A planar QRS-T angle >90° is associated with multivessel coronary artery disease in patients undergoing coronary angiography

Background: The aim of the study was to investigate the severity of coronary artery disease (CAD) in patients who had a planar QRS-T angle >90° versus ≤90° . Material/Methods: Coronary angiography was performed in 1,229 consecutive patients. Obstructive CAD was diagnosed if there was >50% obstruction of ≥1 major coronary artery. All QRS-T angle measurements were made from a 12-lead electrocardiogram by 2 authors who agreed on the measurement and who were blinded to the coronary angiographic findings. A QRS-T angle >90° was considered abnormal. Results: Obstructive CAD of 2 or 3 vessels was present in 309 of 495 patients (62%) with a planar QRS-T angle >90° and in 250 of 734 patients (34%) with a planar QRS-T angle ≤90° . (p<0.0001). Stepwise logistic regression analyses showed that significant independent risk factors for 2- or 3-vessel CAD were age (odds ratio =1.05), male gender (odds ratio =1.8), black race (odds ratio =0.34), unstable angina (odds ratio =0.16), positive stress test (odds ratio =3.0), hypertension (odds ratio =3.0), dyslipidemia (odds ratio =2.9), QRS-T angle (odds ratio =7.2), left bundle branch block (odds ratio =2.9), right bundle branch block (odds ratio =0.17), smoking (odds ratio =9.7), and body mass index ≥30 kg/m² (odds ratio =1.5). Conclusions: The prevalence of 2- or 3-vessel obstructive CAD was significantly higher in patients with a planar QRS-T angle >90° than in patients with a planar QRS-T angle ≤90° (pp&lt0.0001).