Achromobacter xylosoxidans: An unusual neonatal pathogen

Y. R. Hearn, R. M. Gander

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Perinatal acquisition of a rare pediatric pathogen, Achromobacter xylosoxidans, with evidence for in utero transmission, is described. Cultures from the mother and neonate demonstrated A. xylosoxidans. An ascending bacterial infection in the mother with clinical chorioamnionitis is presented as the probable mode of transmission. Postmortem examination of the infant confirmed Achromobacter meningitis. In contrast to the current case with transmission from mother to neonate, previously published neonatal cases of Achromobacter infections indicate that nosocomial transmission of the organism is most common (79%). In addition, the literature review revealed a high mortality associated with meningitis (77%), frequent hydrocephalus, and subsequent neurologic sequelae (36%). To the authors' knowledge, this is the first documented case of maternal-fetal transfer of A. xylosoxidans.

Original languageEnglish (US)
Pages (from-to)211-214
Number of pages4
JournalAmerican Journal of Clinical Pathology
Volume96
Issue number2
StatePublished - 1991

Fingerprint

Achromobacter denitrificans
Achromobacter
Mothers
Meningitis
Newborn Infant
Chorioamnionitis
Hydrocephalus
Cross Infection
Bacterial Infections
Nervous System
Autopsy
Pediatrics
Mortality

Keywords

  • Achromobacter xylosoxidans
  • Neonatal meningitis

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Achromobacter xylosoxidans : An unusual neonatal pathogen. / Hearn, Y. R.; Gander, R. M.

In: American Journal of Clinical Pathology, Vol. 96, No. 2, 1991, p. 211-214.

Research output: Contribution to journalArticle

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