Acrokeratoelastoidosis

Euphemia W. Mu, Adnan Mir, Shane A. Meehan, Nathalie Nguyen

Research output: Contribution to journalArticle

Abstract

Acrokeratoelastoidosis is a rare palmoplantar keratoderma. We report the case of a 32-year old man with multiple keratotic papules and plaques on the peripheral margins of his hands and feet. Histopathologic evaluation showed compact orthokeratosis; Verhoeff van Gieson stain showed thin and fragmented elastic fibers. The differential diagnosis includes focal acral hyperkeratosis, which has a similar presentation but with normal elastic fibers. Treatment of acrokeratoelastoidosis is often disappointing, with minimal response to topical glucocorticoids, keratolytics, retinoids, cryotherapy, and lasers.

Original languageEnglish (US)
JournalDermatology Online Journal
Volume21
Issue number12
StatePublished - Dec 1 2015

ASJC Scopus subject areas

  • Dermatology

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    Mu, E. W., Mir, A., Meehan, S. A., & Nguyen, N. (2015). Acrokeratoelastoidosis. Dermatology Online Journal, 21(12).