A preliminary report of the use of botulinum toxin type A in infants with clubfoot

Four case studies

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

This report describes the use of botulinum toxin type A (BTX-A) in four infants with very severe clubfoot deformity. The gastrocnemius and posterior tibial muscles were injected with BTX-A after the patients reached a treatment plateau in physical therapy. Significant improvement in foot dorsiflexion and foot flexibility was seen in two patients, and surgery was not required. Surgical intervention was necessary in the remaining two patients, both of whom were ultimately diagnosed with a demyelinating neuropathy. The use of botulinum toxin as an adjunct to conservative care in infants with clubfoot is discussed.

Original languageEnglish (US)
Pages (from-to)533-538
Number of pages6
JournalJournal of Pediatric Orthopaedics
Volume20
Issue number4
DOIs
StatePublished - 2000

Fingerprint

Clubfoot
Type A Botulinum Toxins
Foot
Infant Care
Botulinum Toxins
Muscles
Therapeutics

Keywords

  • Botulinum toxin type A
  • Clubfoot
  • Pediatric

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery
  • Orthopedics and Sports Medicine

Cite this

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title = "A preliminary report of the use of botulinum toxin type A in infants with clubfoot: Four case studies",
abstract = "This report describes the use of botulinum toxin type A (BTX-A) in four infants with very severe clubfoot deformity. The gastrocnemius and posterior tibial muscles were injected with BTX-A after the patients reached a treatment plateau in physical therapy. Significant improvement in foot dorsiflexion and foot flexibility was seen in two patients, and surgery was not required. Surgical intervention was necessary in the remaining two patients, both of whom were ultimately diagnosed with a demyelinating neuropathy. The use of botulinum toxin as an adjunct to conservative care in infants with clubfoot is discussed.",
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T1 - A preliminary report of the use of botulinum toxin type A in infants with clubfoot

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AU - Delgado, Mauricio R.

AU - Wilson, Holly

AU - Johnston, Charles

AU - Richards, Steve

AU - Karol, Lori

PY - 2000

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N2 - This report describes the use of botulinum toxin type A (BTX-A) in four infants with very severe clubfoot deformity. The gastrocnemius and posterior tibial muscles were injected with BTX-A after the patients reached a treatment plateau in physical therapy. Significant improvement in foot dorsiflexion and foot flexibility was seen in two patients, and surgery was not required. Surgical intervention was necessary in the remaining two patients, both of whom were ultimately diagnosed with a demyelinating neuropathy. The use of botulinum toxin as an adjunct to conservative care in infants with clubfoot is discussed.

AB - This report describes the use of botulinum toxin type A (BTX-A) in four infants with very severe clubfoot deformity. The gastrocnemius and posterior tibial muscles were injected with BTX-A after the patients reached a treatment plateau in physical therapy. Significant improvement in foot dorsiflexion and foot flexibility was seen in two patients, and surgery was not required. Surgical intervention was necessary in the remaining two patients, both of whom were ultimately diagnosed with a demyelinating neuropathy. The use of botulinum toxin as an adjunct to conservative care in infants with clubfoot is discussed.

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KW - Pediatric

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