A second generation MRI contrast agent for imaging zinc ions in vivo

Luis M. De León-Rodríguez, Angelo J M Lubag, Jorge A. López, Gabriel Andreu-De-Riquer, José C. Alvarado-Monzón, A. Dean Sherry

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

A Zn 2+ specific GdDOTA derivative containing two bis-(3-pyrazolyl) units was prepared and characterized. Unlike a previously reported Zn 2+ binding agent, the new agent binds to human albumin both in the presence and absence of Zn 2+.

Original languageEnglish (US)
Pages (from-to)480-483
Number of pages4
JournalMedChemComm
Volume3
Issue number4
DOIs
StatePublished - Apr 2012

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Magnetic resonance imaging
Contrast Media
Zinc
Albumins
Ions
Imaging techniques
Derivatives

ASJC Scopus subject areas

  • Biochemistry
  • Pharmaceutical Science

Cite this

De León-Rodríguez, L. M., Lubag, A. J. M., López, J. A., Andreu-De-Riquer, G., Alvarado-Monzón, J. C., & Sherry, A. D. (2012). A second generation MRI contrast agent for imaging zinc ions in vivo. MedChemComm, 3(4), 480-483. https://doi.org/10.1039/c2md00301e

A second generation MRI contrast agent for imaging zinc ions in vivo. / De León-Rodríguez, Luis M.; Lubag, Angelo J M; López, Jorge A.; Andreu-De-Riquer, Gabriel; Alvarado-Monzón, José C.; Sherry, A. Dean.

In: MedChemComm, Vol. 3, No. 4, 04.2012, p. 480-483.

Research output: Contribution to journalArticle

De León-Rodríguez, LM, Lubag, AJM, López, JA, Andreu-De-Riquer, G, Alvarado-Monzón, JC & Sherry, AD 2012, 'A second generation MRI contrast agent for imaging zinc ions in vivo', MedChemComm, vol. 3, no. 4, pp. 480-483. https://doi.org/10.1039/c2md00301e
De León-Rodríguez LM, Lubag AJM, López JA, Andreu-De-Riquer G, Alvarado-Monzón JC, Sherry AD. A second generation MRI contrast agent for imaging zinc ions in vivo. MedChemComm. 2012 Apr;3(4):480-483. https://doi.org/10.1039/c2md00301e
De León-Rodríguez, Luis M. ; Lubag, Angelo J M ; López, Jorge A. ; Andreu-De-Riquer, Gabriel ; Alvarado-Monzón, José C. ; Sherry, A. Dean. / A second generation MRI contrast agent for imaging zinc ions in vivo. In: MedChemComm. 2012 ; Vol. 3, No. 4. pp. 480-483.
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