A randomized trial of etoposide and G-CSF with or without rituximab for PBSC mobilization in B-cell non-Hodgkin's lymphoma

E. Copelan, B. Pohlman, L. Rybicki, M. Kalaycio, R. Sobecks, S. Andresen, R. Dean, A. Koo, J. Chan, J. Sweetenham, B. Bolwell

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Some reports have suggested that rituximab administration before PBSC mobilization may adversely affect PBSC yield. We conducted a prospective randomized trial of PBSC mobilization using etoposide and G-CSF with or without rituximab to determine whether its addition would adversely affect CD34+ cell yield in patients with non-Hodgkin's lymphoma. Twenty seven patients were mobilized with etoposide and G-CSF and 28 with etoposide, G-CSF and rituximab. There were no adverse consequences of rituximab on CD34+ cell yield, or hematopoietic recovery or immunoglobulin levels after transplantation.

Original languageEnglish (US)
Pages (from-to)101-105
Number of pages5
JournalBone Marrow Transplantation
Volume43
Issue number2
DOIs
StatePublished - Jan 1 2009
Externally publishedYes

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B-Cell Lymphoma
Granulocyte Colony-Stimulating Factor
Etoposide
Non-Hodgkin's Lymphoma
Immunoglobulins
Transplantation
Rituximab

ASJC Scopus subject areas

  • Hematology
  • Transplantation

Cite this

Copelan, E., Pohlman, B., Rybicki, L., Kalaycio, M., Sobecks, R., Andresen, S., ... Bolwell, B. (2009). A randomized trial of etoposide and G-CSF with or without rituximab for PBSC mobilization in B-cell non-Hodgkin's lymphoma. Bone Marrow Transplantation, 43(2), 101-105. https://doi.org/10.1038/bmt.2008.306

A randomized trial of etoposide and G-CSF with or without rituximab for PBSC mobilization in B-cell non-Hodgkin's lymphoma. / Copelan, E.; Pohlman, B.; Rybicki, L.; Kalaycio, M.; Sobecks, R.; Andresen, S.; Dean, R.; Koo, A.; Chan, J.; Sweetenham, J.; Bolwell, B.

In: Bone Marrow Transplantation, Vol. 43, No. 2, 01.01.2009, p. 101-105.

Research output: Contribution to journalArticle

Copelan, E, Pohlman, B, Rybicki, L, Kalaycio, M, Sobecks, R, Andresen, S, Dean, R, Koo, A, Chan, J, Sweetenham, J & Bolwell, B 2009, 'A randomized trial of etoposide and G-CSF with or without rituximab for PBSC mobilization in B-cell non-Hodgkin's lymphoma', Bone Marrow Transplantation, vol. 43, no. 2, pp. 101-105. https://doi.org/10.1038/bmt.2008.306
Copelan, E. ; Pohlman, B. ; Rybicki, L. ; Kalaycio, M. ; Sobecks, R. ; Andresen, S. ; Dean, R. ; Koo, A. ; Chan, J. ; Sweetenham, J. ; Bolwell, B. / A randomized trial of etoposide and G-CSF with or without rituximab for PBSC mobilization in B-cell non-Hodgkin's lymphoma. In: Bone Marrow Transplantation. 2009 ; Vol. 43, No. 2. pp. 101-105.
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