AAV-dominant negative tumor necrosis factor (DN-TNF) gene transfer to the striatum does not rescue medium spiny neurons in the YAC128 mouse model of Huntington's disease

Agriculture & Biology

• tumor necrosis factors 100%
• gene transfer 79%
• animal models 65%
• neurons 61%
• Parkinson disease 30%
• Alzheimer disease 27%
• mice 17%
• genetically modified organisms 16%
• inflammation 13%
• neurodegenerative diseases 9%
• young adults 8%
• brain 5%
• proteins 5%
• drugs 4%
• testing 2%

Medicine & Life Sciences

• Huntington Disease 82%
• Tumor Necrosis Factor-alpha 52%
• Neurons 45%
• Genes 29%
• Transgenic Mice 19%
• Parkinson Disease 18%
• Alzheimer Disease 17%
• Corpus Striatum 14%
• Pathology 14%
• Dominant Genes 10%
• Nerve Degeneration 9%
• Neuroprotection 7%
• Neurodegenerative Diseases 6%
• Young Adult 6%
• Complementary DNA 6%
• Proteins 5%
• Animal Models 5%
• Inflammation 4%
• Brain 3%
• Pharmaceutical Preparations 3%

Chemical Compounds

• Complementary DNA 38%
• Protein 30%
• Drug 19%
• Reduction 16%
• Time 13%