A prospective study of motor recovery following multiple subpial transections

Lauren R. Moo, Scott D. Slotnick, Gregory Krauss, John Hart

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

A prospective study of motor recovery was undertaken in a patient scheduled to undergo multiple subpial transections (MST) of right sensorimotor cortex. Pre-transection, functional MRI (fMRI) and cortical stimulation mapping confirmed left hand motor control within right primary motor cortex. Immediately post-transection, behavioral testing demonstrated preserved strength bilaterally but decreased dexterity in the left hand. Seven weeks post-transection, dexterity returned to normal and left hand finger tapping corresponded with multiple bilateral foci of fMRI activation. At 16 weeks, fMRI activation returned to pre-transection levels. These data indicate that cortical injury due to MST resulted in the temporary recruitment of distant cortical sites which presumably subserved normal motor function during recovery.

Original languageEnglish (US)
Pages (from-to)665-669
Number of pages5
JournalNeuroReport
Volume13
Issue number5
StatePublished - Apr 16 2002

Fingerprint

Hand
Magnetic Resonance Imaging
Prospective Studies
Recovery of Function
Motor Cortex
Fingers
Wounds and Injuries
Sensorimotor Cortex

Keywords

  • Cortex
  • Cortical stimulation
  • Epilepsy
  • fMRI
  • Human
  • Motor
  • Plasticity
  • Recovery
  • Reorganization
  • Surgery

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Moo, L. R., Slotnick, S. D., Krauss, G., & Hart, J. (2002). A prospective study of motor recovery following multiple subpial transections. NeuroReport, 13(5), 665-669.

A prospective study of motor recovery following multiple subpial transections. / Moo, Lauren R.; Slotnick, Scott D.; Krauss, Gregory; Hart, John.

In: NeuroReport, Vol. 13, No. 5, 16.04.2002, p. 665-669.

Research output: Contribution to journalArticle

Moo, LR, Slotnick, SD, Krauss, G & Hart, J 2002, 'A prospective study of motor recovery following multiple subpial transections', NeuroReport, vol. 13, no. 5, pp. 665-669.
Moo, Lauren R. ; Slotnick, Scott D. ; Krauss, Gregory ; Hart, John. / A prospective study of motor recovery following multiple subpial transections. In: NeuroReport. 2002 ; Vol. 13, No. 5. pp. 665-669.
@article{6b2c0aad4fed4334a3badb1a6d452a81,
title = "A prospective study of motor recovery following multiple subpial transections",
abstract = "A prospective study of motor recovery was undertaken in a patient scheduled to undergo multiple subpial transections (MST) of right sensorimotor cortex. Pre-transection, functional MRI (fMRI) and cortical stimulation mapping confirmed left hand motor control within right primary motor cortex. Immediately post-transection, behavioral testing demonstrated preserved strength bilaterally but decreased dexterity in the left hand. Seven weeks post-transection, dexterity returned to normal and left hand finger tapping corresponded with multiple bilateral foci of fMRI activation. At 16 weeks, fMRI activation returned to pre-transection levels. These data indicate that cortical injury due to MST resulted in the temporary recruitment of distant cortical sites which presumably subserved normal motor function during recovery.",
keywords = "Cortex, Cortical stimulation, Epilepsy, fMRI, Human, Motor, Plasticity, Recovery, Reorganization, Surgery",
author = "Moo, {Lauren R.} and Slotnick, {Scott D.} and Gregory Krauss and John Hart",
year = "2002",
month = "4",
day = "16",
language = "English (US)",
volume = "13",
pages = "665--669",
journal = "NeuroReport",
issn = "0959-4965",
publisher = "Lippincott Williams and Wilkins",
number = "5",

}

TY - JOUR

T1 - A prospective study of motor recovery following multiple subpial transections

AU - Moo, Lauren R.

AU - Slotnick, Scott D.

AU - Krauss, Gregory

AU - Hart, John

PY - 2002/4/16

Y1 - 2002/4/16

N2 - A prospective study of motor recovery was undertaken in a patient scheduled to undergo multiple subpial transections (MST) of right sensorimotor cortex. Pre-transection, functional MRI (fMRI) and cortical stimulation mapping confirmed left hand motor control within right primary motor cortex. Immediately post-transection, behavioral testing demonstrated preserved strength bilaterally but decreased dexterity in the left hand. Seven weeks post-transection, dexterity returned to normal and left hand finger tapping corresponded with multiple bilateral foci of fMRI activation. At 16 weeks, fMRI activation returned to pre-transection levels. These data indicate that cortical injury due to MST resulted in the temporary recruitment of distant cortical sites which presumably subserved normal motor function during recovery.

AB - A prospective study of motor recovery was undertaken in a patient scheduled to undergo multiple subpial transections (MST) of right sensorimotor cortex. Pre-transection, functional MRI (fMRI) and cortical stimulation mapping confirmed left hand motor control within right primary motor cortex. Immediately post-transection, behavioral testing demonstrated preserved strength bilaterally but decreased dexterity in the left hand. Seven weeks post-transection, dexterity returned to normal and left hand finger tapping corresponded with multiple bilateral foci of fMRI activation. At 16 weeks, fMRI activation returned to pre-transection levels. These data indicate that cortical injury due to MST resulted in the temporary recruitment of distant cortical sites which presumably subserved normal motor function during recovery.

KW - Cortex

KW - Cortical stimulation

KW - Epilepsy

KW - fMRI

KW - Human

KW - Motor

KW - Plasticity

KW - Recovery

KW - Reorganization

KW - Surgery

UR - http://www.scopus.com/inward/record.url?scp=0037117692&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037117692&partnerID=8YFLogxK

M3 - Article

VL - 13

SP - 665

EP - 669

JO - NeuroReport

JF - NeuroReport

SN - 0959-4965

IS - 5

ER -