A novel inhibitor of pyruvate dehydrogenase kinase stimulates myocardial carbohydrate oxidation in diet-induced obesity

Cheng Yang Wu, Santhosh Satapati, Wenjun Gui, R. Max Wynn, Gaurav Sharma, Mingliang Lou, Xiangbing Qi, Shawn C. Burgess, Craig Malloy, Chalermchai Khemtong, A. Dean Sherry, David T. Chuang, Matthew E. Merritt

Research output: Contribution to journalArticle

3 Citations (Scopus)
Original languageEnglish (US)
Pages (from-to)9604-9613
Number of pages10
JournalJournal of Biological Chemistry
Volume293
Issue number25
DOIs
StatePublished - Jan 1 2018

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Pyruvate Dehydrogenase Complex
Obese Mice
Protein-Serine-Threonine Kinases
Protein Kinase Inhibitors
Pyruvic Acid
Inbred C57BL Mouse
Energy Metabolism
Oxidation-Reduction
Obesity
Carbohydrates
Diet
pyruvate dehydrogenase (acetyl-transferring) kinase

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

Cite this

A novel inhibitor of pyruvate dehydrogenase kinase stimulates myocardial carbohydrate oxidation in diet-induced obesity. / Wu, Cheng Yang; Satapati, Santhosh; Gui, Wenjun; Max Wynn, R.; Sharma, Gaurav; Lou, Mingliang; Qi, Xiangbing; Burgess, Shawn C.; Malloy, Craig; Khemtong, Chalermchai; Dean Sherry, A.; Chuang, David T.; Merritt, Matthew E.

In: Journal of Biological Chemistry, Vol. 293, No. 25, 01.01.2018, p. 9604-9613.

Research output: Contribution to journalArticle

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AU - Satapati, Santhosh

AU - Gui, Wenjun

AU - Max Wynn, R.

AU - Sharma, Gaurav

AU - Lou, Mingliang

AU - Qi, Xiangbing

AU - Burgess, Shawn C.

AU - Malloy, Craig

AU - Khemtong, Chalermchai

AU - Dean Sherry, A.

AU - Chuang, David T.

AU - Merritt, Matthew E.

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