A severe presentation of acute generalized exanthematous pustulosis with non-infectious circulatory shock in an adolescent

Madeleine O’Brian, Elysha Kolitz, Haneol S. Jeong, Lauren Cao, Travis Vandergriff, Donald A. Glass, Arturo R. Dominguez

Research output: Contribution to journalArticlepeer-review

Abstract

We present a severe case of acute generalized exanthematous pustulosis (AGEP) secondary to trimethoprim-sulfamethoxazole complicated by non-infectious circulatory shock in a 16-year-old boy. Hemodynamic instability has been reported as a complication of AGEP in adults, but is rarely observed in pediatric patients. The patient we present demonstrated characteristic cutaneous findings of AGEP including isolated non-follicular, sterile pustules on a background of erythema with involvement at intertriginous areas and subsequently developed non-infectious circulatory shock. This case expands the spectrum of possible clinical presentations for AGEP in pediatric patients.

Original languageEnglish (US)
Pages (from-to)1267-1271
Number of pages5
JournalPediatric dermatology
Volume38
Issue number5
DOIs
StatePublished - Sep 1 2021

Keywords

  • acute generalized exanthematous pustulosis
  • AGEP
  • hypotension
  • shock
  • trimethoprim-sulfamethoxazole

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dermatology

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