A short biomimetic approach to the fully functionalized bicyclic framework of type A acylphloroglucinols

Elias A. Couladouros, Marianna Dakanali, Konstantinos D. Demadis, Veroniki P. Vidali

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

A biomimetic approach toward type A polyprenylated acylphlorogluclnols (PPAPs) Is described. The method Is based on a C-alkylation-cation cyclization reaction sequence, leading to a convenient buildup of molecular complexity, employing the simple and readily available deoxycohumulone and an appropriately functionalized hydroxy halide. Thus, a versatile construction of the fully functlonallzed bicyclic framework of type A PPAPs (5) was achieved.

Original languageEnglish (US)
Pages (from-to)4430-4433
Number of pages4
JournalOrganic Letters
Volume11
Issue number19
DOIs
StatePublished - Oct 1 2009

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Biomimetics
Cyclization
biomimetics
alkylation
Alkylation
halides
Cations
cations
deoxycohumulone

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

A short biomimetic approach to the fully functionalized bicyclic framework of type A acylphloroglucinols. / Couladouros, Elias A.; Dakanali, Marianna; Demadis, Konstantinos D.; Vidali, Veroniki P.

In: Organic Letters, Vol. 11, No. 19, 01.10.2009, p. 4430-4433.

Research output: Contribution to journalArticle

Couladouros, Elias A. ; Dakanali, Marianna ; Demadis, Konstantinos D. ; Vidali, Veroniki P. / A short biomimetic approach to the fully functionalized bicyclic framework of type A acylphloroglucinols. In: Organic Letters. 2009 ; Vol. 11, No. 19. pp. 4430-4433.
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