A promoter deletion reduces the rate of mitotic, but not meiotic, recombination at the HIS4 locus in yeast

Michael A. White, Peter Detloff, Micheline Strand, Thomas D. Petes

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Abstract

Several investigators have reported that transcription stimulates some types of mitotic recombination in the yeast Saccharomyces cerevisiae. We find that mutations that reduce the rate of trancription of the yeast HIS4 gene in vegetative cells reduce the frequency of mitotic, but not meiotic, recombination events.

Original languageEnglish (US)
Pages (from-to)109-116
Number of pages8
JournalCurrent Genetics
Volume21
Issue number2
DOIs
StatePublished - Feb 1992

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Keywords

  • Gene conversion
  • Recombination
  • Transcription
  • Yeast

ASJC Scopus subject areas

  • Genetics

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