A pilot tolerability and efficacy study of Levetiracetam in patients with chronic myoclonus

Steven J. Frucht; Elan D. Louis; Cathy Chuang; Stanley Fahn

doi:10.1212/WNL.57.6.1112

A pilot tolerability and efficacy study of Levetiracetam in patients with chronic myoclonus

Steven J. Frucht, Elan D. Louis, Cathy Chuang, Stanley Fahn

Research output: Contribution to journal › Article › peer-review

114 Scopus citations

Abstract

Levetiracetam was recently approved as adjunctive therapy for partial onset seizures. The authors conducted an open-label trial of levetiracetam in eight patients with chronic myoclonus. Patients were assessed by using the Unified Myoclonus Rating Scale. Levetiracetam was well tolerated. Three of five patients with cortical myoclonus experienced reductions in their myoclonus scores, providing support for a larger, placebo-controlled trial in cortical myoclonus.

Original language	English (US)
Pages (from-to)	1112-1114
Number of pages	3
Journal	Neurology
Volume	57
Issue number	6
DOIs	https://doi.org/10.1212/WNL.57.6.1112
State	Published - Sep 25 2001
Externally published	Yes

ASJC Scopus subject areas

Clinical Neurology

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abstract = "Levetiracetam was recently approved as adjunctive therapy for partial onset seizures. The authors conducted an open-label trial of levetiracetam in eight patients with chronic myoclonus. Patients were assessed by using the Unified Myoclonus Rating Scale. Levetiracetam was well tolerated. Three of five patients with cortical myoclonus experienced reductions in their myoclonus scores, providing support for a larger, placebo-controlled trial in cortical myoclonus.",

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AU - Chuang, Cathy

AU - Fahn, Stanley

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AB - Levetiracetam was recently approved as adjunctive therapy for partial onset seizures. The authors conducted an open-label trial of levetiracetam in eight patients with chronic myoclonus. Patients were assessed by using the Unified Myoclonus Rating Scale. Levetiracetam was well tolerated. Three of five patients with cortical myoclonus experienced reductions in their myoclonus scores, providing support for a larger, placebo-controlled trial in cortical myoclonus.

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A pilot tolerability and efficacy study of Levetiracetam in patients with chronic myoclonus

Abstract

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