Cho, S. W., Ye, A., Langer, R., & Anderson, D. G. (2011). A novel family of biodegradable poly(ester amide) elastomers. Advanced Materials, 23(12), H95-H100. https://doi.org/10.1002/adma.201003482