A pilot tolerability and efficacy study of Levetiracetam in patients with chronic myoclonus

Steven J. Frucht, Elan D. Louis, Cathy Chuang, Stanley Fahn

Research output: Contribution to journalArticle

100 Scopus citations

Abstract

Levetiracetam was recently approved as adjunctive therapy for partial onset seizures. The authors conducted an open-label trial of levetiracetam in eight patients with chronic myoclonus. Patients were assessed by using the Unified Myoclonus Rating Scale. Levetiracetam was well tolerated. Three of five patients with cortical myoclonus experienced reductions in their myoclonus scores, providing support for a larger, placebo-controlled trial in cortical myoclonus.

Original languageEnglish (US)
Pages (from-to)1112-1114
Number of pages3
JournalNeurology
Volume57
Issue number6
DOIs
StatePublished - Sep 25 2001
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology

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