TY - JOUR
T1 - Accuracy of 64-multidetector computed tomography in diagnosis of adnexal tumors
AU - Gatreh-Samani, Fatemeh
AU - Tarzamni, Mohammad
AU - Olad-Sahebmadarek, Elaheh
AU - Dastranj, Ali
AU - Afrough, Aimaz
N1 - Funding Information:
This research was supported by Tabriz University of Medical Sciences.
PY - 2011
Y1 - 2011
N2 - Background: Adnexal cancers are in fifth place among the tumors with the highest mortality in the female population. The aim of the present study was to evaluate the accuracy of Multi-detector computed tomography (MDCT) on a 64-multislice CT scanner in the detection and differentiation of adnexal masses stages. Methods. During the present prospective study, 95 women with a primary diagnosis of ovarian mass in base of clinical examination and ultrasonographic findings underwent preoperative evaluation by a 64-slice MDCT with a section thickness of 0.6 mm, 50% overlap and reconstructed images. Afterward, results of MDCT were compared with surgical and histopathological findings, and the sensitivity, specificity, positive and negative predictive value and accuracy were determined. Results: The mean age of patients was 48.63 13.93 years. MDCT diagnosed 25 (26.3%) masses to be benign and 70 (73.7%) to be malignant (sensitivity, specificity, positive and negative predictive value and accuracy were 92.8%, 88.0%, 95.5%, 81.4% and 91.5% respectively). The sensitivity and specificity of MDCT in determining local extension was 72.2% and 93.4% respectively. And the sensitivity and specificity of MDCT in determining peritoneal seeding and liver extension was 81.8% and 93% respectively. Estimated stage was significantly agreed with the surgical (Cohen's Kappa () = 0.891) and histopathological findings ( = 0.858). Conclusion: MDCT is a highly sensitive and specific diagnostic method in evaluation of adnexal masses and successfully stage the tumor in consistent with surgery and histopathology.
AB - Background: Adnexal cancers are in fifth place among the tumors with the highest mortality in the female population. The aim of the present study was to evaluate the accuracy of Multi-detector computed tomography (MDCT) on a 64-multislice CT scanner in the detection and differentiation of adnexal masses stages. Methods. During the present prospective study, 95 women with a primary diagnosis of ovarian mass in base of clinical examination and ultrasonographic findings underwent preoperative evaluation by a 64-slice MDCT with a section thickness of 0.6 mm, 50% overlap and reconstructed images. Afterward, results of MDCT were compared with surgical and histopathological findings, and the sensitivity, specificity, positive and negative predictive value and accuracy were determined. Results: The mean age of patients was 48.63 13.93 years. MDCT diagnosed 25 (26.3%) masses to be benign and 70 (73.7%) to be malignant (sensitivity, specificity, positive and negative predictive value and accuracy were 92.8%, 88.0%, 95.5%, 81.4% and 91.5% respectively). The sensitivity and specificity of MDCT in determining local extension was 72.2% and 93.4% respectively. And the sensitivity and specificity of MDCT in determining peritoneal seeding and liver extension was 81.8% and 93% respectively. Estimated stage was significantly agreed with the surgical (Cohen's Kappa () = 0.891) and histopathological findings ( = 0.858). Conclusion: MDCT is a highly sensitive and specific diagnostic method in evaluation of adnexal masses and successfully stage the tumor in consistent with surgery and histopathology.
KW - Adnexal diseases
KW - diagnostic imaging
KW - ovarian neoplasms
KW - spiral computed
KW - tomography
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U2 - 10.1186/1757-2215-4-15
DO - 10.1186/1757-2215-4-15
M3 - Article
C2 - 21846406
AN - SCOPUS:80051658990
SN - 1757-2215
VL - 4
JO - Journal of Ovarian Research
JF - Journal of Ovarian Research
IS - 1
M1 - 15
ER -