A prolonged nursery epidemic associated with a newly recognized type of group A streptococcus

John D. Nelson, Hugh C. Dillon, Jorge B. Howard

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

During a six-month period 69 infants in a newborn nursery were colonized with group A streptococci. Fifty-one had omphalitis, two infected circumcision wounds, and one each had meningitis, primary peritonitis, and conjunctivitis. Thirteen infants were asymptomatically colonized. Control of the epidemic was difficult. Benzathine penicillin prophylaxis to all infants suppressed active infection but did not eradicate asymptomatic colonization of the umbilical cord. Triple dye treatment of the umbilical cord plus benzathine penicillin prophylaxis eradicated the infection from the nursery. The epidemic streptococcus was a newly recognized "skin strain", provisional type strain 5656-S, not previously known to cause epidemic disease or serious systemic infections.

Original languageEnglish (US)
Pages (from-to)792-796
Number of pages5
JournalThe Journal of Pediatrics
Volume89
Issue number5
DOIs
StatePublished - 1976

Fingerprint

Nurseries
Streptococcus
Penicillin G Benzathine
Umbilical Cord
Infection
Conjunctivitis
Peritonitis
Meningitis
Newborn Infant
Skin
Wounds and Injuries
Therapeutics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

A prolonged nursery epidemic associated with a newly recognized type of group A streptococcus. / Nelson, John D.; Dillon, Hugh C.; Howard, Jorge B.

In: The Journal of Pediatrics, Vol. 89, No. 5, 1976, p. 792-796.

Research output: Contribution to journalArticle

@article{aa36bd98cb3d4892a4a358d2856f1246,
title = "A prolonged nursery epidemic associated with a newly recognized type of group A streptococcus",
abstract = "During a six-month period 69 infants in a newborn nursery were colonized with group A streptococci. Fifty-one had omphalitis, two infected circumcision wounds, and one each had meningitis, primary peritonitis, and conjunctivitis. Thirteen infants were asymptomatically colonized. Control of the epidemic was difficult. Benzathine penicillin prophylaxis to all infants suppressed active infection but did not eradicate asymptomatic colonization of the umbilical cord. Triple dye treatment of the umbilical cord plus benzathine penicillin prophylaxis eradicated the infection from the nursery. The epidemic streptococcus was a newly recognized {"}skin strain{"}, provisional type strain 5656-S, not previously known to cause epidemic disease or serious systemic infections.",
author = "Nelson, {John D.} and Dillon, {Hugh C.} and Howard, {Jorge B.}",
year = "1976",
doi = "10.1016/S0022-3476(76)80809-8",
language = "English (US)",
volume = "89",
pages = "792--796",
journal = "Journal of Pediatrics",
issn = "0022-3476",
publisher = "Mosby Inc.",
number = "5",

}

TY - JOUR

T1 - A prolonged nursery epidemic associated with a newly recognized type of group A streptococcus

AU - Nelson, John D.

AU - Dillon, Hugh C.

AU - Howard, Jorge B.

PY - 1976

Y1 - 1976

N2 - During a six-month period 69 infants in a newborn nursery were colonized with group A streptococci. Fifty-one had omphalitis, two infected circumcision wounds, and one each had meningitis, primary peritonitis, and conjunctivitis. Thirteen infants were asymptomatically colonized. Control of the epidemic was difficult. Benzathine penicillin prophylaxis to all infants suppressed active infection but did not eradicate asymptomatic colonization of the umbilical cord. Triple dye treatment of the umbilical cord plus benzathine penicillin prophylaxis eradicated the infection from the nursery. The epidemic streptococcus was a newly recognized "skin strain", provisional type strain 5656-S, not previously known to cause epidemic disease or serious systemic infections.

AB - During a six-month period 69 infants in a newborn nursery were colonized with group A streptococci. Fifty-one had omphalitis, two infected circumcision wounds, and one each had meningitis, primary peritonitis, and conjunctivitis. Thirteen infants were asymptomatically colonized. Control of the epidemic was difficult. Benzathine penicillin prophylaxis to all infants suppressed active infection but did not eradicate asymptomatic colonization of the umbilical cord. Triple dye treatment of the umbilical cord plus benzathine penicillin prophylaxis eradicated the infection from the nursery. The epidemic streptococcus was a newly recognized "skin strain", provisional type strain 5656-S, not previously known to cause epidemic disease or serious systemic infections.

UR - http://www.scopus.com/inward/record.url?scp=0017109497&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017109497&partnerID=8YFLogxK

U2 - 10.1016/S0022-3476(76)80809-8

DO - 10.1016/S0022-3476(76)80809-8

M3 - Article

VL - 89

SP - 792

EP - 796

JO - Journal of Pediatrics

JF - Journal of Pediatrics

SN - 0022-3476

IS - 5

ER -