A novel family of biodegradable poly(ester amide) elastomers

Hao Cheng, Paulina S. Hill, Daniel J. Siegwart, Nathaniel Vacanti, Abigail K R Lytton-Jean, Seung Woo Cho, Anne Ye, Robert Langer, Daniel G. Anderson

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Biodegradable elastomeric materials have particular utility in tissue engineering applications because their compliance under force closely resembles the elastic nature of many human tissues. A family of biodegradable poly(ester amide) elastomers were developed, with excellent elasticity under hydrated conditions, good in vivo biocompatibility and a slow degradation rate. This study sheds light on the structure-property relationship behind designing biodegradable elastomeric materials.

Original languageEnglish (US)
JournalAdvanced Materials
Volume23
Issue number12
DOIs
StatePublished - Mar 25 2011

Fingerprint

Elastomers
Amides
Esters
Biocompatibility
Tissue engineering
Elasticity
Tissue
Degradation
elastomeric
Compliance

Keywords

  • nerve regeneration
  • regenerative medicine
  • scaffolds
  • tissue engineering
  • young's modulus

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Cheng, H., Hill, P. S., Siegwart, D. J., Vacanti, N., Lytton-Jean, A. K. R., Cho, S. W., ... Anderson, D. G. (2011). A novel family of biodegradable poly(ester amide) elastomers. Advanced Materials, 23(12). https://doi.org/10.1002/adma.201003482

A novel family of biodegradable poly(ester amide) elastomers. / Cheng, Hao; Hill, Paulina S.; Siegwart, Daniel J.; Vacanti, Nathaniel; Lytton-Jean, Abigail K R; Cho, Seung Woo; Ye, Anne; Langer, Robert; Anderson, Daniel G.

In: Advanced Materials, Vol. 23, No. 12, 25.03.2011.

Research output: Contribution to journalArticle

Cheng, H, Hill, PS, Siegwart, DJ, Vacanti, N, Lytton-Jean, AKR, Cho, SW, Ye, A, Langer, R & Anderson, DG 2011, 'A novel family of biodegradable poly(ester amide) elastomers', Advanced Materials, vol. 23, no. 12. https://doi.org/10.1002/adma.201003482
Cheng, Hao ; Hill, Paulina S. ; Siegwart, Daniel J. ; Vacanti, Nathaniel ; Lytton-Jean, Abigail K R ; Cho, Seung Woo ; Ye, Anne ; Langer, Robert ; Anderson, Daniel G. / A novel family of biodegradable poly(ester amide) elastomers. In: Advanced Materials. 2011 ; Vol. 23, No. 12.
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