A young man in "double-trouble": Hallucinations and cranial nerve palsies

TY - JOUR

T1 - A young man in "double-trouble"

T2 - Hallucinations and cranial nerve palsies

AU - Bradshaw, Michael J.

AU - Lisak, Robert P.

AU - Meltzer, Ethan

AU - Melamed, Esther

AU - Lucas, Ashlea

AU - Freeman, Leorah

AU - Frohman, Teresa C.

AU - Costello, Kathleen

AU - Balcer, Laura

AU - Galetta, Steven

AU - Chitnis, Tanuja

AU - Zamvil, Scott S.

AU - Frohman, Elliot M.

N1 - Funding Information: The Article Processing Charge was funded by National Multiple Sclerosis Society. Funding Information: The National Multiple Sclerosis Society Case Conference Proceedings are both a live educational Webinar, in conjunction with a peer review publishing initiative from the monthly “Diagnostic and Treatment Challenges in MS and Neuroimmunology Webinars”; sponsored by the National Multiple Sclerosis Society Fellowship Training Program; and Directed by Elliot M. Frohman, MD, PhD, and Teresa C. Frohman, MPAS, MSCS, PA-C, from the Dell Medical School at the University of Texas at Austin. The authors wish to express their gratitude to their medical illustrator, Mr. Jason Ooi, for his evidence-based rendition of the putative mechanisms underlying the development of anti-NMDAR mediated encephalitis. Funding Information: Diagnostic and Treatment Challenges in MS and Neuro-immunology Webinars is sponsored by the National Multiple Sclerosis Fellowship Training Program. Funding Information: M.J. Bradshaw served as an editorial board member of Continuum. R.P. Lisak served on the scientific advisory boards of Syntimmune, Alexion, Argenix, National Multiple Sclerosis Society, Myasthenia Gravis Foundation of America, and Guillain-Barre Syndrome/CIDP Foundation; received travel funding and/or speaker honoraria from Teva; is section editor of Neuroimmunology and Clinical Neuropharmacology; is on the editorial board of Immunology Research; receives publishing royalties from Blackwell and Oxford; consulted for GLG Consulting, Insight Consulting, AlphaSights Consulting, Slingshot Consulting, and Informa Pharma Consulting; served on the speaker’s bureau of Teva; previously served as immediate past president and member of Consortium of Multiple Sclerosis Centers; is on the Executive Committee of the Board of Directors; was a member of the Board of Governors of the Foundation of the Consortium of Multiple Sclerosis Centers Society; is on the Board of Governors for National Multiple Sclerosis Society Michigan Chapter; and received research support from Teva, Alexion, Genentech, Novartis, Medimmune, Chigai, and Ra Pharmaceuticals paid to Wayne State University. E. Meltzer reports no disclosures. E. Melamed served on the scientific advisory board of EMD and received research support from the William & Ella Owens Medical Research Foundation. A. Lucas reports no disclosures. L. Freeman holds a patent for method of attenuation and repair of brain lesions in patients with multiple sclerosis by improvement of impaired cerebral tissue perfusion and received research support from Biogen. T.C. Frohman received travel funding and/or speaker honoraria from Novartis, Acorda, Genzyme, and Biogen; is on the editorial board of NMSS Publication; receives publishing royalties for UpToDate; consulted for Acorda, Novartis, and Genzyme; and received research support from the NIH and NMSS. K. Costello received travel funding from Advanced Studies in Medicine and Johns Hopkins Medicine. L. Balcer received research support from Biogen, NIH/NINHS, and NMSS; her spouse is co-owner of a patent for NMDA receptor antibody assay. S. Galetta is on the editorial boards of Neurology and Journal of Neuro-ophthalmology. T. Chitnis served on the clinical advisory boards of Novartis, Celgene, and Sanofi-Genzyme; consulted for Biogen, Celgene, Novartis, and Sanofi-Genzyme; and received research support from Merck-Serono, Verily, NIH, MNSS, Peabody Foundation, Consortium for MS Centers, and Guthy-Jackson. S.S. Zamvil served on data safety monitoring boards of Opexa, BioMS, Teva, and Eli Lilly; is a member of the clinical advisory board of the Myelin Repair Foundation; is deputy editor of Neurology® Neuroimmunology & Neuroinflammation; holds a patent for aquaporin-4 peptides; consulted for Biogen, Teva, EMD Serono, Genzyme, Novartis, and Roche; serves on the speakers’ bureau of Advanced Health Media and Biogen; and received research support from Biogen, Teva, NIH, NMSS, and Alexander M. and June L. Maisin Foundation. E.M. Frohman received speaker honoraria from Genzyme, Novartis, and Acorda; served on the editorial boards of Journal of Neurology and Journal of Neurology, Neurosurgery, and Psychiatry; receives publishing royalties from UpTo-Date and Cambridge University Press; served on the speakers’ bureau of Genzyme, Novartis, and Acorda; and received research support from the National MS Society. Full disclosure form information provided by the authors is available with the full text of this article at Neurology. org/NN.

PY - 2019/1/1

Y1 - 2019/1/1

UR - http://www.scopus.com/inward/record.url?scp=85060824356&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85060824356&partnerID=8YFLogxK

U2 - 10.1212/NXI.0000000000000526

DO - 10.1212/NXI.0000000000000526

M3 - Article

C2 - 30637300

AN - SCOPUS:85060824356

VL - 6

JO - Neurology: Neuroimmunology and NeuroInflammation

JF - Neurology: Neuroimmunology and NeuroInflammation

SN - 2332-7812

IS - 1

M1 - e526

ER -